Yankees vs Red Sox Prediction 8/21/25 MLB Picks Today

The Boston Red Sox and New York Yankees meet Thursday in MLB action at Yankee Stadium. Here’s a Yankees vs Red Sox Prediction. This article will include a Yankees vs Red Sox Pick.

Boston Red Sox Betting Preview

The Boston Red Sox are 68-59 on the year and play the Orioles, Pirates, and Guardians next. The Boston Red Sox are batting .252 on the season, have a .323 OBP, and a .425 slugging percentage. The Boston Red Sox pitching staff has a 3.75 ERA and a 1.30 WHIP. Jarren Duran leads the Boston Red Sox with 129 hits and 69 RBI, while Trevor Story and Ceddanne Rafaela have combined for 229 hits and 131 RBI.

Lucas Giolito gets the ball for the Boston Red Sox, and he is 8-2 with a 3.63 ERA and 87 strikeouts this season. Giolito is 3-2 with a 4.85 ERA and 34 strikeouts in his career against the New York Yankees.

New York Yankees Betting Preview

The New York Yankees are 69-57 on the year and play the Nationals, White Sox and Astros next. The New York Yankees are batting .251 on the season, have a .331 OBP, and a .454 slugging percentage. The New York Yankees pitching staff has a 4.00 ERA and a 1.25 WHIP. Aaron Judge leads the New York Yankees with 139 hits and 92 RBI while Cody Bellinger and Paul Goldschmidt have combined for 237 hits and 116 RBI.

Luis Gil gets the ball for the New York Yankees, and he is 1-1 with a 5.14 ERA and 14 strikeouts this season. Gil is 1-1 with a 1.10 ERA and 19 strikeouts in his career against the Boston Red Sox.

Why the New York Yankees will win

• The Yankees have won each of their last 10 Thursday home games.
• The Red Sox have lost each of their last nine Thursday night road games against AL East opponents.
• The Red Sox have failed to cover the run line in seven of their last eight night games against AL East opponents.
• The Yankees have covered the run line in each of their last four games.
• The Yankees have won the first inning in each of their last four night games.
• The Yankees have led after 3 innings in each of their last five games against American League opponents.
• The Red Sox have trailed after 5 innings in seven of their last eight night games against American League opponents that held a winning record.

Why the Boston Red Sox will win

• The Red Sox have won each of their last four games as underdogs against the Yankees.
• The Yankees have lost four of their last five games as home favorites against AL East opponents following a road win.
• The Red Sox have covered the run line in each of their last seven road games against the Yankees following a loss.
• The Yankees have failed to cover the run line in nine of their last 10 home games against AL East opponents following a road win.
• The Red Sox have won the first inning in each of their last three games as underdogs against AL East opponents.
• The Red Sox have led after 3 innings in four of their last five games against the Yankees.
• The Red Sox have led after 5 innings in four of their last five games against the Yankees.

New York Yankees Player Prop Facts

• Aaron Judge has hit a home run in each of his last five appearances at Yankee Stadium against AL East opponents that held a winning record.
• Paul Goldschmidt has recorded at least one Double in three of his last four appearances at Yankee Stadium against AL East opponents that held a winning record.
• Giancarlo Stanton has recorded at least one hit in each of his last 12 home appearances after playing the previous day.
• Jose Caballero ranks 1st in the league in Steals (40) this season.

Boston Red Sox Player Prop Facts

• Alex Bregman has hit a home run in four of his last five road appearances against AL opponents that held a winning record.
• Lucas Giolito has recorded six or more strikeouts in each of his five previous appearances against the Yankees.
• Jarren Duran has recorded at least one hit in each of the Red Sox’s last nine road games against AL East opponents.
• Lucas Giolito has recorded a win in each of his last six appearances against AL opponents that held a winning record.
• Trevor Story has recorded a Double in four of the Red Sox’s last five games as underdogs against AL opponents.

Yankees vs Red Sox Prediction

The Red Sox are putting together a rough week while the Yankees have found their form so it’s question who the favorite is in this spot. However, Gil has just 14 innings under his belt this season, and he hasn’t been good, allowing 15 hits and eight runs. Giolito has been solid this season, and he’s been even better this month where he’s allowed 15 hits and six runs in 19 innings. In 57 road innings, Giolito has a 3.47 ERA and .211 allowed batting average. I’ll take a shot with the Red Sox and the plus money.