San Francisco Giants vs St. Louis Cardinals Prediction 9-27-24 MLB Picks

The St. Louis Cardinals and the San Francisco Giants meet Friday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs St. Louis Cardinals Prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Miles Mikolas for the start here and Mikolas is 9-11 with a 5.35 ERA and 43 strikeouts this season. In his last five starts against the Giants, Mikolas is 4-1 with a 3.10 ERA and 26 strikeouts. Landen Roupp will get the nod for the Giants here and is 1-1 with a 2.70 ERA and 43 strikeouts this season. This will be Roupp’s first career start against the Cardinals.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this one looking to finish the season strong after winning their series with the Colorado Rockies despite a 10-8 loss in Thursday’s series finale. The series win kept the win streak alive for the Cardinals who also have series wins against the Guardians and Pirates in the last week and a half.

Cardinals Trying To Clinch Winning Record

Nolan Arenado has 154 hits along with 22 doubles and 70 RBIs while Brendan Donovan has 157 hits and 69 RBIs with 33 doubles. Nolan Gorman has 19 home runs along with 50 RBIs in addition to 15 doubles while Masyn Winn has a .265 batting average, 153 hits, 30 doubles, and 11 stolen bases. Paul Goldschmidt also has 171 K’s and a team-high 22 homers with 62 RBIs and 11 stolen bases while Gorman has 151 strikeouts as well this season. Alec Burleson also has 21 home runs and 74 RBIs as well this year.

Why the St. Louis Cardinals will win

• The Cardinals have won five of their last six games as road underdogs against National League opponents following a road loss.
• The Giants have lost five of their last six games as favorites against the Cardinals following a loss.
• The Cardinals have covered the run line in nine of their last 10 night games against NL West opponents following a loss.
• The Giants have failed to cover the run line in seven of their last eight games against the Cardinals following a loss.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to close the season on a high as well after their series win against the Arizona Diamondbacks despite an 8-2 loss to Arizona in Wednesday’s series finale. The series win added to San Fran’s series win streak that includes the Royals and Orioles over the last week and a half as well.

Giants Looking For Winning Record Of Their Own

Thairo Estrada has 79 hits along with 9 home runs and 47 RBIs while also chipping in 15 doubles. Michael Conforto has 101 hits with 20 home runs, 27 doubles, 20 home runs, and 66 RBIs while Matt Chapman has 139 hits of his own alongside 36 doubles with 27 homers, 78 RBIs, and 15 stolen bases. Chapman also has the dubious distinction of leading the Giants with 157 strikeouts this season. Heliot Ramos has 23 home runs and  72 RBIs and a .273 batting average as well this year.

Why the San Francisco Giants will win

• The Giants have won each of their last seven night games following a road loss.
• The Cardinals have lost five of their last six games at Oracle Park.
• The Giants have covered the run line in each of their last seven night games following a road loss.
• The Cardinals have failed to cover the run line each of their last five Friday games against National League opponents that held a losing record.

San Francisco Giants vs St. Louis Cardinals Prediction

I’m on the Giants here. Both of these teams are in solid form coming into this game, but I feel like I can trust the Giants slightly more in this spot being at home, and I’m just not a big Miles Mikolas fan if I’m being completely honest. The Cardinals have been playing well, but I like what I’ve seen from Roupp in a small sample size and I think there’s value in backing the Giants in this one. Give me San Francisco.