Broncos vs Jaguars Prediction 12/21/25 NFL Picks Today

The Jacksonville Jaguars and Denver Broncos meet Sunday in NFL action at Empower Field. Here’s a Broncos vs Jaguars Prediction. This article will include a Broncos vs Jaguars Pick.

Jacksonville Jaguars Betting Preview

The Jacksonville Jaguars beat the Colts and Jets, and they play the Colts next. The Jacksonville Jaguars have won 5 straight games. Trevor Lawrence is completing 59.7 percent of his passes for 3,210 yards, 23 touchdowns, and 11 interceptions. Parker Washington and Brian Thomas Jr. have combined for 1,101 receiving yards and 5 touchdowns, while Brenton Strange has 32 receptions.

The Jacksonville Jaguars ground game is averaging 120.7 yards per contest, and Travis Etienne Jr. leads the way with 949 yards and 7 touchdowns. Defensively, Jacksonville is allowing 20.9 points and 308.5 yards per game. Foyesade Oluokun leads the Jacksonville Jaguars with 111 tackles, Josh Hines-Allen has 7 sacks and Devin Lloyd has 5 interceptions.

Denver Broncos Betting Preview

The Denver Broncos beat the Raiders and Packers, and they play the Chiefs next. The Denver Broncos have won 11 straight games. Bo Nix is completing 63.5 percent of his passes for 3,256 yards, 23 touchdowns, and 9 interceptions. Troy Franklin and Courtland Sutton have combined for 1,512 receiving yards and 12 touchdowns, while Evan Engram has 41 receptions.

The Denver Broncos ground game is averaging 119.5 yards per contest, and J.K. Dobbins leads the way with 772 yards and 4 touchdowns. Defensively, Denver is allowing 18.6 points and 287.7 yards per game. Alex Singleton leads the Denver Broncos with 111 tackles, Nik Bonitto has 12.5 sacks and Dondrea Tillman has 2 interceptions.

Why the Denver Broncos will win

• The Broncos have won each of their last 12 home games.
• The Jaguars have lost each of their last eight road games without Travis Etienne.
• The Broncos have covered the spread in each of their last eight games as favorites without Alex Singleton.
• The Jaguars have failed to cover the spread in seven of their last eight games without Brenton Strange.
• The Broncos have won the first quarter in eight of their last 10 home games against teams that held a winning record.
• The Jaguars have lost the first half in 13 of their last 14 road games against AFC West opponents.
• The Broncos have scored the first touchdown in six of their last seven games as favorites against AFC opponents.

Why the Jacksonville Jaguars will win

• The Broncos have lost each of their last six Week 16 games against AFC opponents.
• The Jaguars have won each of their last three games as underdogs without Travon Walker.
• The Broncos have failed to cover the spread in each of their last eight Week 16 games against AFC opponents.
• The underdogs have covered the spread in each of the Broncos’ last six games.
• The Jaguars have scored the first touchdown in each of their last six games.
• The Jaguars have won the first quarter in four of their last five games as underdogs.
• The Jaguars have won the first half in each of their last five games against AFC opponents.

Total Points Facts

• Each of the Broncos’ last six games in December have gone OVER the total points line.
• Eight of the Jaguars’ last nine games as underdogs following a win have gone OVER the total points line.
• Three of the last four Sunday games at Empower Field at Mile High have gone OVER the total points line.

Denver Broncos Player Prop Facts

• Bo Nix has recorded 24+ completions in four of the Broncos’ last five home games against AFC opponents.
• Bo Nix has recorded 247+ passing yards in each of the Broncos’ last four Sunday home games.
• Jaleel McLaughlin has recorded 19+ rushing yards in each of his last eight appearances with the Broncos as home favorites.
• Jaleel McLaughlin has recorded 34+ rushing and receiving yards in each of the Broncos’ last four December games as home favorites.
• Courtland Sutton has recorded 59+ receiving yards in each of the Broncos’ last six Sunday home games.
• Marvin Mims Jr. has scored at least one touchdown in each of the Broncos’ last four games as favorites against teams that held a winning record.
• Heading into Week 16, Bo Nix ranks 1st amongst qualified players for sack percentage (3.1%) this season.

Jacksonville Jaguars Player Prop Facts

• Travis Etienne has scored two or more touchdowns in three of the Jaguars’ last four games against AFC opponents.
• Trevor Lawrence has recorded 20+ completions in each of his five previous December road appearances against AFC opponents.
• Trevor Lawrence has recorded 229+ passing yards in eight of his last nine December appearances against AFC opponents.
• Travis Etienne has scored at least one touchdown in five of the Jaguars’ last six games.
• Brian Thomas has recorded 47+ receiving yards in each of his 12 previous appearances with the Jaguars as underdogs against AFC opponents.
• Trevor Lawrence has recorded 16+ rushing yards in seven of the Jaguars’ last eight games.
• Jakobi Meyers has recorded 64+ rushing and receiving yards in eight of his last nine appearances against AFC West opponents.
• Heading into Week 16, Trevor Lawrence has recorded the equal-most passing touchdowns in a single game this season (5 vs Jets, Week 15).

Matchup/League Facts

• Heading into Week 16, the Broncos rank 1st in the NFL in sacks (58.0) this season.
• Heading into Week 16, the Broncos rank 1st in the NFL in red zone percentage against (38.5%) this season.
• Jaguars – seven different players have recorded 70+ receiving yards in a game this season – equal-most in the NFL, heading into Week 16.
• Jaguars – five different players have recorded 90+ receiving yards in a game this season – equal-most in the NFL, heading into Week 16.

Broncos vs Jaguars Prediction

The Broncos are going to be favored at home behind their elite defense, and they haven’t lost since week 3. I get it. However, the Jaguars and the free points is where the values at. The Jaguars don’t get much love nationally, but they’ve won 5 straight games and are top-10 in both scoring offense and scoring defense. The Jaguars have outright won their last 2 games as an underdog.

Despite all of this winning, the Broncos are 6-7-1 ATS on the season, while the Jaguars are 9-4-1 ATS. Since October, the Broncos are 1-5 ATS as a favorite of at least 3 points. The gaurs have the best run defense in the league, which means Nix is going to be forced to make plays with his arm for Denver to win. I’m not a believer quite yet. Give me the Jaguars are the free field goal.