San Francisco Giants vs Baltimore Orioles Prediction 8/30/25 MLB Picks Today

The Baltimore Orioles and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Baltimore Orioles vs. San Francisco Giants prediction.

Starting Pitching Matchup

The Baltimore Orioles will send out Trevor Rogers for the start here and Rogers is 7-2 with a 1.40 ERA and 76 strikeouts this season. In his career, Rogers is 0-1 with a 2.63 ERA and 12 strikeouts against the Giants. Carson Seymour will get the start for San Francisco here and is 0-1 with a 3.74 ERA and 16 strikeouts this season. This will be Seymour’s first career start against the Orioles.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to rebound from a 15-8 loss at the hands of the Giants on Friday to sit at 60-75 this season. After this series, the Orioles will head on the road for a series against the San Diego Padres.

Orioles Lose 5 Straight & 8 Of Last 9

Adley Rutschman has 70 hits with 16 doubles, 9 homers and 29 RBIs. Jackson Holliday has 120 hits with 18 doubles, 2 triples, 15 homers and 49 RBIs. Gunnar Henderson has 132 hits with 30 doubles, 5 triples, 16 home runs and 59 RBIs with 20 stolen bases and 119 strikeouts while Holliday has a team-high 120 strikeouts as well this season. 

Why the Baltimore Orioles will win

• The Orioles have won each of their last five day games following a road loss.
• The Giants have lost six of their last seven home games against the Orioles following a win.
• The Giants have failed to cover the run line in 19 of their last 21 home games against AL East opponents following a win.
• The Orioles have covered the run line in each of their last five day games following a road loss.

Baltimore Orioles Player Prop Facts

• Trevor Rogers has recorded six or more strikeouts in each of his last five appearances.
• Gunnar Henderson has recorded at least one hit in each of the Orioles’ last 10 games as favorites.
• Trevor Rogers has recorded a win in four of his last five road appearances.
• Tyler O’Neill has hit at least one home run in five of his last six appearances with his team as a favorite against NL West opponents.
• Dylan Carlson has recorded a Double in four of his last five appearances.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to add on to their win over the Orioles from Friday’s opener to sit at 67-68 this season. After this set, the Giants will head on the road for a series at Coors Field against the Colorado Rockies.

Giants Win 6th Straight

Jung Hoo Lee has 125 hits including a team-high 30 doubles along with 10 triples, 7 home runs and 48 RBIs with 10 stolen bases while Heliot Ramos has 135 hits with 23 doubles, 16 home runs and 57 RBIs. Wilmer Flores also 14 home runs and 64 RBIs while Tyler Fitzgerald has 9 stolen bases as well on the year. Matt Chapman also has 84 hits with 18 home runs and 48 RBIs along with 16 doubles and Willy Adames has 110 hits with 18 doubles, 24 home runs and 69 RBIs of his own this season. 

Why the San Francisco Giants will win

• The Giants have won each of their last four games as underdogs.
• The Orioles have lost four of their last five games as favorites.
• The Orioles have failed to cover the run line in each of their last seven games as favorites.
• The Giants have covered the run line in each of their last five games as underdogs.

San Francisco Giants Player Prop Facts

• Matt Chapman has hit at least one home run in each of his last three appearances with the Giants as home underdogs.
• Dominic Smith has recorded at least one hit in each of his last 11 appearances against opponents that held a losing record.
• Rafael Devers ranks 9th amongst qualified players for On Base Percentage (.380) this season.

Total Runs Facts

• Nine of the Giants’ last 10 day games against AL East opponents have gone OVER the total runs line.
• Five of the Orioles’ last six day games after playing the previous day have gone UNDER the total runs line.

Baltimore Orioles vs. San Francisco Giants Prediction

I’m leaning towards the Orioles here. I think this is a spot for Trevor Rogers to act as the stopper for his club as I’m still not 100% committed to this Giants lineup against lefties, especially with how well Rogers has been pitching. Give me Baltimore in this one to get some revenge.