White Sox vs Red Sox Prediction 4/19/25 MLB Picks Today

The Chicago White Sox are visiting the Boston Red Sox on Saturday, April 19^th at the Fenway Park in the second game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a White Sox vs Red Sox Prediction. We will examine:

The Boston Red Sox recent form and player performance

The Chicago White Sox recent form and player performance

Recent betting trends and streaks involving the Boston Red Sox

Recent betting trends and streaks involving the Chicago White Sox

Recent betting trends in games played between the Chicago White Sox vs Boston Red Sox

A summary that ties it all together and produces a favorable betting outcome for Chicago White Sox vs Boston Red Sox game

Boston Red Sox Preview

The Boston Red Sox have a 11-10 record this season and are sitting on the third place of the AL East. The Red Sox have a 5-3 home record and are 8-12 in over/under. They are coming off a 10-3 home victory over the Chicago White Sox and are playing the Mariners and the Guardians next. They are 4-1 in their last 5 games and 3-1 to the over in their last 4. The Red Sox have a .250 batting average this season, .323 OBP and .400 slugging percentage. Boston’s pitching staff has a 4.06 ERA and 1.30 WHIP.  Trevor Story leads the Red Sox with 26 hits, 5 home runs and a team-high .321 batting average, while Alex Bergman leads the team in RBI, with 16.

Garrett Crochet (L) will take the mound for the Red Sox, and he has a 2-1 record, 1.38 ERA and 0.88 WHIP. He looks sharp this season, with just four earned runs in his four starts this season. This will be his first start against the White Sox in his career.

Chicago White Sox Preview

The Chicago White Sox have a 4-15 record this season and are sitting on the last place of the AL Central. The White Sox have a 0-7 road record and are 8-8 in over/under. They are coming off a 3-10 road defeat by the Boston Red Sox, and have five consecutive losses. Under is 6-3-2 in their last 11 games and are playing the Twins and the Athletics next. The White Sox have a .195 batting average this season, .266 OBP and .297 Slugging percentage. Chicago’s pitching staff has a 4.60 ERA and 1.34 WHIP. Lenyn Sosa leads the White Sox with 17 hits and a team-high .279 batting average. Brooks Baldwin leads the team in RBI, with 9.

Shane Smith (R) will take the mound for the White Sox, and he has a 0-1 record, 2.04 ERA and 0.91 WHIP. He has been looking good in his first season in the majors so far, and in his previous start against the Red Sox this season, he gave up 2 runs in 6 innings of work.

Why the Boston Red Sox will win

• The White Sox have lost each of their last seven road games.
• The Red Sox have won four of their last five games.
• The White Sox have failed to cover the run line in each of their last five games.
• The Red Sox have covered the run line in four of their last five games.
• The Red Sox have led after 3 innings in seven of their last eight games as home favorites against AL Central opponents.
• The Red Sox have led after 5 innings in each of their last six home games against AL Central opponents.
• The White Sox have lost the first inning in each of their last three road games against American League opponents.

Why the Chicago White Sox will win

• The Red Sox have lost each of their last six day games against the White Sox following a win.
• The White Sox have won each of their last five day games against the Red Sox following a road loss.
• The Red Sox have failed to cover the run line in each of their last five day games against the White Sox at Fenway Park following a home win.
• The White Sox have covered the run line in five of their last six games at Fenway Park following a road loss.

Total Runs Facts

• Each of the Red Sox’s last four home games after playing the previous day have gone UNDER the total runs line.
• Each of the White Sox’s last three day games against AL East opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last 12 day games between the White Sox and Red Sox.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the White Sox’s last 11 day games against AL East opponents.

Matchup/League Facts

• The Red Sox rank 30th in the league for strikeouts against this season (203).
• The Red Sox rank T2nd in the league for doubles this season (42).
• The White Sox rank 30th in the league for hits this season (118).
• The White Sox rank 30th in the league for batting average this season (.195).

White Sox vs Red Sox Prediction

Both teams are tied 2-2 wins this season, with the White Sox winning their previous series this season by 2-1 wins in Chicago. Over/under is 2-2 in their four meetings this season, The Red Sox are 5-3 in their last 8 meetings against the White Sox.

In this White Sox vs Red Sox Prediction, the Red Sox are coming as huge -320 home favorites. The Red Sox are rightfully favored, as they have been the better team this season, and are putting their ace on the mound for this matchup. I do not expect the White Sox to get to Crochet in this one, and I also think the Red Sox will not score 10 runs again. In Shane Smith’s previous start against them, the Red Sox won by 3-1, and I expect another low-scoring affair today. Take the under 8.5 runs.