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Giants vs Rays Prediction 8/17/25 MLB Picks Today

Tampa Bay Rays (61-63) vs. San Francisco Giants (59-64)
August 17, 2025 4:05 pm EDT
The Line: San Francisco Giants -164 / Tampa Bay Rays +134; Over/Under: 7.5
(Get latest betting odds)

The Tampa Bay Rays and the San Francisco Giants meet Sunday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Giants vs Rays Prediction.

Starting Pitching Matchup

The Tampa Bay Rays will send out Ryan Pepiot for the start here and Pepiot is 8-9 with a 3.86 ERA and 138 strikeouts this season. This will be Pepiot’s second career start against San Francisco. The San Francisco Giants will trot out Logan Webb here and Webb is 10-9 with a 3.34 ERA and 168 strikeouts this season. This will be Webb’s second career start against the Rays.

Tampa Bay Rays Recap

The Tampa Bay Rays come into this game looking to add on to their 2-1 win over the Giants from Saturday’s matchup to sit at 61-63 on the year. After this series, the Rays will head home for a series against the New York Yankees.

Rays Win Three In A Row

Jonathan Aranda has 113 hits with 22 doubles, 12 home runs and 54 RBIs. Brandon Lowe has 103 hits with 24 homers and 59 RBIs as well while Junior Caminero has 119 hits with 21 doubles, a team-high 34 home runs and 84 RBIs. Yandy Diaz has 128 hits with 22 doubles, 20 homers and 67 RBIs.

Why the Tampa Bay Rays will win

  • The Giants have lost each of their last eight games as home favorites after playing the previous day.
  • The Rays have won each of their last six games as road underdogs against National League opponents following a win.
  • The Giants have failed to cover the run line in each of their last 11 games as home favorites after playing the previous day.
  • The Rays have covered the run line in each of their last seven games as road underdogs against National League opponents following a road win.

Tampa Bay Rays Player Prop Facts

  • Brandon Lowe has hit a home run in five of the Rays’ last 10 games.
  • Ha-Seong Kim has recorded at least one hit in each of his last eight road appearances against NL opponents that held a losing record.
  • Josh Lowe has recorded a Double in three of his last four appearances.
  • Chandler Simpson ranks T3rd in the league in Steals (34) this season.

San Francisco Giants Recap

The San Francisco Giants come into this one looking to rebound from their loss at the hands of the Rays in Saturday’s matchup, dropping to 59-64 on the year. After this series, the Giants will hit the road for a rematch series against the San Diego Padres.

Giants Drop 7th In A Row

Jung Hoo Lee has 111 hits including a team-high 27 doubles along with 10 triples, 6 home runs and 46 RBIs with 8 stolen bases while Heliot Ramos has 124 hits with 20 doubles, 14 home runs and 51 RBIs. Wilmer Flores also 12 home runs and 61 RBIs while Tyler Fitzgerald has a team-high 9 stolen bases as well on the year. Matt Chapman also has 79 hits with 16 home runs and 44 RBIs along with 15 doubles and Willy Adames has 100 hits with 18 doubles, 18 home runs and 61 RBIs of his own this season.

Why the San Francisco Giants will win

  • The Giants have won each of their last four day games against American League opponents following a home loss.
  • The Rays have lost four of their last five day games following a win.
  • The Rays have failed to cover the run line each of their last four day games against National League opponents that held a losing record.
  • The Giants have covered the run line in four of their last five games against the Rays following a loss.

San Francisco Giants Player Prop Facts

  • Rafael Devers has recorded a Double in three of the Giants’ last four games as favorites against AL opponents.
  • Willy Adames has hit at least one home run in each of his last three appearances with his team as a home favorite against the Rays.
  • Logan Webb has recorded six or more strikeouts in each of his last nine appearances against opponents that held a losing record.
  • Dominic Smith has recorded at least one hit in each of his last 11 appearances with the Giants as favorites.
  • Logan Webb ranks 5th in the league for total Strikeouts (168) this season.

Total Runs Facts

  • Eight of the Giants’ last nine day games against AL East opponents have gone OVER the total runs line.
  • Seven of the Rays’ last eight games against NL West opponents have gone UNDER the total runs line.

Giants vs Rays Prediction

I’m on the under in this one. Logan Webb has been far more effective at home this season, and I’m not trusting this Rays offense for much right now. On the other side, the Giants’ offense has been pretty non-existent in its own right. I feel like this is a spot for a low-scoring game and for this game to come in under the total. Give me the under here.

Chris Ruffolo's Free Pick: Under 7.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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