White Sox vs Diamondbacks Prediction 6/23/25 MLB Picks Today

The Arizona Diamondbacks and Chicago White Sox meet Monday in MLB action at Rate Field. Here’s a White Sox vs Diamondbacks Prediction. This article will include a White Sox vs Diamondbacks Pick.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 39-38 on the year and play the Marlins, Giants, and Royals next. The Arizona Diamondbacks are batting .255 on the season, have a .332 OBP, and a .448 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.81 ERA and a 1.35 WHIP. Josh Naylor leads the Arizona Diamondbacks with 86 hits and 49 RBI, while Corbin Carroll and Lourdes Gurriel Jr. have combined for 144 hits and 84 RBI.

Eduardo Rodriguez gets the ball for the Arizona Diamondbacks, and he is 2-4 with a 5.93 ERA and 64 strikeouts this season. Rodriguez is 4-0 with a 3.36 ERA and 59 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 25-53 on the year and play the Giants, Dodgers, and Rockies next. The Chicago White Sox are batting .221 on the season, have a .293 OBP, and a .343 slugging percentage. The Chicago White Sox pitching staff has a 4.21 ERA and a 1.41 WHIP. Miguel Vargas leads the Chicago White Sox with 67 hits and 34 RBI while Lenyn Sosa and Chase Meidroth have combined for 114 hits and 26 RBI.

Shane Smith gets the ball for the Chicago White Sox, and he is 3-4 with a 2.85 ERA and 66 strikeouts this season. This will be Smith’s first career game against the Arizona Diamondbacks.

Why the Chicago White Sox will win

• The Diamondbacks have lost five of their last six games as favorites against American League opponents following a road loss.
• The White Sox have won three of their last four games as home underdogs after playing the previous day.
• The Diamondbacks have failed to cover the run line in each of their last seven games as road favorites following a loss.
• The White Sox have covered the run line in five of their last six home games after playing the previous day.
• The Diamondbacks have lost the first inning in four of their last five night games.
• The Diamondbacks have trailed after 3 innings in three of their last four games against American League opponents.
• The Diamondbacks have trailed after 5 innings in four of their last five road games against American League opponents that held a losing record.

Why the Arizona Diamondbacks will win

• The White Sox have lost each of their last 13 night games against National League opponents that held a winning record.
• The Diamondbacks have won seven of their last eight games at Rate Field.
• The Diamondbacks have covered the run line in seven of their last eight games at Rate Field.
• The White Sox have failed to cover the run line in seven of their last eight night games against National League opponents that held a winning record.
• The White Sox have trailed after 3 innings in seven of their last eight night games against National League opponents that held a winning record.
• The Diamondbacks have led after 5 innings in eight of their last nine night games against American League opponents that held a losing record.
• The Diamondbacks have won the first inning in three of their last four games against American League opponents that held a losing record.

Chicago White Sox Player Prop Facts

• Miguel Vargas has recorded a Double in three of his last four appearances in night games against NL teams that held a winning record.
• Andrew Benintendi has scored a run in each of his last five home appearances against NL opponents.
• Josh Rojas has hit a home run in two of his three previous home appearances against the Diamondbacks.
• Korey Lee has recorded at least one hit in each of his last six appearances against NL opponents that held a winning record.
• Luis Robert ranks 4th in the league in Steals (22) this season.

Arizona Diamondbacks Player Prop Facts

• Ketel Marte has hit a home run in six of the Diamondbacks’ last seven games against AL Central opponents.
• Eugenio Suarez has recorded a Double in each of the Diamondbacks’ last four road games against AL Central opponents.
• Eduardo Rodriguez has recorded a win in each of his last six appearances against AL Central opponents.
• Ketel Marte has recorded at least one RBI in each of the Diamondbacks’ last four games as favorites against AL Central opponents.
• Eduardo Rodriguez has recorded seven or more strikeouts in each of his last four appearances in night games against AL Central teams that held a losing record.
• Corbin Carroll has scored at least one run in each of the Diamondbacks’ last 12 games as favorites against AL Central opponents.
• Corbin Carroll has recorded at least one hit in each of the Diamondbacks’ last 12 games as favorites against AL opponents.
• Eugenio Suarez ranks 4th in the league in Home Runs (25) this season.

White Sox vs Diamondbacks Prediction

I’ve faded the White Sox a ton over the years, and I’m not thrilled to back them even in spots like this. However, Smith has been a bright spot for the White Sox, as he has a 2.85 ERA and 1.22 WHIP. Rodriguez has fallen off like Big Mac toppings, posting a 5.93 ERA and 1.62 WHIP, and in 33.1 road innings, he has a 6.21 ERA and .319 allowed batting average. Rodriguez is allowing a .303 allowed batting average on the season. This is a game the White Sox can win at home. I’ll gladly take the plus money here.