Celtics vs Cavaliers Prediction 10/29/25 NBA Picks Today
Cleveland Cavaliers (3-1) vs. Boston Celtics (1-3)
October 29, 2025 7:00 pm EDT
The Line: Boston Celtics +4.5; Over/Under: 231.5
(Get latest betting odds)
The Cleveland Cavaliers and Boston Celtics meet Wednesday in NBA action at the TD Garden. Here’s a Celtics vs Cavaliers Prediction. This article will include a Celtics vs Cavaliers Pick.
Cleveland Cavaliers Betting Preview
The Cleveland Cavaliers beat the Pistons and Bucks, and they play the Raptors next. The Cavs have won their last 3 games.
The Cleveland Cavaliers are averaging 119 points on 47.6 percent shooting and allowing 112.8 points on 45.7 percent shooting. Donovan Mitchell is averaging 31.3 points and 4 assists, while Evan Mobley is averaging 18.3 points and 4.8 assists. Sam Merrill is the third double-digit scorer and De’Andre Hunter is grabbing 4.5 rebounds. The Cleveland Cavaliers are shooting 36.8 percent from beyond the arc and 74.8 percent from the free throw line. The Cleveland Cavaliers are allowing 37.5 percent shooting from deep and are grabbing 40 rebounds per game.
Boston Celtics Betting Preview
The Boston Celtics lost to the Pistons, beat the Pelicans, and they play the 76ers next. The Celtics have lost 3 of their first 4 games.
The Boston Celtics are averaging 111.5 points on 44.8 percent shooting and allowing 107.8 points on 39.9 percent shooting. Jaylen Brown is averaging 29.7 points and 5.3 rebounds, while Derrick White is averaging 18.3 points and 3.7 rebounds. Payton Pritchard is the third double-digit scorer and Anfernee Simons is grabbing 2 rebounds. The Boston Celtics are shooting 31.9 percent from beyond the arc and 78.8 percent from the free throw line. The Boston Celtics are allowing 32.7 percent shooting from deep and are grabbing 42.8 rebounds per game.
Why the Boston Celtics will win
- The Celtics have won four of their last five games as home underdogs.
- The Cavaliers have lost each of their last six Wednesday games at TD Garden.
- The underdogs have covered the spread in each of the Cavaliers’ last four games at TD Garden.
- The Cavaliers have failed to cover the spread in six of their last seven games following a road win.
Why the Cleveland Cavaliers will win
- The Cavaliers have won each of their last 14 night games against Eastern Conference opponents that held a losing record.
- The Celtics have lost each of their last four games against Eastern Conference opponents.
- The Celtics have failed to cover the spread in eight of their last nine games against Central Division opponents following a win.
- The Cavaliers have covered the spread in each of their last five road games against Atlantic Division opponents following a win.
Total Points Facts
- Each of the Celtics’ last six games as underdogs following a road win have gone UNDER the total points line.
- Eight of the Cavaliers’ last 10 road games against Atlantic Division opponents have gone OVER the total points line.
Celtics vs Cavaliers Injury Report
The Celtics will be without Jayson Tatum due to an Achilles injury.
The Cavs will be without Darius Garland and Max Strus. Sam Merrill is out with a hip issue.
Celtics vs Cavaliers Prediction
The Cavs are going to get the benefit of the doubt because they’ve played the better ball up to this point. The Celtics are still trying to find their footing after a lot of roster turnover. However, the Celtics looked good in their last effort, and they’re at home.
The Cavs are down three rotation players, so I’m not thrilled to lay chalk with them on the road. Also, the underdog has covered 7 of the last 10 games between the Celtics and Cavs. I don’t think the Celtics are as bad as they’ve looked, so it feels like oddsmakers are overreacting. Give me the points.



