White Sox vs Athletics Prediction 4/17/25 MLB Picks Today

The Athletics and the Chicago White Sox meet Thursday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an White Sox vs Athletics Prediction.

Starting Pitching Matchup

The Athletics will send out JP Sears for the start here and Sears is 1-2 with a 4.24 ERA and 16 strikeouts this season. In his career, Sears is 1-3 with a 7.29 ERA and 19 strikeouts against the White Sox. The Chicago White Sox will trot out Davis Martin for the start here and Martin is 1-1 with a 4.24 ERA and 10 strikeouts this season. This will be Martin’s second career start against the Athletics.

Athletics Recap

The Athletics come into this game looking to complete the sweep of the White Sox after a 3-1 win in Wednesday’s matchup. After this series, the Athletics will head on the road for an interleague series against the Milwaukee Brewers.

Athletics Win Back-To-Back Games

Jacob Wilson leads the Athletics with 22 hits, 4 doubles and a .333 batting average while Tyler Soderstrom has 21 hits with 8 home runs and 17 RBIs this season. Brent Rooker has 15 hits with 4 home runs and 8 RBIs but also has a team-high 22 strikeouts this season while Max Muncy has 16 strikeouts. Lawrence Butler’s also chipped in a pair of stolen bases and 4 doubles as part of his 18 hits.

Why the Athletics will win

• The White Sox have lost each of their last eight day games against AL West opponents following a loss.
• The Athletics have won each of their last 12 Thursday day games as road favorites against American League opponents.
• The Athletics have covered the run line in seven of their last eight road games.
• The White Sox have failed to cover the run line in five of their last six home games against teams that held a losing record.

Chicago White Sox Recap

The Chicago White Sox will try to salvage something from the series after their loss in Wednesday’s matchup which handed the Pale Hose another series loss to start the year. After this series, the White Sox will head on the road for a series against the Boston Red Sox.

White Sox Lose Three In A Row

Lenyn Sosa leads the White Sox with 12 hits including a pair of doubles and 5 RBIs. Andrew Benintendi has 9 hits including 2 home runs, 6 RBIs and a .290 batting average while Miguel Vargas has a team-high 4 doubles and 6 RBIs. Brooks Baldwin has also added 7 RBIs while Luis Robert Jr. has a team-high 6 stolen bases so far this season. Nick Maton also has a pair of home runs for the White Sox while Andrew Vaughn has a team-high 2 home runs and 8 RBIs as well this season.

Why the Chicago White Sox will win

• The Athletics have lost six of their last seven games as favorites against AL Central opponents following a win.
• The White Sox have won three of their last four Thursday games as home underdogs.
• The White Sox have covered the run line in each of their last seven day games against AL West opponents.
• The Athletics have failed to cover the run line in six of their last seven games as favorites against AL Central opponents following a win.

Total Runs Facts

• Nine of the White Sox’s last 10 day games against AL West opponents have gone UNDER the total runs line.
• Each of the Athletics’ last four games after playing the previous day have gone UNDER the total runs line.

White Sox vs Athletics Prediction

I’m on the Athletics in this one. I know Sears has had issues dealing with this White Sox lineup in his career to this point, but I keep saying it. The White Sox just look like they’re in peak midseason White Sox form less than 20 games into the season, struggling to find offense and letting games get away from them. Davis Martin is a decent option, but the Athletics are smacking right-handed pitching right now and in all honesty, they’re not a team I want to get in front of against inferior lineups like Chicago’s. Give me the Athletics in this one.