San Francisco Giants vs San Diego Padres Prediction 4-5-24 Picks

The San Diego Padres and the San Francisco Giants meet Friday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. San Francisco Giants prediction.

San Diego Padres Team Preview

The San Diego Padres come into this game looking to build on a 3-2 win over St. Louis last time out, salvaging a win from their three-game series. Luis Campusano leads the Padres with 12 hits and a .400 batting average along with 7 RBIs while Jake Cronenworth and Manny Machado each have 7 RBIs as well with Machado adding 2 homers and 2 doubles. Fernando Tatis Jr. has a team-high 3 home runs while Cronenworth has 3 doubles and a triple as well this season. Machado has the dubious distinction of leading the Padres with 7 strikeouts so far this season. Dylan Cease will start for the Padres here and is 0-1 with a 3.86 ERA and 6 strikeouts this season. The Padres will meet the Cubs, Dodgers, and Brewers after this series.

San Diego Padres Team Facts

• The Padres have won each of their last five games as underdogs against the Giants.
• The Padres have covered the run line in each of their last six games as underdogs against the Giants.
• The Padres have led after 7 innings in three of their last four games as underdogs against NL West opponents.
• The Padres have led after 3 innings in three of their last four games as underdogs against National League opponents.
• The Padres have led after 5 innings in three of their last four games as underdogs against National League opponents.

San Francisco Giants Team Preview

The San Francisco Giants come into this one looking to bounce back after being swept by the Dodgers, losing 5-4 in Wednesday’s series finale. Michael Conforto leads the Giants with 10 hits, including 3 home runs, 2 doubles and a team-high 9 RBIs along with a .370 batting average, but shares the team lead with LaMonte Wade Jr. with 9 strikeouts so far this season. Matt Chapman and Jorge Soler each have a pair of home runs as well with Chapman adding 2 doubles and 6 RBIs as well on the year. Jordan Hicks will start for the Giants here and is 1-0 with a 0.00 ERA and 6 strikeouts this season.

San Francisco Giants Team Facts

• The Giants have lost each of their last five games as favorites against the Padres following a loss.
• The Giants have failed to cover the run line in each of their last 11 games as favorites against NL West opponents following a road loss.
• The Giants have trailed after 7 innings in each of their last six Friday home games.
• The Giants have trailed after 3 innings in each of their last three Friday games as home favorites.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last six Friday day games.

Padres vs. Giants Prediction

I’m on the Giants here. I think the Padres still get too much respect from oddsmakers, and the fact that this game is even near a coin flip is a representation of that. In my eyes, the Giants are the better team and Hicks looked a lot better in his debut than Cease did. Sure, Cease is the name brand, but he really regressed in 2023 and I need to see that he’s found his 2022 form before backing him in a spot like this. With this being the Giants’ home opener, I have to roll with San Francisco here.