
Nationals vs Reds Prediction 7-22-25 MLB Picks
Cincinnati Reds (52-49) vs. Washington Nationals (40-60)
July 22, 2025 10:45 pm EDT
The Line: Washington Nationals +112 / Cincinnati Reds -136; Over/Under: 9
(Get latest betting odds)
The Cincinnati Reds and the Washington Nationals meet Tuesday in MLB action from Nationals Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Nationals vs Reds Prediction.
Starting Pitching Matchup
The Cincinnati Reds will send out Chase Burns for the start here and Burns is 0-1 with a 6.19 ERA and 25 strikeouts this season. This will be Burns’ first career start against the Nationals. Brad Lord will get the start for the Nationals here and Lord is 2-5 with a 3.46 ERA and 56 strikeouts this season. This will be Lord’s first career start against the Reds.
Cincinnati Reds Recap
The Cincinnati Reds come into this game looking to bounce back from a 10-8 loss at the hands of the Nationals last time out to sit at 52-49 on the year. After this series, the Reds will head home for a series against the Tampa Bay Rays.
Reds Drop Back-To-Back Games
Elly De La Cruz has 107 hits with 18 home runs, 65 RBIs, 18 doubles and 25 stolen bases while TJ Friedl has 97 hits with 15 doubles, 9 home runs and 33 RBIs with 10 stolen bases. Gavin Lux has added 73 hits with 17 doubles and 37 RBIs while Spencer Steer has 11 home runs and 40 RBIs and Matt McLain has added 11 homers, 35 RBIs and 14 stolen bases as well on the year. Jose Trevino’s also chipped in 17 doubles as well this season.
Why the Cincinnati Reds will win
- The Nationals have lost each of their last seven games against National League opponents following a win.
- The Reds have won three of their last four night games against NL East opponents.
- The Nationals have failed to cover the run line in each of their last six games as underdogs against NL Central opponents following a win.
- The Reds have covered the run line in five of their last six games against NL East opponents.
Cincinnati Reds Player Prop Facts
- TJ Friedl has recorded at least one hit in each of his last 11 appearances with the Reds as road favorites against NL East opponents.
- Jose Trevino has recorded a Double in four of his last five road appearances after playing the previous day.
- Jose Trevino has hit a home run in three of his last nine appearances after playing the previous day.
- Elly De La Cruz ranks 7th in the league in Steals (26) this season.
Washington Nationals Recap
The Washington Nationals come into this game looking to add on to their win over the Reds from Monday’s matchup to improve to 40-60 on the year. After this series, the Nationals will head on the road for a series against the Minnesota Twins.
Nationals Looking To Build Some Steam
Keibert Ruiz has 63 hits with 12 doubles and a pair of home runs with 25 RBIs while James Wood has 100 hits with 19 doubles and a team-high 24 home runs along with 69 RBIs and 13 stolen bases while also putting up 121 strikeouts. Nathaniel Lowe has 86 hits with 14 doubles and 62 RBIs along with 15 home runs and 113 strikeouts. CJ Abrams has 13 home runs and 36 RBIs along with 21 doubles and 20 stolen bases while Luis Garcia Jr. has 20 doubles and 8 stolen bases of his own this season. Dylan Crews has also logged 11 stolen bases as well this season.
Why the Washington Nationals will win
- The Nationals have won four of their last five games as underdogs against the Reds.
- The Reds have lost each of their last four games as road favorites against the Nationals following a loss.
- The Nationals have covered the run line in eight of their last nine games against the Reds.
- The Reds have failed to cover the run line in each of their last six games against the Nationals following a loss.
Washington Nationals Player Prop Facts
- Josh Bell has hit a home run in three of his last four appearances with his team as an underdog against the Reds.
- Amed Rosario has recorded at least one hit in 19 of his last 20 appearances at Nationals Park against opponents that held a winning record.
- Josh Bell has recorded a Double in five of the Nationals’ last six night games against NL Central opponents that held a winning record.
- James Wood ranks T10th in the league in Home Runs (24) this season.
Total Runs Facts
- Nine of the Nationals’ last 10 home games have gone OVER the total runs line.
- Seven of the Reds’ last eight games as favorites against the Nationals have gone OVER the total runs line.
Nationals vs Reds Prediction
I’m leaning towards the Reds here. I don’t love this matchup, but I think that Chase Burns is still a solid option for the Reds and this rotation. The only concern for Burns and that ERA has been plagued by one bad outing and I think that he bounces back here. On the other side, I’m not trusting the Nationals to have sustained success in this matchup, and I think the Reds exact some revenge here. Give me Cincinnati.