White Sox vs Tigers Prediction 6/5/25 MLB Picks Today

The Detroit Tigers and Chicago White Sox meet Thursday in MLB action at Rate Field. Here’s a White Sox vs Tigers Prediction. This article will include a White Sox vs Tigers Pick.

Detroit Tigers Betting Preview

The Detroit Tigers are 41-22 on the year and play the Cubs, Orioles, and Reds next. The Detroit Tigers are batting .251 on the season, have a .323 OBP, and a .410 slugging percentage. The Detroit Tigers’ pitching staff has a 3.21 ERA and a 1.16 WHIP. Riley Greene leads the Detroit Tigers with 67 hits and 42 RBI, while Kerry Carpenter and Dillon Dingler have combined for 106 hits and 53 RBI.

Casey Mize gets the ball for the Detroit Tigers, and he is 6-1 with a 2.82 ERA and 45 strikeouts this season. Mize is 0-4 with a 5.34 ERA and 30 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 19-43 on the year and play the Royals, Astros, and Rangers next. The Chicago White Sox are batting .221 on the season, have a .294 OBP, and a .342 slugging percentage. The Chicago White Sox pitching staff has a 4.21 ERA and a 1.38 WHIP. Lenyn Sosa leads the Chicago White Sox with 55 hits and 17 RBI, while Miguel Vargas and Chase Meidroth have combined for 94 hits and 33 RBI.

Sean Burke gets the ball for the Chicago White Sox, and he is 3-6 with a 4.20 ERA and 45 strikeouts this season. This will be Burke’s second career game against the Detroit Tigers.

Why the Chicago White Sox will win

• The White Sox have won each of their last six games as home underdogs following a home loss.
• The Tigers have lost four of their last five games as favorites against American League opponents following a road win.
• The White Sox have covered the run line in each of their last seven games following a home loss.
• The Tigers have failed to cover the run line in six of their last seven games against American League opponents following a road win.
• The White Sox have led after 5 innings in each of their last three day games against opponents that held a winning record.
• The White Sox have led after 3 innings in each of their last three day games against the Tigers at Rate Field.

Why the Detroit Tigers will win

• The Tigers have won each of their last 11 Thursday day games against AL Central opponents that held a losing record.
• The White Sox have lost each of their last seven day games against the Tigers following a home loss.
• The Tigers have covered the run line each of their last six Thursday games against AL Central opponents that held a losing record.
• The White Sox have failed to cover the run line in five of their last six day games against AL Central opponents following a home loss.
• The Tigers have won the first inning in three of their last four road games against American League opponents that held a losing record.
• The Tigers have led after 3 innings in eight of their last nine road day games.
• The Tigers have led after 5 innings in each of their last six Thursday day games as road favorites.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit a home run in two of his last three appearances in day games against AL Central teams that held a winning record.
• Andrew Benintendi has recorded at least one RBI in five of his last six appearances in day games against teams that held a winning record.
• Andrew Benintendi has scored a run in five of his last six home appearances against opponents that held a winning record.
• Andrew Vaughn has recorded at least one hit in each of his last nine Thursday appearances against teams that held a winning record.
• Mike Tauchman has recorded at least one Double in three of the White Sox’s last four day games.
• Andrew Benintendi has recorded a Single in five of his last six appearances in day games against teams that held a winning record.
• Luis Robert ranks T2nd in the league in Steals (21) this season.

Detroit Tigers Player Prop Facts

• Spencer Torkelson has hit a home run in three of the Tigers’ last four day games against AL Central opponents that held a losing record.
• Colt Keith has recorded at least one RBI in each of his last six road appearances against the White Sox.
• Casey Mize has recorded a win in each of his last four appearances against opponents that held a losing record.
• Casey Mize has recorded five or more strikeouts in each of his four previous appearances at Rate Field.
• Colt Keith has recorded at least one hit in each of his last 10 appearances.
• Parker Meadows has recorded a Double in three of his last four appearances against AL Central opponents.
• Javier Baez has recorded a Single in each of his last five road appearances after playing the previous day.
• Wenceel Perez has scored a run in each of his last nine road appearances against AL opponents that held a losing record.
• Casey Mize ranks T6th in the league for Wins (6) this season.

White Sox vs Tigers Prediction

As I’ve said before countless times, the White Sox are a team I’ve faded over the years, and that doesn’t stop now. The White Sox have won two games since May 25 and can’t string together an offense during these losses. Even with Burke pitching well and allowing 10 earned runs in his last 33 innings, it’s hard to back the White Sox with confidence. The Tigers continue to rack up the wins, and Mize has been sharp with his 2.82 ERA and 1.14 WHIP. Only one spot to go here. Give me the Tigers and the RL for max betting value.