White Sox vs Astros Prediction 5/3/25 MLB Picks Today

In this article we will formulate a White Sox vs Astros prediction for this MLB game on Saturday, May 3rd at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 9-23 this year after they won game one by a score of 7-3 on Friday night. Chicago led 4-1 in the fifth inning, and they added three insurance runs in the eighth to seal the victory. The White Sox recorded nine hits and they committed two errors in the game, while they were led by Quero, who went 2-3 with two RBIs in the win. Chicago started Cannon, who allowed nine hits and two earned runs over 6.0 innings for the win, while Leasure allowed one hit and one earned run in the eighth. 

Prior to this series, the White Sox lost two out of three against the Brewers and two out of three against the Athletics. Chicago has split their last six games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.01 ERA with a 1.35 WHIP and a .236 opponent batting average, while the offense has scored 116 runs with a .216 batting average and a .294 on-base percentage this season. Luis Robert has led Chicago with five home runs and 14 RBIs, while Andrew Benintendi has added five home runs and 11 RBIs this year. The projected starting pitcher for Chicago is Davis Martin, who is 1-3 with a 3.24 ERA and a 1.32 WHIP over 33.1 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 16-15 this season after they lost game one on Friday night. Houston cut the deficit to 2-1 and 4-3, but their bullpen fell apart in the eighth for the loss. The Astros recorded 10 hits in the game, and they were led by Diaz, who went 3-4 with one home run and two RBIs in the game. Houston started Valdez, who allowed seven hits and four earned runs over 5.0 innings for the loss, while Scott allowed one hit and three earned runs over 1.1 relief innings. 

Prior to this series, the Astros won two out of three against the Tigers, but did lose two out of three against the Royals before that. Houston has won three of their last five games, and they are currently third in the AL West standings. The Houston pitching staff has a 3.36 ERA with a 1.10 WHIP and a .215 opponent batting average, while their offense has scored 120 runs with a .238 batting average and a .310 on-base percentage this season. Isaac Paredes has led Houston with four home runs and 14 RBIs, while Yordan Alvarez has added three home runs, 18 RBIs, and one stolen base this year. The projected starting pitcher for Houston is Hunter Brown, who is 4-1 with a 1.22 ERA and a 0.84 WHIP over 37.0 innings pitched this season. 

Why the White Sox will beat the Astros

• The Astros have lost four of their last five games as road favorites.
• The White Sox have won five of their last six games as underdogs against AL West opponents following a home win.
• The White Sox have covered the run line in each of their last eight day games against AL West opponents following a win.
• The Astros have failed to cover the run line each of their last six games against teams that held a losing record.
• The Astros have trailed after 5 innings in eight of their last nine games against AL Central opponents.
• The Astros have trailed after 3 innings in each of their last four games.
• The White Sox have won the first inning in each of their last three games against opponents that held a winning record.

Why the Astros will beat the White Sox

• The Astros have won nine of their last 10 games following a road loss.
• The White Sox have lost 12 of their last 14 home games against American League opponents that held a winning record.
• The Astros have covered the run line in each of their last eight day games against American League opponents following a road loss.
• The White Sox have failed to cover the run line in five of their last six home games against American League opponents that held a winning record.
• The Astros have led after 3 innings in each of their last four day games against the White Sox at Rate Field.
• The Astros have led after 5 innings in 13 of their last 16 games as road favorites against American League opponents.

Total Runs Facts

• Each of the Astros’ last five games against AL Central opponents have gone OVER the total runs line.
• Six of the last seven games between the Astros and White Sox at Rate Field have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last six games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last six Saturday games against American League opponents.

Chicago White Sox Player Prop Facts

• Luis Robert has hit a home run in four of the White Sox’s last seven home games against the Astros.
• Luis Robert has recorded at least one RBI in five of the White Sox’s last six games.
• Luis Robert has recorded at least one hit in each of the White Sox’s last seven games as underdogs.
• Josh Rojas has scored at least one run in five of his last six appearances at Rate Field.
• Austin Slater has recorded at least one Single in each of his last five appearances with his team as an underdog against the Astros.

Houston Astros Player Prop Facts

• Yainer Diaz has hit a home run in each of the Astros’ last two games as road favorites.
• Yordan Alvarez has recorded at least one RBI in 10 of his last 11 appearances with the Astros as favorites against the White Sox.
• Yordan Alvarez has recorded at least one hit in each of his last eight appearances against the White Sox after playing the previous day.
• Jeremy Pena has recorded at least one Single in 14 of the Astros’ last 15 games against AL opponents.
• Jose Altuve has scored at least one run in six of his last seven appearances against the White Sox after playing the previous day.
• Christian Walker has recorded a Double in three of the Astros’ last four games against AL Central opponents that held a losing record.

White Sox vs Astros Prediction 

Chicago is currently on a rare winning streak, after getting the win in game one of this series, and they do play their best baseball at home, where they are 6-10. The White Sox have started to play slightly better over the last week, and they will start Martin, who has allowed one earned run or fewer in three of his last four starts. Houston had some momentum coming into this series, but they are just 5-8 on the road. The Astros will start Hunter Brown, who has allowed a total of one earned run over his last four starts. Take the under here.