Buffalo Bills vs Indianapolis Colts 11/21/21 NFL Picks, Odds, Predictions
Indianapolis Colts (5-5) vs. Buffalo Bills (6-3)
November 21, 2021 1:00 pm EDT
The Line: Buffalo Bills -7/ Indianapolis Colts +7; Over/Under: -49.5
(Get latest betting odds)
The Buffalo Bills and Indianapolis Colts square off in week 11 NFL action from Highmark Stadium in Orchard Park on Sunday afternoon.
The Indianapolis Colts will be out to build on their 23-17 win over Jacksonville in their last game. Carson Wentz has thrown for 2,378 yards, 17 touchdowns and 3 interceptions on 63.5% passing while Jonathan Taylor leads the Colts on the ground with 937 rushing yards and 9 TDs. Michael Pittman Jr. leads the Colts in receiving with 55 catches for 729 yards and 5 scores while Zach Pascal has 328 receiving yards with 3 scores and Mo Alie-Cox has 4 touchdown grabs with 211 receiving yards this season. On defense, Bobby Okekreke leads the Colts with 86 total tackles while DeForst Buckner has a team-high 4.5 sacks.
The Buffalo Bills will be looking to build on their 45-17 win over the Jets last time out. Josh Allen has thrown for 2,602 yards, 19 touchdowns and 6 INTs on 66.3% passing while Devin Singletary leads the Bills with 398 rushing yards and Allen has 322 rushing yards and 3 scores himself. Stefon Diggs leads Buffalo in receiving with 56 grabs for 750 yards and 4 TDs while Emmanuel Sanders has 505 yards with 4 scores and Cole Beasley has 461 receiving yards. Dawson Knox also has a team-high 5 receiving TDs as well this season. On defense, Tremaine Edmunds leads Buffalo with 55 total tackles while Jorda Poyer has 4 interceptions and Micah Hyde has 3 picks.
Indianapolis is 8-2 ATS in their last 10 road games and 4-1 ATS in their last 5 games as a road underdog while the over is 10-1 in their last 11 games against a team with a winning record. Buffalo is 7-2-1 ATS in their last 10 home games and 14-5-1 ATS in their last 20 games overall while the under is 4-1 in their last 5 games as a home favorite.
I get that the Bills are one of the top teams in the NFL, but if you dig into their record, there’s not really a standout team that’s in there outside of the Chiefs who have struggled big time this season. The Colts see their opening in the AFC South race and need to keep putting forth solid performances if they’re going to eep the division title hopes going. Give me the Colts and the points in this one.