San Francisco Giants vs LA Dodgers Prediction 9/26/26 MLB Picks Today

The Los Angeles Dodgers and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. San Francisco Giants prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Blake Snell for the start here and Snell is 4-1 with a 1.86 ERA and 52 strikeouts this season. Matt Wilkinson will start for the Giants and is 1-3 with a 3.65 ERA and 18 strikeouts this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to add on to their 2-0 win over San Francisco last time out to sit at 98-62 this season.

Dodgers Snap Two-Game Slide

Freddie Freeman leads the Dodgers with a team-high 167 hits while adding 32 doubles, a triple, 16 home runs, and 70 RBIs so far this season. Shohei Ohtani paces Los Angeles in power with a team-high 30 home runs and 81 RBIs alongside 142 hits, 26 doubles, and 4 triples on the year. Andy Pages has tied Ohtani for the team lead in RBIs with 81 while logging 139 hits, 26 doubles, 2 triples, and 22 home runs. Kyle Tucker has contributed 124 hits with 23 doubles, 4 triples, 17 home runs, and 70 RBIs, while Max Muncy has added 121 hits with 26 doubles, a triple, 29 home runs, and 76 RBIs. Teoscar Hernández has chipped in 117 hits with 17 doubles, 2 triples, 16 home runs, and 64 RBIs for Los Angeles up to this point in the season.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to bounce back from their loss to the Dodgers last time out to sit at 65-95 this season.

Giants Lose 3 In A Row

Jung Hoo Lee leads the Giants with a team-high 149 hits while adding 31 doubles, 4 triples, 10 home runs, and 57 RBIs so far this season. Rafael Devers paces San Francisco across the board in power, leading the team with 37 home runs and 98 RBIs alongside 144 hits, 36 doubles, and a triple on the year. Willy Adames has contributed 107 hits with 25 doubles, a triple, 21 home runs, and 51 RBIs. Matt Chapman has logged 72 hits with 18 doubles, a triple, 7 home runs, and 42 RBIs for San Francisco up to this point in the season.

Los Angeles Dodgers @ San Francisco Giants Betting Trends: September 26, 2026

• Probable Starting Pitcher: Matt Wilkinson      Record this season: 1-3      ERA: 3.65
• Home Record: 1-1
• Last 5 against Dodgers: 0-0

Why the San Francisco Giants will win

• The Dodgers have lost three of their last four games as road favorites following a road win.
• The home team has won five of the last six games between the Dodgers and Giants.
• The Dodgers have failed to cover the run line in each of their last four day games following a road win.
• The Giants have covered the run line in six of their last eight games as home underdogs after playing the previous day.
• The Dodgers have trailed after 5 innings in three of their last four day games against NL West opponents.
• The Giants have won the first inning in six of their last eight home games against NL opponents.

• Probable Starting Pitcher: Blake Snell      Record this season: 4-1      ERA: 1.86
• Road Record: 2-0
• Last 5 against Giants: 3-1

Why the Los Angeles Dodgers will win

• The Giants have lost each of their last 10 day games against NL West opponents that held a winning record.
• The Dodgers have won each of their last seven games against NL West opponents that held a losing record.
• The Dodgers have covered the run line in each of their last six games against the Giants.
• The Giants have failed to cover the run line each of their last five games against teams that held a winning record.
• The Dodgers have led after 5 innings in each of their last five road games against NL West opponents that held a losing record.
• The Dodgers have led after 3 innings in four of their last five road games.

Total Runs Facts

• Each of the Dodgers’ last six day games against NL West opponents have gone UNDER the total runs line.
• Each of the Giants’ last five games have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of Blake Snell’s last seven road appearances as a starter.
• There has been at least one run scored in the first inning in seven of the Giants’ last eight games against NL West opponents.

San Francisco Giants Player Prop Facts

• Bo Davidson has recorded a hit in each of the Giants’ last four games.
• Drew Gilbert has hit a home run in three of the Giants’ last 10 home games against NL West opponents.

Los Angeles Dodgers Player Prop Facts

• Blake Snell has recorded a win in five of his last six appearances against NL opponents that held a losing record.
• Blake Snell has recorded eight or more strikeouts in each of his last seven Saturday appearances against teams that held a losing record.
• Andy Pages has recorded at least one hit in each of his last eight road appearances.
• Will Smith has hit a home run in three of the Dodgers’ last five games against the Giants.

Matchup/League Facts

• The Giants rank 30th in the league for walks this season (446).
• The Giants rank 29th in the league for on-base percentage this season (.307).
• The Dodgers rank 1st in the league for opponent batting average this season (.218).
• The Dodgers rank 1st in the league for hits allowed this season (1145).

Los Angeles Dodgers vs. San Francisco Giants Prediction

I’m on the Dodgers in this one. I’m just hoping the Dodgers don’t give Snell another quick hook in this start but I still think that Los Angeles can get the job done here. L.A. has been the best team in baseball in September against left-handed pitching and I look for the Dodgers to get to Wilkinson for another win ahead of the playoffs. Give me the Dodgers.