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Tigers vs Pirates Prediction 9/26/26 MLB Picks Today

Pittsburgh Pirates (81-79) vs. Detroit Tigers (75-85)
September 26, 2026 1:10 pm EDT
The Line: Detroit Tigers -123 / Pittsburgh Pirates 102; Over/Under: 8.5
(Get latest betting odds)

The Pittsburgh Pirates and Detroit Tigers meet Saturday in MLB action at Comerica Park. Here’s a Tigers vs. Pirates Prediction. This article will include a Tigers vs. Pirates Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 81-79 this year. The Pittsburgh Pirates are batting .253 on the season, with a .331 OBP and a .404 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.15 ERA and a 1.30 WHIP. Nick Gonzales leads the Pittsburgh Pirates with 164 hits and 60 RBI, while Bryan Reynolds and Brandon Lowe have combined for 304 hits and 165 RBI.

Kirby Yates gets the ball for the Pittsburgh Pirates, and he is 2-5 with a 3.32 ERA and 48 strikeouts this season. Yates is 2-1 with a 3.57 ERA and 23 strikeouts in his career against the Detroit Tigers.

Detroit Tigers Betting Preview

The Detroit Tigers are 75-85 on the year. The Detroit Tigers are batting .241 on the season and have a .320 OBP and a .400 slugging percentage. The Detroit Tigers’ pitching staff has a 3.65 ERA and a 1.22 WHIP. Kevin McGonigle leads the Detroit Tigers with 165 hits and 70 RBI, while Dillon Dingler and Riley Greene have combined for 273 hits and 164 RBI.

Justin Verlander gets the ball for the Detroit Tigers, and he is 0-1 with a 12.27 ERA and 1 strikeout this season. Verlander is 5-2 with a 3.08 ERA and 60 strikeouts in his career against the Pittsburgh Pirates.

Why the Detroit Tigers will win

  • The home team has won seven of the Pirates’ last eight games.
  • The Pirates have lost six of their last seven road games against AL Central opponents that held a losing record.
  • The Pirates have failed to cover the run line in seven of their last eight day games against teams that held a losing record.
  • The favorites have covered the run line in five of the Pirates’ last six games at Comerica Park.
  • The Tigers have won the first inning in each of their last three day games against NL Central opponents that held a winning record.
  • The Tigers have led after 3 innings in five of their last six games as favorites against NL Central opponents.
  • The Pirates have trailed after 5 innings in each of their last four road games.

Why the Pittsburgh Pirates will win

  • The Pirates have won each of their last 11 day games against AL opponents.
  • The Tigers have lost eight of their last nine day games against teams that held a winning record.
  • The Pirates have covered the run line in each of their last eight games as underdogs against AL opponents following a road loss.
  • The Tigers have failed to cover the run line in seven of their last eight games against NL Central opponents following a win.
  • The Pirates have led after 5 innings in six of their last seven road games against AL Central opponents.
  • The Tigers have trailed after 3 innings in four of their last five games against opponents that held a winning record.

Total Runs Facts

  • Each of the last seven games between the Pirates and Tigers at Comerica Park has gone OVER the total runs line.
  • Eight of the Pirates’ last nine games as underdogs against the Tigers have gone OVER the total runs line.
  • There has been no run scored during the first inning in 11 of the Pirates’ last 12 road games against AL Central opponents.
  • There has been at least one run scored in the first inning in each of Justin Verlander’s last four home appearances as a starter.

Detroit Tigers Player Prop Facts

  • Spencer Torkelson has hit a home run in six of the Tigers’ last seven games as favorites against NL Central opponents.
  • Riley Greene has recorded at least one hit in each of his last eight appearances with the Tigers as favorites against NL Central opponents.
  • Justin Verlander has recorded five or more strikeouts in each of his last 10 appearances at Comerica Park.
  • Justin Verlander has recorded a win in seven of his last eight appearances at Comerica Park.

Pittsburgh Pirates Player Prop Facts

  • Rafael Flores has hit at least one home run in three of his last four appearances against AL Central opponents that held a losing record.
  • Oneil Cruz has recorded at least one hit in each of his last 14 appearances with the Pirates as underdogs against AL Central opponents.
  • Nick Gonzales is one of only five players to hit over .300 and have 45+ RBIs this season.

Matchup/League Facts

  • The Tigers rank 29th in the league for steals this season (57).
  • The Tigers rank 4th in the league for triples this season (34).
  • The Pirates rank 2nd in the league for hits this season (1388).
  • The Pirates rank 2nd in the league for home runs allowed this season (152).

Tigers vs Pirates Prediction

The only angle in this spot is that it’s Verlander’s last game, and I’m sure the Tigers will want to send him home with a victory. The crowd will be packed, and there will be more energy than previously given; neither of these teams are playing for October. He hasn’t pitched since March, so who knows what to expect, but he’s a Hall of Famer who deserves to go out on top. Cheap price. I like the Tigers to get the nod for one of the best arms in the history of the sport.

Randy Chambers's Free Pick: Detroit Tigers -123

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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