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Buffalo Bills vs Kansas City Chiefs prediction 1-21-24 Picks

Kansas City Chiefs (12-6) vs. Buffalo Bills (12-6)
January 21, 2024 6:30 pm EDT
The Line: Buffalo Bills -2.5; Over/Under: +46.5
(Get latest betting odds)

The Kansas City Chiefs have won their last 3 games and look to make the AFC Championship for a sixth straight season. The Buffalo Bills are riding a 6-game winning streak and hope to make their second AFC Championship in the last 4 years. Let’s preview the AFC Divisional Playoffs and give out a Kansas City Chiefs vs Buffalo Bills prediction.

Kansas City Chiefs Betting Preview

The Kansas City Chiefs are coming off wins over the Bengals, Chargers and Dolphins. Patrick Mahomes is completing 56.1 percent of his passes for 262 yards, 1 touchdown and 0 interceptions. Rashee Rice and Travis Kelce have combined for 201 receiving yards and 1 touchdown, while Justin Watson has 2 receptions. The Kansas City Chiefs ground game is averaging 147 yards per contest, and Isiah Pacheco leads the way with 89 yards and 1 touchdown. Defensively, Kansas City is allowing 7 points and 264 yards per game. Nick Bolton leads the Kansas City Chiefs with 10 tackles, George Karlaftis has 1.5 sacks and Mike Edwards has 1 interception.


Kansas City Chiefs Team Facts

  • The Chiefs have won seven of their last eight Sunday games against teams that held a winning record.
  • The Chiefs have covered the spread in each of their last nine games as road underdogs against AFC opponents.
  • The Chiefs have scored the first touchdown in each of their last six games played on the East Coast.
  • The Chiefs have won the first quarter in three of their last four games against teams that held a winning record.
  • The Chiefs have won the first half in each of their last seven January games against AFC opponents.

Buffalo Bills Betting Preview

The Buffalo Bills have beat the Chiefs, Cowboys, Chargers, Patriots, Dolphins and Steelers during this winning streak. Josh Allen is completing 70 percent of his passes for 203 yards, 3 touchdowns and 0 interceptions. Dalton Kincaid and Stefon Diggs have combined for 111 receiving yards and 1 touchdown, while Deonte Harty has 1 reception. The Buffalo Bills ground game is averaging 179 yards per contest, and James Cook leads the way with 79 yards on 18 carries. Defensively, Buffalo is allowing 17 points and 324 yards per game. A.J. Klein leads the Buffalo Bills with 11 tackles, Greg Rousseau has 1 sack and Kaiir Elam has 1 interception.

Buffalo Bills Team Facts

  • The Bills have won seven of their last eight games at Highmark Stadium against teams that held a winning record.
  • The Bills have covered the spread in each of their last four games against teams that held a winning record.
  • The Bills have won the first half in nine of their last 10 home games against teams that held a winning record.
  • The Bills have scored the first touchdown in eight of their last nine postseason games.
  • The Bills have won the first quarter in each of their last three home games against teams that held a winning record.

Kansas City Chiefs vs Buffalo Bills prediction

The Buffalo Bills are playing their best ball of the season with 6 straight wins, they’re at home, and they’ve managed to beat the Chiefs in 3 of the last 4 meetings. I understand why they’re getting the nod from the oddsmakers. With all that said, we’re getting Patrick Mahomes in the underdog role, something we don’t get often. In fact, Mahomes has been an underdog just 10 times previously, and he’s won 7 of those games while covering 8. This will be the eighth time since 2020 the Chiefs will be underdogs, and they’ve won 5 of those games. You don’t get these chances typically. I say take advantage of it while you can. Give me the Chiefs and the points.

Randy Chambers's Free Pick: Kansas City Chiefs +2.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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