
Twins vs Astros Prediction 4/5/25 MLB Picks Today
Houston Astros (3-4) vs. Minnesota Twins (2-5)
April 5, 2025 2:10 pm EDT
The Line: Minnesota Twins -125 / Houston Astros 105; Over/Under: 7.5
(Get latest betting odds)
The Houston Astros and Minnesota Twins meet on Saturday in MLB action at Target Field. Here’s a Twins vs Astros Prediction. This article will include a Twins vs Astros Pick.
Houston Astros Betting Preview
The Houston Astros are 3-4 on the year and play the Mariners, Angels, and Cardinals next. The Houston Astros are batting .191 on the season, have a .274 OBP, and a .270 slugging percentage. The Houston Astros’ pitching staff has a 3.14 ERA and a 1.00 WHIP. Jose Altuve leads the Houston Astros with 9 hits and 1 RBI, while Brendan Rodgers and Christian Walker have combined for 10 hits and 4 RBI.
Spencer Arrighetti gets the ball for the Houston Astros, and he is 1-0 with a 1.50 ERA and 5 strikeouts this season. This will be Arrighetti’s second career game against the Minnesota Twins.
Minnesota Twins Betting Preview
The Minnesota Twins are 2-5 on the year and play the Royals, Tigers, and Mets next. The Minnesota Twins are batting .180 on the season, have a .240 OBP, and a .294 slugging percentage. The Minnesota Twins’ pitching staff has a 5.34 ERA and a 1.37 WHIP. Byron Buxton leads the Minnesota Twins with 6 hits and 3 RBI, while Willi Castro and Ty France have combined for 11 hits and 5 RBI.
Bailey Ober gets the ball for the Minnesota Twins, and he is 0-1 with a 27.00 ERA and 3 strikeouts this season. Ober is 0-0 with a 4.50 ERA and 12 strikeouts in his career against the Houston Astros.
Why the Minnesota Twins will win
- The Twins have won each of their last five day games against AL West opponents following a loss.
- The Astros have lost five of their last six games following a win.
- The Twins have covered the run line in each of their last four home games against AL West opponents following a home loss.
- The Astros have failed to cover the run line in five of their last six games.
Why the Houston Astros will win
- The Twins have lost seven of their last eight games as favorites following a loss.
- The Astros have won each of their last seven road games against American League opponents that held a losing record.
- The Astros have covered the run line in each of their last eight road games against American League opponents.
- The Twins have failed to cover the run line in eight of their last nine day games against American League opponents.
- The Twins have trailed after 5 innings in nine of their last 10 games as favorites against American League opponents.
- The Twins have trailed after 3 innings in three of their last four games at Target Field against opponents that held a losing record.
Twins vs Astros Prediction
While the talent suggests that these teams are better than what they’ve shown up to this point, the Astros and Twins are two of the worst offensive teams in baseball. The Twins have scored three or fewer runs in five of their seven games, while the Astros have scored three or fewer runs in six of their seven games. The Twins and Astros are hitting under 200 on the season, and they’ve combined for 88 strikeouts. While things should improve eventually, I’m going to side with the under in this spot based on the way neither team is hitting the ball.