White Sox vs Twins Prediction 5/28/26 MLB Picks Today
Minnesota Twins (27-29) vs. Chicago White Sox (28-27)
May 28, 2026 2:10 pm EDT
The Line: Chicago White Sox -126 / Minnesota Twins 105; Over/Under: 7.5
(Get latest betting odds)
In this article we will formulate a White Sox vs Twins prediction for this MLB game on Thursday, May 28th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup.
Chicago White Sox Betting Preview
The Chicago White Sox are 28-27 this year after they won two of the first three games in this series by scores of 3-1, 3-5, and 15-2. In game three, Chicago trailed 1-0 early in the game, but they scored the next 14 runs to run away with the easy win. The White Sox recorded 18 hits in the game and they were led by Meidroth, who went 2-5 with one home run and four RBIs. Sandlin allowed one hit and one earned run over 6.0 innings for the win, while Eisert allowed one earned run in relief. Prior to this series, Chicago lost two out of three against the Giants and two out of three against the Mariners.
This season, Chicago has a 4.40 ERA with a 1.33 WHIP and a .239 opponent batting average, while they have scored 256 runs with a .236 batting average and a .325 on base percentage. Munetaka Murakami has led the White Sox with 20 home runs and 40 RBIs, while Colson Montgomery has added 13 home runs and 33 RBIs. The projected starting pitcher for Chicago is Davis Martin, who is 7-1 with a 2.04 ERA and a 1.02 WHIP over 61.2 innings pitched this year.
Minnesota Twins Betting Preview
The Minnesota Twins are 27-29 this season after they lost game three by a score of 15-2 last night. Minnesota jumped out to a 1-0 lead in the first inning, but they didn’t score again until the eighth in the ugly loss. The Twins recorded three hits in the game and they were led by Clemens, who went 1-3 with one home run and one RBI. Prielipp allowed eight hits and six earned runs over 4.1 innings for the loss, while Adams allowed five earned runs in relief. Prior to this series, Minnesota swept the Red Sox in three games and won two out of three against the Astros.
This season, Minnesota has a 4.33 ERA with a 1.33 WHIP and a .245 opponent batting average, while they have scored 256 runs with a .236 batting average and a .319 on base percentage. Byron Buxton has led the Twins with 17 home runs and 27 RBIs, while Josh Bell has added five home runs and 29 RBIs. The projected starting pitcher for Minnesota is Kendry Rojas, who is 1-0 with a 1.26 ERA and a 1.47 WHIP over 14.1 innings pitched this season.
Why the Chicago White Sox will win
- The White Sox have won each of their last seven day games against American League opponents following a home win.
- The Twins have lost four of their last five games at Rate Field.
- The White Sox have covered the run line in each of their last 10 day games against American League opponents following a win.
- The Twins have failed to cover the run line in four of their last five games at Rate Field.
- The White Sox have led after 5 innings in seven of their last eight home games against AL Central opponents that held a losing record.
- The White Sox have led after 3 innings in each of their last four day games against the Twins.
Why the Minnesota Twins will win
- The White Sox have lost six of their last seven games as favorites following a win.
- The Twins have won five of their last six games as road underdogs.
- The White Sox have failed to cover the run line in each of their last seven games as favorites following a win.
- The Twins have covered the run line each of their last six games against teams that held a winning record.
- The Twins have led after 5 innings in each of their last four games at Rate Field against opponents that held a winning record.
Total Runs Facts
- Eight of the White Sox’s last nine home games have gone OVER the total runs line.
- Seven of the Twins’ last eight day games against AL Central opponents have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Twins’ last nine games as underdogs against American League opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last four games as home favorites against American League opponents.
Chicago White Sox Player Prop Facts
- Miguel Vargas has hit a home run in two of the White Sox’s last three games as home favorites.
- Austin Hays has recorded at least one hit in each of his last 10 Thursday day appearances with his team as a favorite.
Minnesota Twins Player Prop Facts
- Byron Buxton has hit at least one home run in three of his last four appearances at Rate Field against opponents that held a winning record.
- Ryan Jeffers has recorded at least one hit in each of his last nine appearances with the Twins as road underdogs against AL Central opponents.
White Sox vs Twins Prediction
Chicago bounced back from their game two loss with a blowout win on Thursday night and they will look for the series win here. The White Sox are 16-11 at home this year, while the Twins are 12-15 on the road. Minnesota has won three of their last five games, but they have scored two runs or fewer in two of their last three. The Twins are starting Rojas, who will only pitch a few innings, while Martin has allowed one earned run or fewer in four of his last five starts. Martin has been elite this year and I like the White Sox to win.