MLB Picks

Yankees vs Tigers Prediction 9/10/25 MLB Picks Today

Detroit Tigers (83-62) vs. NY Yankees (80-64)
September 10, 2025 7:05 pm EDT
The Line: NY Yankees -172 / Detroit Tigers 140; Over/Under: 8
(Get latest betting odds)

The Detroit Tigers and New York Yankees meet on Wednesday in MLB action from Yankee Stadium. Here’s a Yankees vs Tigers prediction. We will look at this from a betting perspective and determine the best Yankees vs Tigers pick.

What an Offensive Show for the Tigers

It was quite an offensive show for the Tigers on Tuesday, at least late in the game. The Tigers scored nine runs in the 7th inning, and that was the difference as they were able to secure the win. Parker Meadows hit a long bomb, and drove in three RBIs. Otherwise, it was mostly a balanced attack with eight different players driving in at least one run. Casey Mize got the star,t and he went six innings, giving up four hits and two runs. 

The Tigers are averaging 4.88 runs while their pitching is giving up 4.21 runs per game. The offense is ranked 8th while the pitching is ranked 12th. The offense has been quite impressive for this team, and they are going to probably need a couple of good innings to get the job done again. Getting the start for the Tigers will be Jack Flaherty who sits with a 7-13 record and an ERA of 4.85. Against the White Sox in his last start he went 4.1 innings giving up six hits and four runs. 

Why the Tigers Will Beat the Yankees

  • The Tigers have won four of their last five games as road underdogs.
  • The Yankees have lost three of their last four night games against American League opponents.
  • The Tigers have covered the run line in each of their last four games as underdogs against the Yankees.
  • The Yankees have failed to cover the run line in 11 of their last 12 Wednesday night games at Yankee Stadium.

Embarrassing for the Yankees

The bullpen was sure disappointing on Tuesday, and that ended up being the difference as they were knocked off. Heading into the 7th inning, the game was tied 2-2, ad somehow they still gave up 12 runs total. Fernando Cruz didn’t even record an out, and he gave up two hits and five earned runs. Mark Leiter Jr was also awful and he also didn’t record an out and giving up two hits and four runs. The only two runs scored by the Yankees were by home runs off the bats of Aaron Judge and Cody Bellinger. 

The Yankees are averaging 5.22 runs while their pitching is giving up 4.51 runs per game. The offense is ranked 1st while the pitching is ranked 14th. The bullpen is also now tired heading into this game after they used up most of it on Tuesday. Getting the start for the Yankees will be Carlos Rodon, who sits with a 16-7 record and an ERA Of 3.12. Against the Houston Astros in his last start he went six innings, giving up three hits and two runs. He gave up a home run and two walks. 

Why the Yankees Will Win

  • The Tigers have lost each of their last nine night games against the Yankees at Yankee Stadium following a win.
  • The Yankees have won each of their last seven night games against AL Central opponents following a home loss.
  • The Yankees have covered the run line in each of their last six night games against AL Central opponents following a loss.
  • The Tigers have failed to cover the run line in seven of their last eight night games at Yankee Stadium following a win.
  • The Tigers have trailed after 3 innings in four of their last five games as road underdogs against AL East opponents.
  • The Tigers have lost the first inning in three of their last four games as road underdogs against AL East opponents.

Yankees vs Tigers Prediction 

I do have some concerns about the Yankees confidence heading into this game but don’t let that fool you, they are the play in this game. Rodon sits with an ERA of 3.12, and the Tigers bats are going to be ice cold here. Through six innings, the Tigers bats weren’t strong, and it will be much of the same here. Flaherty has been more inconsistent, and the Yankees bats are going to string together some hits and New York will end up on top here. Back the Yankees on the money line.

Shane Mickle's Free Pick: Yankees ML

Need More? Get Premium Picks

Shane Mickle

Sports is about all Shane knows in this life! He has a passion for sports and writing, which makes working for Sportschatplace a perfect job for him! If you find him cheering for a team it's usually a Minnesota team, or the Kansas Jayhawks!

Related Articles

Back to top button