Celtics vs Pistons Prediction 11/26/25 NBA Picks Today
Detroit Pistons (15-2) vs. Boston Celtics (9-8)
November 26, 2025 5:00 pm EDT
The Line: Boston Celtics +3.5; Over/Under: 229.5
(Get latest betting odds)
The Detroit Pistons and Boston Celtics meet Wednesday in NBA action at the TD Garden. Here’s a Celtics vs Pistons Prediction. This article will include a Celtics vs Pistons Pick.
Detroit Pistons Betting Preview
The Detroit Pistons beat the Pacers and Bucks, and they play the Magic next. The Pistons have won 13 straight games.
The Detroit Pistons are averaging 118.9 points on 48.1 percent shooting and allowing 112.1 points on 43.9 percent shooting. Cade Cunningham is averaging 27.3 points and 5.4 rebounds, while Jalen Duren is averaging 20.6 points and 1.8 assists. Tobias Harris is the third double-digit scorer and Ausar Thompson is grabbing 6.2 rebounds. The Detroit Pistons are shooting 34.6 percent from beyond the arc and 74.2 percent from the free-throw line. The Detroit Pistons are allowing 35.3 percent shooting from deep and are grabbing 46.9 rebounds per game.
Boston Celtics Betting Preview
The Boston Celtics beat the Magic, lost to the Nets, and they play the Timberwolves next. The Celtics have won 4 of their last 5 games.
The Boston Celtics are averaging 113.3 points on 45.2 percent shooting and allowing 108.8 points on 43.9 percent shooting. Jaylen Brown is averaging 27.4 points and 5.7 rebounds, while Payton Pritchard is averaging 16.5 points and 4.3 rebounds. Derrick White is the third double-digit scorer and Anfernee Simons is grabbing 2.3 rebounds. The Boston Celtics are shooting 34.6 percent from beyond the arc and 77.3 percent from the free throw line. The Boston Celtics are allowing 35.8 percent shooting from deep and are grabbing 44.9 rebounds per game.
Why the Boston Celtics will win
- The Celtics have won each of their last seven home games against the Pistons.
- The Pistons have lost 12 of their last 13 games against Celtics teams that held a winning record.
- The Celtics have covered the spread in each of their last four games as home underdogs against Eastern Conference opponents.
- The Pistons have failed to cover the spread in five of their last six road games following a road win.
Why the Detroit Pistons will win
- The Pistons have won each of their last 13 games.
- The Celtics have lost three of their last four games against Central Division opponents.
- The Pistons have covered the spread in 10 of their last 11 games as road favorites against Atlantic Division opponents.
- The Celtics have failed to cover the spread in seven of their last eight games following a home win.
Total Points Facts
- Each of the Pistons’ last seven Wednesday games at TD Garden have gone OVER the total points line.
- Each of the Celtics’ last four games as home underdogs following a home win have gone OVER the total points line.
Boston Celtics Player Facts
- Derrick White rank 4th amongst qualified players for steals + blocks per game (3.0) this season.
- Jaylen Brown ranks 6th amongst qualified players for points per 36 minutes (31.0) this season.
Detroit Pistons Player Facts
- Cade Cunningham ranks 2nd amongst qualified players for assists per game (9.6) this season.
- Jalen Duren ranks 1st in the Eastern Conference amongst qualified players for FG% (67.1%) this season.
Matchup/League Facts
- The Celtics rank 1st in the league for opponent steals per game this season (5.8).
- The Celtics rank 1st in the league for turnovers per game this season (11.3).
- The Pistons rank 1st in the league for opponent assists per game this season (23.2).
- The Pistons rank 1st in the league for Q2 win percentage this season (82.4%).
Celtics vs Pistons Injury Report
The Celtics will be without Jayson Tatum due to an Achilles injury. Neemias Queta is out with an ankle injury.
The Pistons will be without Marcus Sasser and Bobi Klintman.
Celtics vs Pistons Prediction
The Celtics and the points at home is always worth a look, but I’m not stepping in front of the Pistons. The Pistons have won 13 straight games, and they’re 12-5 ATS on the season. The Pistons have a cover percentage of 70.5 percent, which is the best in the NBA. If it’s not broken, don’t fix it. Until the Pistons lose or stop covering numbers, I’m not betting against them. It’s really that simple. I’ll lay the small number with the Pistons as the wins continue to rack up.

