Yankees vs Reds Prediction 6/21/26 MLB Picks Today
Cincinnati Reds (36-39) vs. NY Yankees (46-29)
June 21, 2026 1:35 pm EDT
The Line: NY Yankees -126 / Cincinnati Reds 104; Over/Under: 8.5
(Get latest betting odds)
In this article we will formulate a Yankees vs Reds prediction for this MLB game on Sunday, June 21st at Yankee Stadium in Bronx, New York. Let’s take a look at the prediction for this MLB matchup.
New York Yankees Betting Preview
The New York Yankees are 46-29 this season after they split the first two games in this series by scores of 5-0 and 2-10. In game two, New York led 1-0 in the first inning, but they allowed the next 10 runs for the ugly loss. The Yankees recorded eight hits and they committed one error in the game, while they were led by Goldschmidt, who went 1-5 with one home run and one RBI. Warren allowed eight hits and two earned runs over 5.2 innings for the loss, while Yarbrough allowed four earned runs in relief. Prior to this series, New York won two out of three against the White Sox and two out of three against the Blue Jays.
This season, New York has a 3.34 ERA with a 1.18 WHIP and a .225 opponent batting average, while they have scored 388 runs with a .246 batting average and a .332 on base percentage. Ben Rice has led the Yankees with 21 home runs and 52 RBIs, while Cody Bellinger has added 11 home runs and 49 RBIs. The projected starting pitcher for New York is Elmer Rodriguez, who is 0-1 with a 4.15 ERA and a 1.85 WHIP over 13.0 innings pitched this season.
Cincinnati Reds Betting Preview
The Cincinnati Reds are 36-39 this year after they won game two by a score of 10-2 on Saturday. Cincinnati took the lead in the third inning and never looked back in the blowout win. The Reds recorded 15 hits and they committed three errors, while they were led by Stewart, who went 2-4 with six RBIs in the game. Abbott allowed five hits and one earned run over 5.0 innings for the win, while Burke allowed one earned run in relief. Prior to this series, Cincinnati won two out of three against the Mets, but lost two out of three against the Diamondbacks before that.
This season, Cincinnati has a 4.63 ERA with a 1.47 WHIP and a .251 opponent batting average, while they have scored 321 runs with a .229 batting average and a .312 on base percentage. Sal Stewart has led the Reds with 14 home runs and 53 RBIs, while Elly De La Cruz has added 12 home runs and 37 RBIs. The projected starting pitcher for Cincinnati is Chase Burns, who is 8-1 with a 2.01 ERA and a 1.02 WHIP over 80.2 innings pitched this year.
Why the New York Yankees will win
- The Yankees have won seven of their last eight home games against National League opponents that held a losing record.
- The Reds have lost six of their last seven games following a win.
- The Yankees have covered the run line in seven of their last eight home games against National League opponents that held a losing record.
- The Reds have failed to cover the run line each of their last seven Sunday games against AL East opponents that held a winning record.
- The Yankees have led after 5 innings in six of their last seven home games against National League opponents that held a losing record.
- The Yankees have won the first inning in four of their last five home games against NL Central opponents that held a losing record.
- The Yankees have led after 3 innings in seven of their last eight home games against National League opponents that held a losing record.
Why the Cincinnati Reds will win
- The Reds have won five of their last six games as road underdogs against the Yankees.
- The Yankees have lost three of their last four games as favorites against NL Central opponents.
- The Reds have covered the run line in seven of their last eight road games against the Yankees.
- The Yankees have failed to cover the run line in 10 of their last 12 home games after playing the previous day.
- The Reds have led after 5 innings in six of their last seven games at Yankee Stadium.
- The Reds have led after 3 innings in each of their last four day games against the Yankees.
Total Runs Facts
- Seven of the Reds’ last eight games as underdogs against American League opponents have gone OVER the total runs line.
- Five of the Yankees’ last six home games against National League opponents have gone OVER the total runs line.
- There has been at least one run scored in the first inning in each of Gerrit Cole’s last four home appearances as a starter against the Reds.
- There has been no run scored during the first inning in five of the Reds’ last six games at Yankee Stadium.
New York Yankees Player Prop Facts
- Jazz Chisholm has hit at least one home run in four of his last five home appearances against NL Central opponents that held a losing record.
- Paul Goldschmidt has recorded at least one hit in each of the Yankees’ last eight day games.
Cincinnati Reds Player Prop Facts
- Spencer Steer has hit a home run in two of the Reds’ last three road games.
- Elly De La Cruz has recorded at least one hit in 21 of his last 22 road appearances against AL opponents that held a winning record.
Yankees vs Reds Prediction
New York comes into this matchup after losing two of their last three games and they have allowed 5+ runs in three of their last four. The Yankees are 22-14 at home this year, while the Reds are 17-20 on the road. Cincinnati has also lost two of their last three games and they have scored 5+ runs in three of their last five. The Reds are starting Burns, who has allowed two earned runs or fewer in five straight outings, while Rodriguez has allowed six earned runs in 13.0 innings this year. Take the Reds on the road in this one.