Broncos vs Rams Prediction 9/27/26 NFL Picks Today
LA Rams (1-1) vs. Denver Broncos (1-1)
September 27, 2026 8:20 pm EDT
The Line: Denver Broncos +2.5; Over/Under: 44.5
(Get latest betting odds)
In this article we will formulate a Broncos vs Rams prediction for this NFL game on Sunday, September 27th at Mile High Stadium in Denver, Colorado. Let’s take a look at the prediction for this week 3 matchup.
Denver Broncos Betting Preview
The Denver Broncos are 1-1 this season after they defeated the Jaguars by a score of 20-13 last week. Denver trailed 10-3 at halftime and 13-3 in the third quarter, but they scored the last 17 points to escape with the win. The Broncos out gained Jacksonville by a total of 392-268, went 4-11 on third downs, and tied the turnover battle at one in the game. Bo Nix threw for 288 yards, one touchdown, and one interception, while Jaylen Waddle caught eight passes for 138 yards. Jonah Coleman rushed 10 times for 39 yards and one score in the win.
Prior to that game, Denver lost to the Chiefs by a score of 31-10 in week one. The Broncos have scored 15.0 points per game with 201.5 passing yards and 82.5 rushing yards per game, while they have allowed 22.0 points against per game this season. Bo Nix has thrown for 419 yards with two touchdowns and two interceptions, while Jaylen Waddle has nine receptions for 140 yards this season.
Los Angeles Rams Betting Preview
The Los Angeles Rams are 1-1 this year after they defeated the Giants by a score of 28-6 on Monday night. Los Angeles led 14-3 at halftime and they cruised to the win in the second half, as New York lost their starting QB. The Rams out gained NY by a total of 481-182, went 5-9 on third downs, and lost the turnover battle by a total of 2-1 in the game. Matthew Stafford threw for 327 yards, four touchdowns, and one interception, while Davante Adams caught eight passes for 195 yards and two scores. Kyren Williams rushed 12 times for 85 yards in the game.
Prior to that win, Los Angeles lost to the 49ers by a score of 27-7 in week one in Australia. The Rams have scored 17.5 points per game with 243.0 passing yards and 142.5 rushing yards per game, while they have allowed 16.5 points against per game this season. Matthew Stafford has thrown for 482 yards with four touchdowns and two interceptions, while Davante Adams has 11 receptions for 221 yards and two scores this year.
Why the Denver Broncos will win
- The Broncos have won each of their last nine games against NFC opponents.
- The Rams have lost five of their last six road games in September.
- The Broncos have covered the spread in each of their last six home games without Alex Singleton.
- The Rams have failed to cover the spread in each of their last four road games.
- The Broncos have won the first quarter in three of their last four games as home underdogs following a home win.
- The Broncos have scored the first touchdown in each of their last four Sunday games as underdogs.
- The Rams have lost the first half in five of their last six games as slight favorites (<-3.5 points).
Why the Los Angeles Rams will win
- The Rams have won each of their last eight games against AFC opponents.
- The Broncos have lost three of their last four games without Jonathon Cooper.
- The Rams have covered the spread in each of their last eight games against AFC opponents.
- The Broncos have failed to cover the spread in each of their last four games without Nik Bonitto.
- The Rams have scored the first touchdown in eight of their last nine games as favorites following a win.
- The Broncos have lost the first half in each of their last seven games as home underdogs against NFC opponents.
- The Rams have won the first quarter in each of their last six road openers.
Total Points Facts
- Each of the Rams’ last six road games following a home win have gone OVER the total points line.
- Ten of the Broncos’ last 11 home games in September have gone UNDER the total points line.
- Each of the last three Sunday games at Empower Field at Mile High have gone UNDER the total points line.
Denver Broncos Player Prop Facts
- Courtland Sutton has recorded 66+ receiving yards in each of his last nine home appearances against NFC opponents.
- Bo Nix has recorded 242+ passing yards in each of the Broncos’ last seven games against NFC opponents.
- Bo Nix has recorded 22+ rushing yards in six of his seven previous appearances with the Broncos as underdogs following a home win.
- Jaylen Waddle has recorded 72+ rushing and receiving yards in six of his last seven appearances with his team as a home underdog.
- Troy Franklin has scored at least one touchdown in each of the Broncos’ last four home games against NFC opponents.
- Jarrett Stidham has recorded 17+ completions in each of his five previous appearances as a starter.
- Heading into Week 3, Alex Singleton has recorded the equal-most tackles in a single game this season (16 vs Chiefs, Week 1).
Los Angeles Rams Player Prop Facts
- Kyren Williams has recorded 54+ rushing yards in 18 of the Rams’ last 19 games as favorites following a win.
- Matthew Stafford has recorded 240+ passing yards in each of his 17 previous September appearances against AFC opponents.
- Kyren Williams has scored at least one touchdown in seven of the Rams’ last eight games as favorites following a win.
- Matthew Stafford has recorded 23+ completions in nine of the Rams’ last 10 games as favorites following a home win.
- Tyler Higbee has recorded 12+ receiving yards in each of his last nine Sunday appearances.
- Kyren Williams has recorded 72+ rushing and receiving yards in 15 of his last 16 appearances following a home win.
- Heading into Week 3, Matthew Stafford has recorded the equal-most passing touchdowns in a single game this season (4 vs Giants, Week 2).
Matchup/League Facts
- Broncos – one different rookies have recorded at least one touchdown this season – equal-most in the NFL, heading into Week 3.
- Heading into Week 3, the Broncos have lost the second quarter in each of their last two games – equal-longest active streak in the league.
- Rams – two different players have recorded 70+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
- Heading into Week 3, the Rams rank 32nd in the NFL in average kickoff return (21.1 yards) this season.
Broncos vs Rams Prediction
Denver comes into this matchup after waking up in the second half last week to get the win, but they really struggled in the first six quarters of the season. The Broncos need to find more consistency on offense, which starts with Nix. Los Angeles bounced back from their week one loss with a blowout win on Monday night, but that was mostly due to Dart getting hurt for New York. I am very interested to see how this game plays out, but with two strong defenses, I like the under here.
