Yankees vs Guardians Prediction 6/5/25 MLB Picks Today

In this article, we will formulate a Yankees vs Guardians prediction for this MLB game on Thursday, June 5, at Yankee Stadium in Bronx, New York. Let’s take a look at the prediction for this MLB matchup.

Cleveland Guardians Betting Preview

The Cleveland Guardians (33-27, 16-16 Away) lost the series to the Dodgers, beat the Angels, and now are hoping to get a win in this rubber match against the Yankees. Following a 3-2 loss, the Guardians won Game 2, 4-0, last night. Angel Martinez led the offense with two RBI, while Luis Ortiz got the win after allowing no runs on three hits with seven strikeouts and three walks across 5.2 innings of work.

This year, the Guardians average 4.02 runs per game (21st in the MLB) on a .236/.308/.381 triple-slash. When it comes to pitching, the Guardians’ staff has a 3.98 ERA (19th) and 1.37 WHIP (23rd). Jose Ramirez leads the Guardians with a .327 batting average, 11 home runs, and 29 RBI this season.

The projected starting pitcher for the Guardians is Slade Cecconi, who is 1-1 in three starts this season, with a 5.28 ERA and 1.43 WHIP in 15.1 innings.

New York Yankees Betting Preview

The New York Yankees (37-23, 19-10 Home) swept the Angels, lost to the Dodgers, and now are trying to clinch the series against the Cleveland Guardians. The series is tied at 1-1 after last night’s 4-0 defeat, which was only the second time this season that the Yanks failed to score. Clarke Schmidt took the loss after allowing three runs on seven hits with eight strikeouts and one walk in 5.2 innings.

This season, the Yankees average 5.37 runs per game (3rd in the MLB) on a .257/.342/.463 triple-slash. When it comes to pitching, the Yankees’ staff has a 3.58 ERA (9th) and 1.19 WHIP (6th). Aaron Judge leads the Yankees with a .389 batting average, 21 home runs, and 50 RBI this season.

Max Fried will take the mound for the Yankees on Thursday. The 31-year-old left-hander has a 7-1 record in 12 starts this year with a 1.92 ERA and 0.97 WHIP in 75.0 innings.

Why the Yankees will cover

• The Guardians have lost each of their last 10 night games against the Yankees at Yankee Stadium following a win.
• The Yankees have won seven of their last eight home games against AL Central opponents following a loss.
• The Guardians have failed to cover the run line in seven of their last eight road games against AL East opponents following a road win.
• The Yankees have covered the run line in each of their last five night games against American League opponents following a loss.
• The Yankees have led after 5 innings in five of their last six games against American League opponents.

Total Runs Facts

• Each of the Yankees’ last 10 games against American League opponents have gone UNDER the total runs line.
• Six of the Guardians’ last seven road games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Yankees’ last 12 games at Yankee Stadium.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Guardians’ last five games.

Matchup/League Facts

• The Yankees rank 1st in the league for opponent batting average this season (.218).
• The Yankees rank 1st in the league for hits allowed this season (429).
• The Guardians rank T25th in the league for walks allowed this season (222).
• The Guardians rank 24th in the league for RBIs this season (228).

Yankees vs Guardians Prediction

The Yankees won six of the previous ten H2H encounters, but the Guardians lead this season’s series 3-2. I am backing the Yankees to tie that and win this game because of Max Fried. Fried is one of the biggest AL Cy Young Award candidates, and I am pretty sure he will bounce back from his worst display and first loss of the year against the Dodgers. Slade Cecconi, on the other hand, allowed 3+ runs in two of his three starts this season, and I am backing the Yanks to score 5+ off him in this one. Back the hosts to win and cover the run line.