Cardinals vs Packers Prediction 10/19/25 NFL Picks Today

The Green Bay Packers and Arizona Cardinals meet Sunday in NFL action at State Farm Stadium. Here’s a Cardinals vs Packers Prediction. This article will include a Cardinals vs Packers Pick.

Green Bay Packers Betting Preview

The Green Bay Packers beat the Bengals, tied with the Cowboys, and they play the Steelers next. The Packers have won 12 of their last 18 regular season games. Jordan Love is completing 70.1 percent of his passes for 1,259 yards, 9 touchdowns, and 2 interceptions. Tucker Kraft and Romeo Doubs have combined for 502 receiving yards and 7 touchdowns, while Matthew Goldson has 14 receptions.

The Green Bay Packers ground game is averaging 122.2 yards per contest, and Josh Jacobs leads the way with 359 yards and 6 touchdowns. Defensively, Green Bay is allowing 20.4 points and 280.2 yards per game. Quay Walker leads the Green Bay Packers with 50 tackles, Rashan Gary has 4.5 sacks and Evan Williams has 1 interception.

Arizona Cardinals Betting Preview

The Arizona Cardinals lost to the Titans and Colts, and play the Cowboys next. The Arizona Cardinals have lost 4 straight games. Kyler Murray is completing 68.3 percent of his passes for 962 yards, 6 touchdowns, and 3 interceptions. Trey McBride and Marvin Harrison Jr. have combined for 685 receiving yards and 4 touchdowns, while Zay Jones has 10 receptions.

The Arizona Cardinals ground game is averaging 113.2 yards per contest, and Kyler Murray leads the way with 173 yards and 1 touchdown. Defensively, Arizona is allowing 21.2 points and 348 yards per game. Mack Wilson Sr. leads the Arizona Cardinals with 50 tackles, Josh Sweat has 5 sacks and Dadrion Taylor-Demerson has 2 interceptions.

Why the Arizona Cardinals will win

• The home team has won each of the Cardinals’ last five Week 7 games.
• The Packers have lost three of their last four games as road favorites following a home win.
• The Packers have failed to cover the spread in each of their last six Sunday games against teams that held a losing record.
• The Cardinals have covered the spread in each of their last six October games as home underdogs against NFC opponents.
• The Cardinals have won the first half in each of their last four Sunday home games.
• The Packers have won the first quarter in each of their last eight games as moderate favorites (-3.5 to -7.0 points).
• The Cardinals have scored the first touchdown in each of their last eight Sunday home games.

Why the Green Bay Packers will win

• The Packers have won 10 of their last 11 October games against NFC West opponents.
• The Cardinals have lost each of their last four games.
• The Packers have covered the spread in each of their last seven games against NFC West opponents.
• The Cardinals have failed to cover the spread in each of their last four October games against NFC North opponents.
• The favorites have won the first half in each of the Cardinals’ last eight games.
• The Packers have won the first quarter in 10 of their last 11 October games against NFC West opponents.
• The Packers have scored the first touchdown in each of their last 12 games as favorites against NFC West opponents.

Total Points Facts

• Each of the Cardinals’ last eight games played as underdogs on the West Coast have gone UNDER the total points line.
• Eight of the Packers’ last nine road games following a home win have gone OVER the total points line.
• Each of the last five Sunday games at State Farm Stadium have gone OVER the total points line.

Arizona Cardinals Player Prop Facts

• Trey McBride has scored a touchdown in each of the Cardinals’ last three day games against teams with a winning record.
• Michael Carter has recorded 48+ rushing and receiving yards in each of his last four Sunday appearances.
• Kyler Murray has recorded 220+ passing yards in each of the Cardinals’ last six Sunday home games.
• Elijah Higgins has recorded 11+ receiving yards in each of the Cardinals’ last five Sunday games as home underdogs.
• Kyler Murray has recorded 20+ rushing yards in each of his last nine appearances with the Cardinals as underdogs following a loss.
• Kyler Murray has recorded 23+ completions in each of his last seven appearances following a loss.
• Trey McBride has recorded the equal-most targets (53) of any player yet to record a drop this season.

Green Bay Packers Player Prop Facts

• Josh Jacobs has scored the first touchdown in each of his last three road appearances against NFC West opponents.
• Jordan Love has recorded 12+ rushing yards in each of the Packers’ last four games.
• Josh Jacobs has scored at least one touchdown in each of the Packers’ last 11 games against NFC opponents.
• Josh Jacobs has recorded 106+ rushing and receiving yards in each of the Packers’ last four games as moderate favorites (-3.5 to -7.0 points).
• Jordan Love has recorded 258+ passing yards in four of the Packers’ last five games as moderate favorites (-3.5 to -7.0 points).
• Josh Jacobs has recorded 42+ receiving yards in each of the Packers’ last four games as road favorites.
• Jordan Love has recorded 20+ completions in three of the Packers’ last four road games against NFC opponents.
• Heading into Week 7, Romeo Doubs has recorded the equal-most receiving touchdowns in a single game this season (3 vs Cowboys, Week 4).

Matchup/League Facts

• Cardinals – 10 different players have recorded at least one touchdown this season – equal-most in the NFL, heading into Week 7.
• Heading into Week 7, the Cardinals rank 1st in the NFL in Q3 opponent points per game (2.0) this season.
• Heading into Week 7, the Packers rank 1st in the NFL in rushing yards allowed per game (73.0) this season.
• Heading into Week 7, the Packers rank 1st in the NFL in 3rd down percentage (52.3%) this season.

Cardinals vs Packers Prediction

The Cardinals are free-falling and not a team I’m excited to back right now. The Cardinals aren’t producing to their potential offensively, the defense gets gashed through the air, and Murray remains questionable with a foot injury. On paper the Packers are one of the best teams in the league as they’re a balanced attack and top-10 in scoring offense, total offense, scoring defense and total defense.

We have a team that’s looking more and more like a title contender against a team that can’t get out of its own way and has a banged up quarterback. You could argue the Packers should be larger favorites. Give me the road team by a touchdown.