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White Sox vs Mets Prediction 5/28/25 MLB Picks Today

White Sox vs Mets
May 28, 2025 1:10 pm EDT
The Line: White Sox +210 / Mets -260 / Over/Under: 7.5
(Get latest betting odds)

The Chicago White Sox are visiting the New York Mets on Wednesday, May 28th at the Citi Field in the third game of this series, with the Mets having a 2-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a White Sox vs Mets Prediction. We will examine:

The New York Mets’ recent form and player performance

The Chicago White Sox’s recent form and player performance

Recent betting trends and streaks involving the New York Mets

Recent betting trends and streaks involving the Chicago White Sox

Recent betting trends in games played between the Chicago White Sox vs New York Mets

A summary that ties it all together and produces a favorable betting outcome for the Chicago White Sox vs New York Mets game

New York Mets Preview

The New York Mets have a 34-21 record this season and are sitting in second place in the NL East. The Mets have a 21-6 home record and are 19-33 in over/under. They are coming off a 6-4 home victory over the White Sox, and are 5-1 in their last 6 games. Under is 9-3 in their last 12 games, and are playing the Rockies and the Dodgers next.

The Mets have a .247 batting average this season, a .329 OBP, and a .406 slugging percentage. New York’s pitching staff has a 2.80 ERA and 1.25 WHIP.  Francisco Lindor leads the Mets with 60 hits, while Pete Alonso leads the team in RBI with 42, in batting average with .291, and in home runs with 11.

Griffin Canning (R) will take the mound for the Mets, and he has a 5-1 record, 2.88 ERA, and 1.32 WHIP. He has been better at home with a 2.66 ERA across five home starts, but he had 3 earned runs in just 2.2 innings pitched against the Dodgers in his last start. In his previous start against the White Sox last season, he had a shutout performance in 6 innings pitched. Griffin Canning has a 3-0 record with an ERA of 1.89 and 23 strikeouts in 3 appearances against the White Sox in his career.

Chicago White Sox Preview

The Chicago White Sox have a 17-38 record this season and are sitting in last place in the AL Central. The White Sox have a 5-23 road record and are 25-26 in over/under. They are coming off a 4-6 road defeat by the Mets and have three consecutive losses. Over is 3-1 in their last 4 games, and they are playing the Orioles and the Tigers next.

The White Sox have a .220 batting average this season, a .292 OBP, and a .341 Slugging percentage. Chicago’s pitching staff has a 4.11 ERA and 1.38 WHIP. Lenyn Sosa leads the White Sox with 49 hits and a team-high .271 batting average. Miguel Vargas leads the team in RBI, with 26, and in home runs, with 8.

Shane Smith (R) will take the mound for the White Sox, and he has a 1-3 record, 2.36 ERA, and 1.11 WHIP. He has been better on the road with a 2.11 ERA across five road starts, and his previous road start was a quality start with just one earned run in 5 innings pitched. This will be his first career start against the Mets.

Why the New York Mets will win

  • The White Sox have lost each of their last 12 night games against National League opponents that held a winning record.
  • The Mets have won each of their last nine home games against American League opponents.
  • The Mets have covered the run line in seven of their last eight night games against AL Central opponents.
  • The White Sox have failed to cover the run line in each of their last six road games against National League opponents following a road loss.
  • The Mets have won the first inning in three of their last four night games against AL Central opponents.
  • The Mets have led after 5 innings in eight of their last nine night games against the White Sox.
  • The Mets have led after 3 innings in seven of their last eight night games against the White Sox.

Why the Chicago White Sox will win

  • The Mets have lost four of their last five Wednesday games as favorites against AL Central opponents.
  • The Mets have failed to cover the run line in eight of their last nine games against teams that held a losing record.
  • The White Sox have covered the run line in six of their last seven games.
  • The Mets have trailed after 5 innings in five of their last six games against American League opponents that held a losing record.

Total Runs Facts

  • Six of the Mets’ last seven games as favorites against the White Sox have gone UNDER the total runs line.
  • Five of the White Sox’s last six night games as underdogs have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last five night games against NL East opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mets’ last seven Wednesday games.

Matchup/League Facts

  • The Mets rank 1st in the league for ERA this season (2.80).
  • The Mets rank 1st in the league for home runs allowed this season (35).
  • The White Sox rank 30th in the league for hits this season (393).
  • The White Sox rank T29th in the league for triples this season (2).

White Sox vs Mets Prediction

The Mets are 10-1 in their last 11 meetings against the White Sox, and are 4-1 in their last 5 meetings in New York. Under is 10-2 in their last 12 meetings.

In this White Sox vs Mets Prediction, the Mets are coming as huge -260 home favorites. The Mets are rightfully favored, as they have a better overall record this season, and have been one of the best home teams in the league, while on the other hand, the White Sox have been one of the weakest road teams. The Mets also have the third-best bullpen ERA, and both starting pitchers are looking sharp with a combined 5.22 ERA. The White Sox have the second-worst batting average in the MLB, so I expect a low-scoring game. Take the under 7.5 runs.

Nikos Lagouretos's Free Pick: Under 7.5

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