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Toronto Blue Jays vs Cincinnati Reds Prediction 9/27/26 MLB Picks Today

Cincinnati Reds (75-86) vs. Toronto Blue Jays (78-83)
September 27, 2026 3:07 pm EDT
The Line: Toronto Blue Jays -181 / Cincinnati Reds +149; Over/Under: 8.5
(Get latest betting odds)

The Cincinnati Reds and the Toronto Blue Jays meet Sunday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

The Cincinnati Reds will send out Brandon Williamson for the start here and Williamson is 5-4 with a 4.89 ERA and 32 strikeouts this season. Max Scherzer will go for Toronto and is 3-9 with a 6.14 ERA and 61 strikeouts this season.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to add on to their 5-1 win over Toronto last time out to improve to 75-86 this season.

Reds Alternate Wins & Losses In 6 Straight

Sal Stewart leads the Reds across the board in hits, home runs, and RBIs with a team-high 162 hits, 32 home runs, and 110 RBIs while adding 25 doubles so far this season. Elly De La Cruz has added 156 hits with 29 doubles, 5 triples, 30 home runs, and 77 RBIs, while JJ Bleday has logged 98 hits with 16 doubles, 2 triples, 23 home runs, and 57 RBIs on the year. Spencer Steer has contributed 81 hits with 14 doubles, 16 home runs, and 40 RBIs. Matt McLain has chipped in 81 hits with 18 doubles, a triple, 15 home runs, and 40 RBIs for Cincinnati up to this point in the season.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to rebound from their loss to Cincinnati on Saturday to sit at 78-83 this season.

Blue Jays Drop 7 Of Last 10

Ernie Clement leads the Blue Jays with a team-high 153 hits while adding 33 doubles, a triple, 9 home runs, and 48 RBIs so far this season. Kazuma Okamoto leads Toronto with a team-high 33 home runs and 89 RBIs alongside 130 hits and 24 doubles on the year. Vladimir Guerrero Jr. has contributed 140 hits with 25 doubles, 9 home runs, and 56 RBIs, while Andres Gimenez has logged 113 hits with 25 doubles, a triple, 9 home runs, and 58 RBIs. George Springer has added 114 hits with 22 doubles, 2 triples, 15 home runs, and 54 RBIs for Toronto up to this point in the season.

Cincinnati Reds @ Toronto Blue Jays Betting Trends: September 27, 2026

 

  • Probable Starting Pitcher: Max Scherzer      Record this season: 3-9      ERA: 6.14
  • Home Record: 3-7
  • Last 5 against Reds: 3-1

Why the Toronto Blue Jays will win

  • The Reds have lost each of their last six games following a win.
  • The Blue Jays have won 10 of their last 11 day games following a loss.
  • The Blue Jays have covered the run line in nine of their last 10 day games against NL opponents following a loss.
  • The Reds have failed to cover the run line in six of their last seven games against AL opponents following a win.
  • The Reds have lost the first inning in four of their last five games at Rogers Centre.
  • The Blue Jays have led after 5 innings in four of their last five home day games.
  • The Reds have trailed after 3 innings in three of their last four day games.

 

  • Probable Starting Pitcher: Brandon Williamson      Record this season: 5-4      ERA: 4.89
  • Road Record: 4-2
  • Last 5 against Blue Jays: 0-1

Why the Cincinnati Reds will win

  • The Blue Jays have lost four of their last five games as favorites after playing the previous day.
  • The Reds have won seven of their last eight day games against AL opponents.
  • The road team has covered the run line in each of the Reds’ last seven games.
  • The Blue Jays have failed to cover the run line each of their last six games against teams that held a losing record.
  • The Blue Jays have trailed after 3 innings in each of their last four games.
  • The Reds have led after 5 innings in each of their last five day games against AL opponents that held a losing record.

Total Runs Facts

  • Eight of the last nine games between the Reds and Blue Jays have gone OVER the total runs line.
  • Six of the Reds’ last seven games as underdogs against the Blue Jays have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in nine of Max Scherzer’s last 10 home appearances as a starter.
  • There has been no run scored during the first inning in each of Brandon Williamson’s last five road appearances as a starter.

Toronto Blue Jays Player Prop Facts

  • George Springer has hit at least one home run in three of his last four appearances with the Blue Jays as favorites against the Reds.
  • Max Scherzer has recorded a win in six of his last eight appearances against the Reds.
  • Max Scherzer has recorded six or more strikeouts in 22 of his last 23 appearances in day games against NL teams that held a losing record.
  • George Springer has recorded at least one hit in each of his last seven appearances in day games against NL Central teams that held a losing record.

Cincinnati Reds Player Prop Facts

  • JJ Bleday has hit a home run in each of the Reds’ last two day games.
  • Eugenio Suarez has recorded at least one hit in each of his last 10 appearances against the Blue Jays.
  • Elly De La Cruz ranks 10th amongst qualified players for Slugging Percentage (.517) this season.

Matchup/League Facts

  • The Blue Jays rank 30th in the league for runs scored this season (643).
  • The Blue Jays rank 30th in the league for home runs this season (150).
  • The Reds rank 30th in the league for hits this season (1224).
  • The Reds rank 30th in the league for batting average this season (.229).

Cincinnati Reds vs. Toronto Blue Jays Prediction

I’m on the Reds in this one. I just think that Toronto’s struggled against lefties for the better part of the season and while Toronto would like to end the season on a high after a disappointment to the fans after coming two outs shy of winning a World Series last year, I just don’t see it. I think Scherzer gets hit to round out the year and Cincinnati gets the win to close out the season. Give me Cincinnati.

Chris Ruffolo's Free Pick: Cincinnati Reds +149

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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