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Tigers vs Red Sox Prediction 9/28/25 MLB Picks Today

Tigers vs Red Sox
September 28, 2025 3:05 pm EDT
The Line: Red Sox TBA / Over/Under: TBA
(Get latest betting odds)

In this article, we will formulate a Tigers vs Red Sox Prediction for this MLB game on Sunday, September 28th at the Fenway Park in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Boston Red Sox Preview

The Boston Red Sox have an 88-73 record this season and are sitting on the third place of the AL East. The Red Sox have a 47-33 home record and are 76-81 in over/under. They are coming off a 1-2 home defeat by the Tigers, and under is 4-1 in their last 5 games.


The Red Sox have a .254 batting average this season, .323 OBP and .421 slugging percentage. Boston’s pitching staff has a 3.71 ERA and 1.29 WHIP. Trevor Story leads the Red Sox with 161 hits, while is the team’s best hitter, with a .265 batting average. He also leads the team in RBI, with 96, adding a team-high 25 home runs.

The Red Sox have not announced a starting pitcher for this game yet.

Detroit Tigers Preview

The Detroit Tigers have an 87-74 record this season and are sitting on the first place of the AL Central. The Tigers have a 41-39 road record and are 83-70 in over/under. They are coming off a 2-1 road win over the Red Sox, but still are 2-9 in their last 11 games. Under is 5-1 in their last 6 games.

The Tigers have a .247 batting average this season, .316 OBP and .414 slugging percentage. Detroit’s pitching staff has a 3.94 ERA and 1.25 WHIP. Riley Greene leads the Tigers with 155 hits, adding team-highs both in RBI, with 111, and in home runs, with 36. Zach McKinstry is the team’s best hitter with a .261 batting average.

Chris Paddack (R) is the projected starter for the Tigers, and he has a 5-11 record, 5.27 ERA and 1.25 WHIP.

Detroit Tigers @ Boston Red Sox Betting Trends: September 28, 2025

 

  • Probable Starting Pitcher: TBD

Why the Boston Red Sox will win

  • The Tigers have lost each of their last seven road games against the Red Sox following a win.
  • The Red Sox have won each of their last six games against the Tigers following a home loss.
  • The Red Sox have covered the run line in each of their last six games against the Tigers following a home loss.
  • The Tigers have failed to cover the run line in six of their last seven road games against the Red Sox following a win.
  • The Red Sox have led after 3 innings in each of their last four day games against the Tigers at Fenway Park.
  • The Red Sox have led after 5 innings in 11 of their last 13 day games at Fenway Park against AL Central opponents.

 

  • Probable Starting Pitcher: Chris Paddack      Record this season: 5-11      ERA: 5.27
  • Road Record: 2-6
  • Last 5 against Red Sox: 1-1

Why the Detroit Tigers will win

  • The Tigers have won each of their last eight Sunday games against AL East opponents.
  • The Red Sox have lost each of their last four day games against American League opponents.
  • The Tigers have covered the run line in each of their last 10 Sunday day games against AL East opponents.
  • The Red Sox have failed to cover the run line in eight of their last nine home games.
  • The Red Sox have lost the first inning in three of their last four day games.
  • The Tigers have led after 3 innings in six of their last eight day games against AL East opponents.
  • The Red Sox have trailed after 5 innings in each of their last five day games.

Total Runs Facts

  • Each of the Tigers’ last five road games after playing the previous day have gone UNDER the total runs line.
  • Each of the Red Sox’s last four day games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in 15 of the Tigers’ last 17 day games against AL East opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Red Sox’s last six day games against American League opponents.

Boston Red Sox Player Prop Facts

  • Trevor Story has recorded a Double in three of his last four appearances in day games.
  • Alex Bregman has hit a home run in two of his last three appearances against the Tigers.
  • Alex Bregman has recorded at least one hit in 15 of his last 16 appearances in day games against AL Central teams that held a winning record.

Detroit Tigers Player Prop Facts

  • Javier Baez has recorded at least one hit in each of his last nine road appearances against AL East opponents.
  • Gleyber Torres has hit a home run in four of his last nine appearances in day games against AL East teams that held a winning record.

Matchup/League Facts

  • The Red Sox rank 1st in the league for doubles this season (320).
  • The Red Sox rank 4th in the league for hits this season (1407).
  • The Tigers rank 30th in the league for steals this season (60).
  • The Tigers rank 3rd in the league for triples this season (36).

Tigers vs Red Sox Prediction

The Tigers are 6-1 in their last 7 meetings against the Red Sox, and both teams are tied 3-3 wins in their last 6 meetings in Boston.

The Tigers cliched their playoff spot with yesterday’s win, so both teams have nothing to play for. The Red Sox have not announced a starter yet, and the Tigers are sending Chris Paddack on the mound, who has been mediocre at best this season, and coming into this matchup in terrible form, with a 6.38 ERA across his last 5 starts. In his only start against the Red Sox this season, he gave up 3 runs, and I don’t think the Tigers will have too much interested in winning this one. Take the Red Sox to bounce back and win at home in the regular season finale.

Nikos Lagouretos's Free Pick: Boston Red Sox ML

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