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Rangers vs Astros Prediction 9/5/25 MLB Picks Today

Houston Astros (77-64) vs. Texas Rangers (72-69)
September 5, 2025 8:05 pm EDT
The Line: Texas Rangers / Houston Astros ; Over/Under:
(Get latest betting odds)

The Houston Astros and the Texas Rangers meet Friday in MLB action from Globe Life Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Rangers vs Astros Prediction.

Starting Pitching Matchup

The Houston Astros did not have a starting pitcher announced at the time this article was posted. Merrill Kelly will get the nod for the Rangers here and is 11-7 with a 3.24 ERA and 149 strikeouts this season. In his career, Kelly is 0-1 with a 0.73 ERA and 11 strikeouts against the Astros.

Houston Astros Recap

The Houston Astros come into this game looking to rebound from an 8-4 loss at the hands of the New York Yankees last time out to sit at 77-64 on the year. After this series, the Astros will head on the road again for a series against the Toronto Blue Jays.

Astros Drop 4 Of Their Last 6

Jose Altuve has 141 hits including 21 doubles, 24 home runs and 69 RBIs. Jeremy Pena also has 133 hits with 26 doubles, 15 homers and 53 RBIs with 20 stolen bases as well. Jake Meyers has 15 doubles as well and Christian Walker has 21 home runs and 74 RBIs but has also accrued a team-high 152 strikeouts so far this season. Altuve also has 9 stolen bases while Jake Meyers has 14 stolen bases this season. Isaac Paredes also has 19 home runs with 50 RBIs of his own and Cam Smith has contributed 8 homers and 49 RBIs. Yainer Diaz has also chipped in 118 hits with 18 home runs, 56 RBIs and 19 doubles.

Why the Houston Astros will win

  • The Rangers have lost each of their last seven Friday home games against AL West opponents.
  • The Astros have won 10 of their last 12 road games against the Rangers following a loss.
  • The Astros have covered the run line in 10 of their last 11 road games against AL West opponents following a home loss.
  • The Rangers have failed to cover the run line in eight of their last nine home games against the Astros following a loss.

Houston Astros Player Prop Facts

  • Yordan Alvarez has hit a home run in four of his last five road appearances against the Rangers.
  • Jake Meyers has recorded at least one hit in each of his last 16 road appearances against AL opponents.

Texas Rangers Recap

The Texas Rangers come into this game looking to rebound from back-to-back losses after a 2-0 loss at the hands of the Arizona Diamondbacks last time out to sit at 72-69 this season. After this series, the Rangers will take on the Milwaukee Brewers in a series at home.

Rangers Drop Back-To-Back Games

Corey Seager has 103 hits including 21 home runs and 50 RBIs while Adolis Garcia has 112 hits with 28 doubles, 18 home runs, 73 RBIs and 13 stolen bases. Josh Jung has 102 hits with 16 doubles, 13 home runs and 53 RBIs while Wyatt Langford has 110 hits with 22 doubles, 21 home runs, 59 RBIs and 18 stolen bases and Jonah Heim has 10 homers and 41 RBIs. Josh Smith has chipped in 114 hits with 22 doubles, 9 home runs and 33 RBIs with 10 stolen bases and Marcus Semien’s added 108 hits with 16 doubles, 15 homers and 62 RBIs but has 93 strikeouts this season.

Why the Texas Rangers will win

  • The Rangers have won eight of their last nine games against American League opponents.
  • The Astros have lost six of their last seven night games against AL West opponents.
  • The Astros have failed to cover the run line in each of their last nine night games against AL West opponents following a home loss.
  • The Rangers have covered the run line in each of their last six home games against AL West opponents following a loss.

Texas Rangers Player Prop Facts

  • Merrill Kelly has recorded six or more strikeouts in six of his seven previous appearances against AL West opponents that held a winning record.
  • Corey Seager has hit a home run in four of the Rangers’ last five home games against AL West opponents.
  • Adolis Garcia has recorded at least one Double in three of the Rangers’ last four home games.
  • Josh Jung has recorded at least one hit in each of his last 14 appearances against AL West opponents.

Total Runs Facts

  • Four of the Astros’ last five road games have gone OVER the total runs line.
  • Four of the Rangers’ last five games against AL West opponents have gone OVER the total runs line.

Rangers vs Astros Prediction

I’m on the Rangers here. I just think right now the Rangers have the better upside, as Merrill Kelly is still one of the better arms the Rangers have going healthy right now. The Houston Astros have not been anything to write home about if you look at their form over the last week. It would be nice to know who they are sending out here, but I think Texas still gets it done in this one. Give me the Rangers.

Chris Ruffolo's Free Pick: Texas Rangers

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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