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Twins vs Orioles Prediction 5/7/25 MLB Picks Today

Baltimore Orioles (13-21) vs. Minnesota Twins (16-20)
May 7, 2025 7:40 pm EDT
The Line: Minnesota Twins -142 / Baltimore Orioles 120; Over/Under: 9.5
(Get latest betting odds)

The Baltimore Orioles and Minnesota Twins meet Wednesday in MLB action at Target Field. Here’s a Twins vs Orioles Prediction. This article will include a Twins vs Orioles Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 13-21 on the year and play the Angels, Twins, and Nationals next. The Baltimore Orioles are batting .223 on the season, have a .294 OBP, and a .383 slugging percentage. The Baltimore Orioles pitching staff has a 5.49 ERA and a 1.54 WHIP. Cedric Mullins leads the Baltimore Orioles with 28 hits and 21 RBI, while Gunnar Henderson and Ryan O’Hearn have combined for 53 hits and 19 RBI.

Charlie Morton gets the ball for the Baltimore Orioles, and he is 0-6 with a 9.76 ERA and 26 strikeouts this season. Morton is 2-1 with a 4.50 ERA and 28 strikeouts in his career against the Minnesota Twins.

Minnesota Twins Betting Preview

The Minnesota Twins are 16-20 on the year and play the Giants, Orioles, and Brewers next. The Minnesota Twins are batting .237 on the season, have a .306 OBP, and a .372 slugging percentage. The Minnesota Twins pitching staff has a 3.53 ERA and a 1.20 WHIP. Byron Buxton leads the Minnesota Twins with 35 hits and 22 RBI, while Ty France and Carlos Correa have combined for 63 hits and 31 RBI.

Simeon Woods Richardson gets the ball for the Minnesota Twins, and he is 2-2 with a 4.03 ERA and 30 strikeouts this season. This will be Woods Richardson’s first career game against the Baltimore Orioles.

Why the Minnesota Twins will win

  • The Orioles have lost each of their last nine games at Target Field against AL Central opponents that held a losing record.
  • The Twins have won eight of their last nine games at Target Field.
  • The Orioles have failed to cover the run line in 10 of their last 11 night games against teams that held a losing record.
  • The Twins have covered the run line in seven of their last eight home games against American League opponents.
  • The Twins have won the first inning in three of their last four games against opponents that held a winning record at Target Field.
  • The Orioles have trailed after 3 innings in each of their last eight road games.
  • The Orioles have trailed after 5 innings in 10 of their last 11 night games against opponents that held a losing record.

Why the Baltimore Orioles will win

  • The Orioles have won eight of their last nine games as underdogs against the Twins.
  • The Twins have lost five of their last six games as favorites against AL East opponents.
  • The Orioles have covered the run line in 12 of their last 13 games as underdogs against the Twins.
  • The Twins have failed to cover the run line in each of their last five games as favorites against AL East opponents following a home win.
  • The Orioles have led after 3 innings in four of their last five night games against the Twins.
  • The Orioles have led after 5 innings in eight of their last nine games against the Twins.

Minnesota Twins Player Prop Facts

  • Ty France has recorded a Double in four of the Twins’ last five games as favorites against AL opponents.
  • Byron Buxton has hit a home run in each of the Twins’ last two games against AL East opponents.
  • Willi Castro has recorded an RBI in four of his last five appearances in night games against AL teams that held a losing record.
  • Willi Castro has recorded at least one Single in seven of his last eight home appearances against AL opponents.
  • Trevor Larnach has scored at least one run in eight of his last nine appearances in night games against AL teams that held a losing record.
  • Byron Buxton has recorded at least one hit in each of his last 10 appearances against AL East opponents.

Baltimore Orioles Player Prop Facts

  • Gunnar Henderson has hit a home run in three of his last four appearances against the Twins after playing the previous day.
  • Ryan Mountcastle has recorded a Double in three of his last four appearances in night games against AL Central teams that held a losing record.
  • Gunnar Henderson has recorded at least one RBI in each of his last six appearances against the Twins after playing the previous day.
  • Adley Rutschman has recorded at least one Single in eight of the Orioles’ last nine night games against AL Central opponents that held a losing record.
  • Ramon Laureano has recorded at least one hit in each of his last 16 appearances in night games against teams that held a losing record.
  • Gunnar Henderson has scored at least one run in seven of the Orioles’ last eight night games against AL Central opponents that held a losing record.
  • Charlie Morton has recorded four or more strikeouts in each of his last 11 appearances against AL Central opponents that held a losing record.
  • Charlie Morton has recorded a win in three of his last four appearances against AL Central opponents that held a losing record.

Twins vs Orioles Prediction

While the season is still fairly young, it might be time to say the Orioles aren’t a good team. The Orioles have lost 10 of their last 13 games, and a lot of these contests aren’t competitive. Morton doesn’t provide much hope when he’s allowed 40 hits and 30 earned runs in 27.2 innings. Morton also has 21 walks to go with 26 strikeouts. At 41 years old, it’s probably fair to say Morton is washed up and probably just an innings-eater at this point.

The Twins are having a nice week with three straight wins, and Woods Richardson has been respectable, especially at home, where he has a 1.74 ERA and .225 allowed batting average in 10.1 innings. I’m not getting the warm and fuzzy vibes from the Orioles. Give me the Twins and the reasonable price.

Randy Chambers's Free Pick: Minnesota Twins -142

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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