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Broncos vs Titans Prediction 9/7/25 NFL Picks Today

Tennessee Titans (2-1) vs. Denver Broncos (3-0)
September 7, 2025 4:05 pm EDT
The Line: Denver Broncos -8.5; Over/Under: 42.5
(Get latest betting odds)

The Tennessee Titans and Denver Broncos meet Sunday in NFL action at Empower Field at Mile High. Here’s a Broncos vs Titans Prediction. This article will include a Broncos vs Titans Pick.

Tennessee Titans Betting Preview

The Tennessee Titans won 3 games last season and enter the second year under coach Brian Callahan. The Titans have missed the playoffs in each of the last three seasons.

The Titans will give the keys of the offense to rookie Cam Ward, who had an incredible year with the Miami Hurricanes and showed playmaking ability. The Titans have a number one receiver in Calvin Ridley, and there’s talent at running back with Tony Pollard and Tyjae Spears leading the charge. Tight end Chig Okonkwo could be a difference maker, and the addition of Kevin Zeitler should improve an offensive line that struggled at times last season.

The Titans have an above-average defensive line led by T’Vondre Sweat and Jeffery Simmons, which proved to be solid against the run. The questions are at linebacker and secondary. A full season of L’Jarius Sneed will help, while rookie Kevin Winston Jr. is a tone setter who could find himself in the starting lineup. The addition of Cody Barton will help the linebacker group.

You can’t have real expectations on a Titans team that was the worst in the league last year. However, maybe this franchise is heading in the right direction after a decent offseason.

Denver Broncos Betting Preview

The Denver Broncos won 10 games last year and enter the third year under coach Sean Payton. The Broncos haven’t won double-digit games in two straight seasons since the 2015 season.

Quarterback Bo Nix flashed as a rookie, and it will be interesting to see if he can avoid a sophomore slump. The Broncos return all five offensive linemen from last year and added tight end Evan Engram. The ground game could improve with RJ Harvey and JK Dobbins, while receivers Courtland Sutton and Marvin Mims Jr. are underrated. This offense isn’t flashy, but it can get the job done with hard-nosed play.

Defensively, the Broncos were the best in the league last season. That shouldn’t change much with Dre Greenlaw and Talanoa Hufanga joining the squad. Patrick Surtain II is fresh off winning Defensive Player of the Year, and rookie Sai’vion Jones should see a lot of snaps up front. This Broncos’ defense is elite and is the main reason they can give the Chiefs a run for their money in the AFC West. If Nix improves on a solid rookie season, the Broncos should be thinking deep playoff run.

Why the Denver Broncos will win

  • The favorites have won each of the Broncos’ last 14 games.
  • The Titans have lost 16 of their last 17 Sunday road games.
  • The Broncos have covered the spread in each of their last nine games as favorites.
  • The Titans have failed to cover the spread in 15 of their last 16 Sunday games.
  • The Broncos have scored the first touchdown in six of their last eight games as home favorites against AFC opponents.
  • The Titans have won the first quarter in three of their last four games as heavy underdogs (>+7.0 points).
  • The Broncos have won the first half in eight of their last nine games as home favorites.

Why the Tennessee Titans will win

  • The Titans have won each of their last three season openers as underdogs against AFC opponents.
  • The Broncos have lost three of their last four season openers as favorites.
  • The underdogs have covered the spread in seven of the Titans’ last eight Week 1 games.
  • The Broncos have failed to cover the spread in each of their last four September games as favorites.
  • The Titans have scored the first touchdown in seven of their last eight games as underdogs against AFC opponents.
  • The Titans have won the first quarter in seven of their last eight games as underdogs against AFC opponents.
  • The Titans have won the first half in each of their last seven season openers as underdogs.

Denver Broncos Player Prop Facts

  • J.K. Dobbins has scored at least one touchdown in four of his last five appearances with his team as a home favorite.
  • Courtland Sutton has recorded 70+ receiving yards in seven of the Broncos’ last eight Sunday games.
  • Bo Nix has recorded 215+ passing yards in nine of the Broncos’ last 10 regular season games.
  • J.K. Dobbins has recorded 50+ rushing yards in each of his last eight Sunday appearances with his team as a favorite.
  • Bo Nix has recorded 22+ completions in four of the Broncos’ last five Sunday regular season games.
  • Marvin Mims Jr. has recorded 42+ rushing and receiving yards in six of the Broncos’ last seven regular season games.
  • Patrick Surtain recorded the equal-most interceptions in a single game last season (2 vs Raiders, Week 5).

Tennessee Titans Player Prop Facts

  • Tony Pollard has recorded 70+ rushing yards in each of his last six September road appearances.
  • Tyler Lockett has recorded 28+ receiving yards in each of his last nine September appearances with his team as an underdog.
  • Tyjae Spears has scored at least one touchdown in three of his last four appearances with the Titans as underdogs against AFC opponents.
  • Calvin Ridley has recorded 59+ rushing and receiving yards in each of the Titans’ last eight games against AFC opponents.
  • Amani Hooker recorded the equal-most interceptions in a single game last season (2 vs Patriots, Week 9).

Broncos vs Titans Prediction

This is a lot of points to lay in a season opener, but I’m going to do it anyway. The Titans weren’t good last season, and it’s hard to make big leaps in one offseason. Also, as talented as Ward is, his first game is on the road in high altitude against the best defense in the league. Could there be a worst spot to get your feet wet?

This Broncos’ defense should be drooling about this matchup. I do question if the Broncos have the offensive horses to pull away, but they were also 4-0 ATS last season when favorites of 5 or more points. Give me the Broncos in a comfortable season opening win.

Randy Chambers's Free Pick: Denver Broncos -8.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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