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White Sox vs Diamondbacks Prediction 6/24/25 MLB Picks Today

Arizona Diamondbacks (40-38) vs. Chicago White Sox (25-54)
June 24, 2025 7:40 pm EDT
The Line: Chicago White Sox 123 / Arizona Diamondbacks -150; Over/Under: 9
(Get latest betting odds)

The Arizona Diamondbacks and Chicago White Sox meet Tuesday in MLB action at Rate Field. Here’s a White Sox vs Diamondbacks Prediction. This article will include a White Sox vs Diamondbacks Pick.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 40-38 on the year and play the Marlins, Giants, and Royals next. The Arizona Diamondbacks are batting .256 on the season, have a .333 OBP, and a .451 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.74 ERA and a 1.34 WHIP. Josh Naylor leads the Arizona Diamondbacks with 87 hits and 51 RBI, while Geraldo Perdomo and Corbin Carroll have combined for 146 hits and 96 RBI.

Ryne Nelson gets the ball for the Arizona Diamondbacks, and he is 4-2 with a 3.88 ERA and 45 strikeouts this season. Nelson is 2-0 with a 0.84 ERA and 12 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 25-54 on the year and play the Giants, Dodgers, and Rockies next. The Chicago White Sox are batting .220 on the season, have a .293 OBP, and a .341 slugging percentage. The Chicago White Sox pitching staff has a 4.26 ERA and a 1.41 WHIP. Miguel Vargas leads the Chicago White Sox with 67 hits and 34 RBI while Lenyn Sosa and Chase Meidroth have combined for 115 hits and 26 RBI.

Jordan Leasure gets the ball for the Chicago White Sox, and he is 2-4 with a 4.23 ERA and 34 strikeouts this season. This will be Leasure’s first career game against the Arizona Diamondbacks.

Why the Chicago White Sox will win

  • The White Sox have won each of their last five night games following a home loss.
  • The Diamondbacks have lost four of their last six games as road favorites following a win.
  • The White Sox have covered the run line in 11 of their last 12 games following a home loss.
  • The Diamondbacks have failed to cover the run line in five of their last six road games against American League opponents that held a losing record.
  • The Diamondbacks have trailed after 5 innings in three of their last four games as road favorites against American League opponents.

Why the Arizona Diamondbacks will win

  • The White Sox have lost each of their last 14 night games against National League opponents that held a winning record.
  • The Diamondbacks have won each of their last six games against AL Central opponents.
  • The Diamondbacks have covered the run line in each of their last nine Tuesday games against American League opponents.
  • The White Sox have failed to cover the run line in eight of their last nine night games against National League opponents that held a winning record.
  • The Diamondbacks have won the first inning in four of their last five games against American League opponents that held a losing record.
  • The White Sox have trailed after 3 innings in eight of their last nine night games against National League opponents that held a winning record.
  • The Diamondbacks have led after 5 innings in each of their last six games against American League opponents that held a losing record.

Chicago White Sox Player Prop Facts

  • Josh Rojas has hit a home run in two of his three previous home appearances against the Diamondbacks.
  • Andrew Benintendi has scored a run in each of his last five home appearances against NL opponents.
  • Korey Lee has recorded at least one hit in each of his last six appearances against NL opponents that held a winning record.
  • Luis Robert ranks T4th in the league in Steals (22) this season.

Arizona Diamondbacks Player Prop Facts

  • Ketel Marte has hit a home run in seven of the Diamondbacks’ last eight games against AL Central opponents.
  • Ryne Nelson has recorded a win in each of his last three appearances with the Diamondbacks as favorites against AL Central opponents.
  • Ketel Marte has recorded at least one RBI in seven of the Diamondbacks’ last eight games against AL Central opponents.
  • Ryne Nelson has recorded five or more strikeouts in five of his last six appearances with the Diamondbacks as favorites against AL opponents.
  • Corbin Carroll has scored at least one run in each of his last 12 appearances with the Diamondbacks as favorites against AL Central opponents.
  • Eugenio Suarez has recorded a Double in four of the Diamondbacks’ last five road games against AL Central opponents.
  • Josh Naylor has recorded at least one hit in each of his last 12 appearances.

White Sox vs Diamondbacks Prediction

I’ve given the White Sox a chance here and there this season, and they’ve let me down every time. I’m back to blindly fading the White Sox, just a joke of a franchise. Nelson has been solid this season with a 3.88 ERA and 1.08 WHIP, and he’s allowed one or fewer runs in six of his last eight games. The Diamondbacks are in the thick of the wild card race and need to take advantage of games like this to keep pace. The White Sox are awful. The price is more than reasonable. Give me the Diamondbacks.

Randy Chambers's Free Pick: Arizona Diamondbacks -150

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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