Cardinals vs Lions Prediction 10/11/26 NFL Picks Today

The Detroit Lions and Arizona Cardinals meet Sunday in NFL action at State Farm Stadium. Here’s a Cardinals vs. Lions Prediction. This article will include a Cardinals vs. Lions Pick.

Detroit Lions Betting Preview

The Detroit Lions beat the Jets, lost to the Panthers, and play the Packers next. The Detroit Lions have lost 5 of their last 8 games. Jared Goff is completing 67.7 percent of his passes for 1,214 yards, 9 touchdowns, and 0 interceptions. Amon-Ra St. Brown and Jameson Williams have combined for 532 receiving yards and 5 touchdowns, while Sam LaPorta has 22 receptions.

The Detroit Lions ground game is averaging 102 yards per contest, and Jahmyr Gibbs leads the way with 353 yards and 5 touchdowns. Defensively, Detroit is allowing 31.8 points and 423.8 yards per game. Jack Campbell leads the Detroit Lions with 32 tackles, Aidan Hutchinson has 3.5 sacks, and Derrick Barnes has 1 interception.

Arizona Cardinals Betting Preview

The Arizona Cardinals lost to the Giants and 49ers, and play the Rams next. The Arizona Cardinals have lost 12 of their last 13 games. Jacoby Brissett is completing 67.8 percent of his passes for 818 yards, 6 touchdowns, and 4 interceptions. Trey McBride and Michael Wilson have combined for 500 receiving yards and 3 touchdowns, while Kendrick Bourne has 12 receptions.

The Arizona Cardinals’ ground game is averaging 100.5 yards per contest, and Jeremiyah Love leads the way with 223 yards and 1 touchdown. Defensively, Arizona is allowing 29.3 points and 351.3 yards per game. Jack Gibbens leads the Arizona Cardinals with 32 tackles, Budda Baker has 1.5 sacks, and Andrew Wingard has 1 interception.

Why the Arizona Cardinals will win

• The Cardinals have won eight of their last nine home games against the Lions following a loss.
• The Lions have lost seven of their last eight Week 5 road games against NFC opponents.
• The Cardinals have covered the spread in each of their last seven October games as home underdogs against NFC opponents.
• The Lions have failed to cover the spread in seven of their last eight games without Kerby Joseph.
• The Lions have lost the first quarter in five of their last six games against teams that held a losing record.
• The Lions have lost the first half in seven of their last eight October games against NFC West opponents.
• The Cardinals have scored the first touchdown in four of their last five games following a road loss.

Why the Detroit Lions will win

• The Cardinals have lost each of their last nine games against NFC opponents.
• The Lions have won each of their last six road games without Aidan Hutchinson.
• The Lions have covered the spread in 10 of their last 11 games without Jameson Williams.
• The Cardinals have failed to cover the spread in eight of their last nine home games.
• The favorites have won the first quarter in each of the Cardinals’ last six Week 5 games.
• The favorites have won the first half in each of the Cardinals’ last six Week 5 games.
• The Lions have scored the first touchdown in each of their last four Sunday games played on the West Coast.

Total Points Facts

• Each of the Lions’ last eight Sunday games as favorites have gone OVER the total points line.
• Each of the Cardinals’ last five games without Marvin Harrison Jr. have gone OVER the total points line.
• Nine of the last 11 Sunday games at State Farm Stadium have gone OVER the total points line.

Arizona Cardinals Player Prop Facts

• Trey McBride has scored at least one touchdown in each of the Cardinals’ last seven games as moderate underdogs (+3.5 to +7.0 points).
• Kendrick Bourne has recorded 25+ receiving yards in each of his last seven appearances in games with a total points line of at least 50.0.
• Jacoby Brissett has recorded 10+ rushing yards in each of his last seven October appearances with his team as an underdog.
• Kendrick Bourne has recorded 25+ rushing and receiving yards in each of his last seven appearances in games with a total points line of at least 50.0.
• Heading into Week 5, Jacoby Brissett has thrown the most interceptions in a single game this season (3 vs. the Giants, Week 4).

Detroit Lions Player Prop Facts

• Jahmyr Gibbs has scored the last touchdown in each of the Lions’ last four games as favorites following a road loss.
• Jahmyr Gibbs has scored two or more touchdowns in four of the Lions’ last five games as moderate favorites (-3.5 to -7.0 points).
• Jared Goff has recorded 26+ completions in five of the Lions’ last six games with a total points line of at least 50.0.
• Jahmyr Gibbs has recorded 94+ rushing yards in four of the Lions’ last five games as favorites following a road loss.
• Jameson Williams has recorded 66+ receiving yards in each of the Lions’ last six Sunday road games.
• Jared Goff has recorded 327+ passing yards in each of the Lions’ last four road games with a total points line of at least 50.0.
• Jahmyr Gibbs has scored at least one touchdown in each of the Lions’ last 13 games as favorites with a total points line of at least 50.0.
• Jameson Williams has recorded 66+ rushing and receiving yards in each of the Lions’ last six Sunday road games.
• Heading into Week 5, Jahmyr Gibbs ranks T1st in the NFL in touchdowns (7) this season.

Matchup/League Facts

• Heading into Week 5, the Cardinals have allowed an average of 34.3 points over their last three games – most in the league over that span.
• Heading into Week 5, the Cardinals have allowed an average of 30.8 points over their last five games – most in the league over that span.
• Lions – five different players have recorded 60+ receiving yards in a game this season – tied for most in the NFL, heading into Week 5.
• Lions – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 5.

Cardinals vs Lions Prediction

The Lions have taken a step back dating back to the end of last season, and it feels like the honeymoon has worn off. However, this feels like a good spot for them as they’re fresh off a bad loss to the Panthers and have a bye week coming up. The Cardinals are one of the worst defenses in the league, and the offense doesn’t produce consistently. If the Lions play to their potential, this should be a comfortable road win in the desert. I’ll lay the points.