Browns vs Packers Prediction 9/21/25 NFL Picks Today

The Green Bay Packers and Cleveland Browns meet Sunday in NFL action at Huntington Bank Field. Here’s a Browns vs Packers Prediction. This article will include a Browns vs Packers Pick.

Green Bay Packers Betting Preview

The Green Bay Packers beat the Lions and Commanders, and they play the Cowboys next. The Packers have won 11 of their last 15 regular season games. Jordan Love is completing 66 percent of his passes for 480 yards, 4 touchdowns, and 0 interceptions. Tucker Kraft and Romeo Doubs have combined for 236 receiving yards and 3 touchdowns, while Dontayvion Wicks has 6 receptions.

The Green Bay Packers ground game is averaging 106.5 yards per contest, and Josh Jacobs leads the way with 150 yards and 2 touchdowns. Defensively, Green Bay is allowing 15.5 points and 238 yards per game. Edgerrin Cooper leads the Green Bay Packers with 22 tackles, Rashan Gary has 2.5 sacks and Evan Williams has 1 interception.

Cleveland Browns Betting Preview

The Cleveland Browns lost to the Bengals and Ravens, and they play the Lions next. The Cleveland Browns have lost 8 straight games. Joe Flacco is completing 62.2 percent of his passes for 489 yards, 2 touchdowns, and 3 interceptions. Jerry Jeudy and Harold Fannin Jr. have combined for 228 receiving yards on 21 catches, while David Njoku has 7 receptions.

The Cleveland Browns ground game is averaging 82 yards per contest, and Quinshon Judkins leads the way with 61 yards on 10 carries. Defensively, Cleveland is allowing 29 points and 191.5 yards per game. Devin Bush leads the Cleveland Browns with 15 tackles, Myles Garrett has 3.5 sacks and Greg Newsome II has 2 pass deflections.

Green Bay Packers @ Cleveland Browns Betting Trends: Week 3

Why the Cleveland Browns will win

• The underdogs have won each of the Packers’ last five Week 3 games.
• The Packers have lost each of their last three Week 3 games as road favorites.
• The Packers have failed to cover the spread in seven of their last eight games as favorites against AFC opponents.
• The underdogs have covered the spread in seven of the Packers’ last eight Week 3 games.
• The Browns have scored the first touchdown in each of their last four Week 3 games.
• The home team has won the first half in five of the Packers’ last six games.
• The Packers have lost the first quarter in three of their last four games as favorites against AFC North opponents.

Why the Green Bay Packers will win

• The Browns have lost each of their last eight games.
• The Packers have won each of their last eight September games against AFC opponents.
• The Packers have covered the spread in each of their last six Week 3 games.
• The Browns have failed to cover the spread in seven of their last eight games.
• The Browns have lost the first half in each of their last 10 Sunday games.
• The Browns have lost the first quarter in each of their last six games.
• The Packers have scored the first touchdown in each of their last seven games as road favorites.

Total Points Facts

• Each of the Packers’ last eight road games following a home win have gone OVER the total points line.
• Each of the Browns’ last six games against NFC North opponents have gone UNDER the total points line.
• Each of the last four Sunday games at Huntington Bank Field have gone UNDER the total points line.

Cleveland Browns Player Prop Facts

• Jerry Jeudy has recorded 66+ receiving yards in each of the Browns’ last six home games.
• Jerome Ford has recorded 69+ rushing and receiving yards in four of the Browns’ last five home games against NFC opponents.
• Cedric Tillman has scored the last touchdown in each of his last three Sunday home appearances.
• Joe Flacco has recorded 262+ passing yards in each of his last 10 home appearances as a starter.
• Deshaun Watson has recorded 26+ rushing yards in four of his five previous September appearances against NFC opponents.
• Cedric Tillman has scored at least one touchdown in each of his last four Sunday appearances with the Browns as underdogs.
• Joe Flacco has recorded 25+ completions in each of his last seven Sunday appearances at Huntington Bank Field.
• Heading into Week 3, Myles Garrett ranks T1st in the NFL in sacks (3.5) this season.

Green Bay Packers Player Prop Facts

• Josh Jacobs has scored the first touchdown in three of the Packers’ last four games as road favorites.
• Josh Jacobs has scored at least one touchdown in each of the Packers’ last 11 games.
• Dontayvion Wicks has recorded 30+ receiving yards in each of the Packers’ last five games.
• Josh Jacobs has recorded 92+ rushing and receiving yards in seven of his last eight appearances with his team as a favorite against AFC opponents.
• Jordan Love has recorded 246+ passing yards in five of his last six September appearances.
• Jordan Love has recorded 11+ rushing yards in four of his five previous road appearances against AFC opponents.
• Jordan Love has recorded 21+ completions in six of his last seven appearances against AFC opponents.
• Heading into Week 3, Daniel Whelan ranks 1st amongst qualified players for gross average yards per punt (53.9) this season.

Matchup/League Facts

• Browns – three different players have recorded 60+ receiving yards in a game this season – equal-most in the NFL, heading into Week 3.
• Heading into Week 3, the Browns rank 1st in the NFL in yards allowed per game (191.5) this season.
• Packers – one different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
• Heading into Week 3, the Packers rank 1st in the NFL in average yards per punt (53.9) this season.

Browns vs Packers Prediction

The Browns have been great defensively, which includes being first in total defense and against the run, but it hasn’t resulted in wins due to an offense that’s been terrible. The Browns have lost 8 straight regular season games, and they’re 1-7 ATS in their last 8 games as an underdog.

The Packers look like one of the more balanced teams in the league, and they’ve covered 6 of their last 7 games as a favorite. The hook on top of the key number doesn’t make me feel great, but it would shock nobody if the Packers win this game by double digits. Give me the Packers.