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Knicks vs 76ers Prediction 5/6/26 NBA Picks Today

Philadelphia 76ers (45-37) vs. NY Knicks (53-29)
May 6, 2026 7:00 pm EDT
The Line: NY Knicks -6.5; Over/Under: 215.5
(Get latest betting odds)

The Philadelphia 76ers and NY Knicks meet Wednesday in NBA Game 2 at Madison Square Garden. Here’s a Knicks vs. 76ers Prediction. This article will include a Knicks vs. 76ers Pick.

Philadelphia 76ers Betting Preview

The Philadelphia 76ers need a win to even up the series at 1-1 before heading back home. The 76ers have won 11 of their last 19 games.

The Philadelphia 76ers are averaging 103 points on 44.2 percent shooting and allowing 110.4 points on 45.8 percent shooting. Joel Embiid is averaging 25.2 points and 5.8 assists, while Tyrese Maxey is averaging 25.1 points and 4.6 rebounds. Paul George is the third double-digit scorer, and VJ Edgecombe is grabbing 6.1 rebounds. The Philadelphia 76ers are shooting 35.4 percent from beyond the arc and 80.9 percent from the free-throw line. The Philadelphia 76ers are allowing 35.6 percent shooting from deep and are grabbing 39.5 rebounds per game.

NY Knicks Betting Preview

The NY Knicks look for another win to take a quick 2-0 series lead. The Knicks have won 17 of their last 23 games.

The NY Knicks are averaging 120.6 points on 51.8 percent shooting and allowing 100 points on 43.3 percent shooting. Jalen Brunson is averaging 27.6 points and 2.3 rebounds, while OG Anunoby is averaging 21 points and 1.1 assists. Karl-Anthony Towns is the third double-digit scorer, and Mikal Bridges is dishing out 2.1 assists. The NY Knicks are shooting 40.2 percent from beyond the arc and 76.8 percent from the free-throw line. The NY Knicks are allowing 31.9 percent shooting from deep and are grabbing 44.9 rebounds per game.

Why the New York Knicks will win

  • The Knicks have won each of their last 10 games against Atlantic Division opponents.
  • The 76ers have lost five of their last six playoff games at Madison Square Garden.
  • The Knicks have covered the spread in each of their last eight games against Atlantic Division opponents that held a winning record.
  • The 76ers have failed to cover the spread in each of their last three games against Knicks teams that held a winning record.

Why the Philadelphia 76ers will win

  • The 76ers have won each of their last seven road games against Atlantic Division opponents following a loss.
  • The Knicks have lost four of their last six playoff games as home favorites following a win.
  • The 76ers have covered the spread in each of their last seven road games against Atlantic Division opponents following a loss.
  • The Knicks have failed to cover the spread in four of their last five home games against 76ers teams that held a winning record.

Total Points: Facts

  • Seven of the Knicks’ last eight home games against the 76ers following a home win have gone UNDER the total points line.
  • Each of the 76ers’ last four games as underdogs following a road loss have gone UNDER the total points line.

New York Knicks Player Facts

  • Mitchell Robinson ranks 1st amongst qualified players for rebounds per 36 minutes (16.1) this season.
  • Karl-Anthony Towns ranks 2nd amongst qualified players for rebounds per game (11.9) this season.

Philadelphia 76ers Player Facts

  • Tyrese Maxey ranks 1st in the league for fast break points (382) this season.
  • Andre Drummond has recorded 11+ rebounds in three consecutive appearances—the equal-longest active streak of any player in the league.

Matchup/League Facts

  • The Knicks rank 1st in the league for opponent offensive rebounds per game this season (10.0).
  • The Knicks rank 1st in the league for Q4 opponent points per game this season (25.3).
  • The 76ers rank 29th in the league for assists per game this season (24.6).
  • The 76ers rank 29th in the league for Q3 points per game this season (27.3).

Knicks vs 76ers Injury Report

Joel Embiid is probable for the 76ers despite an ankle sprain. Tyrese Maxey is probable despite a finger issue.

The Knicks don’t have any players listed on their injury report.

Knicks vs 76ers Prediction

I’d like to think game 1 was just one game and the 76ers can make a series of this. However, the Knicks have smoked the boots of opponents in each of the last 4 games. The offense is humming and the defense has allowed fewer than 100 points in all of those games as well.

The Knicks have covered 8 of their last 10 games. Also, with less time off, it’s going to be tougher for Embiid, who is still working his way back into the mix. The winner in 9 of the last 10 games between the Knicks and 76ers has covered. I expect a more competitive game here but that’s not saying much. I’ll lay the points with the Knicks.

Randy Chambers's Free Pick: NY Knicks -6.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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