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Celtics vs Trail Blazers Prediction 3/5/25 NBA Picks Today

Portland Trail Blazers (28-34) vs. Boston Celtics (43-18)
March 5, 2025 7:00 pm EDT
The Line: Boston Celtics -10.5; Over/Under: 225
(Get latest betting odds)

The Portland Trail Blazers and Boston Celtics meet Wednesday in NBA action at the TD Garden. Here’s a Celtics vs Trail Blazers Prediction. This article will include a Celtics vs Trail Blazers Pick.

Portland Trail Blazers Betting Preview

The Portland Trail Blazers beat the 76ers, lost to the Cavs, and they play the Thunder, Pistons, and Warriors next. The Trail Blazers are 15-6 since starting the season with a 13-28 record.



The Portland Trail Blazers are averaging 110.7 points on 45.4 percent shooting and allowing 114.2 points on 47 percent shooting. Anfernee Simons is averaging 19 points and 2.8 rebounds, while Shaedon Sharpe is averaging 17.5 points and 3.9 rebounds. Deni Avdija is the third double-digit scorer and Deandre Ayton is grabbing 10.2 rebounds. The Portland Trail Blazers are shooting 34.6 percent from beyond the arc and 76.9 percent from the free-throw line. The Portland Trail Blazers are allowing 35.9 percent shooting from deep and are grabbing 44 rebounds per game.

Boston Celtics Betting Preview

The Boston Celtics lost to the Cavs, beat the Nuggets, and play the 76ers, Lakers, and Jazz next. The Celtics have seen three of their last four losses come at home.

The Boston Celtics are averaging 116.8 points on 46.1 percent shooting and allowing 108.2 points on 45.2 percent shooting. Jayson Tatum is averaging 26.8 points and 8.8 rebounds, while Jaylen Brown is averaging 23.2 points and 6 rebounds. Kristaps Porzingis is the third double-digit scorer and Derrick White is grabbing 4.3 rebounds. The Boston Celtics are shooting 37 percent from beyond the arc and 79.6 percent from the free throw line. The Boston Celtics are allowing 34.6 percent shooting from deep and are grabbing 44.9 rebounds per game.

Why the Boston Celtics will win

  • The favorites have won each of the Trail Blazers’ last 10 games.
  • The Trail Blazers have lost 10 of their last 11 games against Atlantic Division opponents that held a winning record.
  • The Trail Blazers have failed to cover the spread in each of their last seven games as underdogs against Atlantic Division opponents following a win.
  • The favorites have covered the spread in eight of the Trail Blazers’ last 10 games.

Why the Portland Trail Blazers will win

  • The Trail Blazers have won each of their last 11 night games against Eastern Conference opponents.
  • The Celtics have lost four of their last five games as home favorites against Western Conference opponents following a win.
  • The Trail Blazers have covered the spread in each of their last 12 games against Eastern Conference opponents.
  • The Celtics have failed to cover the spread in 11 of their last 12 games as favorites following a home win.

Matchup/League Facts

  • The Celtics rank 1st in the league for opponent blocks per game this season (3.8).
  • The Celtics rank 1st in the league for three-point field goals made per game this season (17.8).
  • The Trail Blazers rank 29th in the league for opponent steals per game this season (9.5).
  • The Trail Blazers rank 29th in the league for Q1 points per game this season (26.1).

Celtics vs Trail Blazers Injury Report

Jrue Holiday and Kristaps Porzingis are doubtful for the Celtics, while Jaylen Brown and Jayson Tatum are questionable.

The Trail Blazers won’t have Robert Williams III, Deni Avdija, Deandre Ayton, and Matisse Thybulle. Jerami Grant is questionable for Portland.

Celtics vs Trail Blazers Prediction

Another Celtics game, another inflated line they probably won’t cover. The Celtics are 26-34-1 ATS on the season, and they’re 2-8 ATS in their last 10 games as a double-digit favorite. Since January 10, the Celtics have outright lost three times as a double-digit favorite. It doesn’t help that the Celtics are dealing with a bunch of injuries to key players as well. Oh, the Trail Blazers are also a good team all of a sudden, winning 15 of their last 21 games and improving to 36-25-1 ATS on the season. I’ll continue to fade the Celtics in these massive favorite spots, as they just don’t cash tickets.

Randy Chambers's Free Pick: Portland Trail Blazers +10.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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