MLB Picks

Yankees vs Guardians Prediction 6/4/25 MLB Picks Today

Cleveland Guardians (32-27) vs. NY Yankees (37-22)
June 4, 2025 7:05 pm EDT
The Line: NY Yankees -185 / Cleveland Guardians 154; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Yankees vs Guardians prediction for this MLB game on Wednesday, June 4th at Yankee Stadium in New York. Let’s take a look at the prediction for this MLB matchup. 

New York Yankees Betting Preview

The New York Yankees are 37-22 this season after they won game one in this series by a score of 3-2 on Tuesday night. New York allowed Cleveland to tie the game at one in the seventh inning, but they scored twice in the bottom of the seventh for the win. The Yankees recorded five hits in the game, and they were led by Chisholm Jr, Volpe, and LeMahieu, who all had one RBI in the win. New York started Rodon, who allowed five hits and one earned run over 7.0 innings for the win, while Williams picked up the save. 

Prior to this series, the Yankees lost two out of three against the Dodgers, but did sweep the Angels in three games before that. New York has won seven of their last nine games, and they are currently first in the AL East standings. The New York pitching staff has a 3.58 ERA with a 1.18 WHIP and a .216 opponent batting average, while the offense has scored 322 runs with a .258 batting average and a .343 on-base percentage this season. Aaron Judge has led New York with 21 home runs and 50 RBIs, while Trent Grisham has added 13 home runs and 26 RBIs this year. The projected starting pitcher for New York is Clarke Schmidt, who is 2-2 with a 3.95 ERA and a 1.27 WHIP over 43.1 innings pitched this season. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 32-27 this year after they dropped game one in this series on Tuesday. Cleveland didn’t have much success at the plate in the game, but they scored once in the seventh and once in the ninth, before falling short in their comeback attempt. The Guardians recorded seven hits and they committed one error in the game, while they were led by Fry and Schneemann, who both had one RBI in the loss. Cleveland started Bibee, who allowed four hits and three earned runs over 6.1 innings for the loss, while Allard finished the final 1.2 innings out of the bullpen. 

Prior to this series, the Guardians won two out of three against the Angels, but lost two out of three against the Dodgers before that. Cleveland has won three of their last five games, and they are currently battling with Minnesota for second in the AL Central standings. The Cleveland pitching staff has a 4.05 ERA with a 1.38 WHIP and a .252 opponent batting average, while the offense has scored 237 runs with a .234 batting average and a .307 on-base percentage this season. Jose Ramirez has led Cleveland with 11 home runs and 29 RBIs, while Kyle Manzardo has added 10 home runs and 28 RBIs this year. The projected starting pitcher for Cleveland is Luis Ortiz, who is 2-6 with a 4.40 ERA and a 1.43 WHIP over 59.1 innings pitched this year. 

Why the Yankees will beat the Guardians

  • The Yankees have won each of their last eight games against American League opponents.
  • The Guardians have lost each of their last eight Wednesday night road games.
  • The Guardians have failed to cover the run line in each of their last eight Wednesday night road games.
  • The favorites have covered the run line in four of the Guardians’ last five games at Yankee Stadium.
  • The Yankees have led after 3 innings in seven of their last eight home games against American League opponents that held a winning record.
  • The Guardians have trailed after 5 innings in each of their last 12 Wednesday games against opponents that held a winning record.

Why the Guardians will beat the Yankees

  • The underdogs have won three of the Yankees’ last four games.
  • The underdogs have covered the run line in each of the Yankees’ last six games.
  • The Yankees have failed to cover the run line each of their last eight Wednesday night games against teams that held a winning record.

Total Runs Facts

  • Each of the Yankees’ last nine games as favorites against American League opponents have gone UNDER the total runs line.
  • Seven of the Guardians’ last eight night games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Yankees’ last 11 home games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last five games against American League opponents.

New York Yankees Player Prop Facts

  • Jazz Chisholm has scored a run in each of his last six home appearances after playing the previous day.
  • DJ LeMahieu has recorded at least one Single in each of his last 10 home appearances against the Guardians after playing the previous day.
  • DJ LeMahieu has recorded at least one hit in each of his last 11 home appearances against the Guardians after playing the previous day.
  • Giancarlo Stanton has hit a home run in five of his last six appearances against the Guardians.
  • Giancarlo Stanton has recorded at least one RBI in seven of his last eight appearances against AL opponents that held a winning record.

Cleveland Guardians Player Prop Facts

  • Carlos Santana has recorded a Double in three of his last four road appearances against AL opponents.
  • Jose Ramirez has hit a home run in two of the Guardians’ last three games against AL opponents.
  • Carlos Santana has recorded at least one RBI in four of his last five appearances at Yankee Stadium against AL opponents that held a winning record.
  • Jose Ramirez has scored at least one run in each of the Guardians’ last six night games against opponents that held a winning record.
  • Steven Kwan has recorded at least one Single in 12 of his last 13 road appearances against AL opponents that held a winning record.
  • Carlos Santana has recorded at least one hit in each of his last 12 appearances.

Yankees vs Guardians Prediction 

New York was able to get a low-scoring victory to start this series on Tuesday night, and they continue to hold a big lead in the AL East standings. The Yankees are 19-9 at home this year, while the Guardians are 15-16 on the road. Cleveland has scored four runs or more in three of their last five games, and they will face Schmidt, who has allowed two earned runs or fewer in three of his last five outings. New York has scored at least five runs in two of their last four games, and they will go against Ortiz, who has allowed two earned runs or fewer in three of his last four starts. Both of these pitchers have been solid in recent starts, and I think runs could be at a premium, so I like the under here. 

David Racey's Free Pick: Under 8.5

Need More? Get Premium Picks

David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

Related Articles

Back to top button