Twins vs Angels Prediction 4/25/25 MLB Picks Today

The Los Angeles Angels and Minnesota Twins meet Friday in MLB action at Target Field. Here’s a Twins vs Angels Prediction. This article will include a Twins vs Angels Pick.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 12-12 on the year and play the Mariners, Tigers, and Blue Jays next. The Los Angeles Angels are batting .215 on the season, have a .272 OBP, and a .398 slugging percentage. The Los Angeles Angels pitching staff has a 4.44 ERA and a 1.42 WHIP. Nolan Schanuel leads the Los Angeles Angels with 22 hits and 8 RBI, while Jorge Soler and Taylor Ward have combined for 43 hits and 19 RBI.

Kyle Hendricks gets the ball for the Los Angeles Angels, and he is 0-2 with a 4.50 ERA and 10 strikeouts this season. Hendricks is 1-3 with a 4.01 ERA and 19 strikeouts in his career against the Minnesota Twins.

Minnesota Twins Betting Preview

The Minnesota Twins are 9-16 on the year and play the Guardians, Red Sox, and Orioles next. The Minnesota Twins are batting .216 on the season, have a .293 OBP, and a .347 slugging percentage. The Minnesota Twins pitching staff has a 3.89 ERA and a 1.26 WHIP. Ty France leads the Minnesota Twins with 20 hits and 12 RBI while Byron Buxton and Trevor Larnach have combined for 37 hits and 21 RBI.

Pablo Lopez gets the ball for the Minnesota Twins, and he is 1-1 with a 1.62 ERA and 14 strikeouts this season. Lopez is 3-1 with a 3.38 ERA and 34 strikeouts in his career against the Los Angeles Angels.

Why the Minnesota Twins will win

• The Angels have lost 10 of their last 11 night games against American League opponents following a win.
• The Twins have won seven of their last eight home games against AL West opponents following a home loss.
• The Angels have failed to cover the run line in each of their last eight road games against AL Central opponents.
• The Twins have covered the run line in seven of their last eight home games against AL West opponents following a home loss.
• The Angels have lost the first inning in three of their last four games at Target Field against American League opponents that held a losing record.
• The Twins have led after 5 innings in five of their last six games against the Angels.
• The Angels have trailed after 3 innings in each of their last four night games.

Why the Los Angeles Angels will win

• The Angels have won eight of their last nine games as underdogs against AL Central opponents following a home win.
• The Twins have lost 10 of their last 13 games as home favorites after playing the previous day.
• The underdogs have covered the run line in each of the Angels’ last six games.
• The Twins have failed to cover the run line in 11 of their last 13 games as home favorites after playing the previous day.
• The Twins have trailed after 3 innings in three of their last four night games against AL West opponents.
• The Angels have won the first inning in three of their last four road games against American League opponents that held a losing record.

Minnesota Twins Player Prop Facts

• Trevor Larnach has hit a home run in three of the Twins’ last four night games.
• Ryan Jeffers has recorded at least one RBI in five of his last six appearances against the Angels.
• Pablo Lopez has recorded a win in four of his last five home appearances.
• Pablo Lopez has recorded seven or more strikeouts in each of his four previous appearances against the Angels.
• Byron Buxton has scored at least one run in each of his last seven home appearances against AL West opponents.
• Christian Vazquez has recorded at least one Single in each of his last four appearances against the Angels.
• Willi Castro has recorded at least one hit in each of his last 17 appearances against the Angels.

Los Angeles Angels Player Prop Facts

• Logan O’Hoppe has hit a home run in four of his last five appearances against AL Central opponents.
• Kyle Hendricks has recorded a win in three of his last four road appearances against AL Central opponents that held a losing record.
• Mike Trout has recorded at least one RBI in each of his last four road appearances against the Twins.
• Taylor Ward has scored at least one run in seven of the Angels’ last eight games against opponents that held a losing record.
• Nolan Schanuel has recorded at least one Single in each of his eight previous appearances against the Twins.
• Taylor Ward has recorded at least one hit in each of the Angels’ last 14 road games against AL Central opponents.
• Kyle Hendricks has recorded three or more strikeouts in 17 of his last 18 appearances against AL Central opponents.
• Yoan Moncada has recorded a Double in each of his last three appearances at Target Field.
• Mike Trout ranks T4th in the league in Home Runs (8) this season.

Twins vs Angels Prediction

The Twins haven’t played well enough to lay these sorts of prices, but I’m backing them anyway. The Angels haven’t won two straight games in three weeks, and the offense continues to come up small as of late. Hendricks hasn’t really been good over these last three or four years, and he’s off to a shaky start this season.

Lopez is coming off a hamstring injury and will pitch for the first time in 17 days, but he’s an all-star pitcher who has allowed just three earned runs in 16.2 innings. Lopez feels like the guy who can get the Twins a much-needed win and stop the bleeding a bit. Of course, I’m laying the RL to shave down the juice.