Cardinals vs Rams Prediction 12/7/25 NFL Picks Today
LA Rams (9-3) vs. Arizona Cardinals (3-9)
December 7, 2025 4:25 pm EDT
The Line: Arizona Cardinals +8.5; Over/Under: 47.5
(Get latest betting odds)
The Los Angeles Rams and Arizona Cardinals meet Sunday in NFL action at State Farm Stadium. Here’s a Cardinals vs Rams Prediction. This article will include a Cardinals vs Rams Pick.
Los Angeles Rams Betting Preview
The Los Angeles Rams beat the Buccaneers, lost to the Panthers, and they play the Lions next. The Rams have won 6 of their last 7 games. Matthew Stafford is completing 66.3 percent of his passes for 3,073 yards, 32 touchdowns, and 4 interceptions. Puka Nacua and Davante Adams have combined for 1,708 receiving yards and 18 touchdowns, while Colby Parkinson has 26 receptions.
The Los Angeles Rams ground game is averaging 113.5 yards per contest, and Kyren Williams leads the way with 868 yards and 7 touchdowns. Defensively, Los Angeles is allowing 17.5 points and 315.1 yards per game. Nate Landman leads the Los Angeles Rams with 106 tackles, Byron Young has 10 sacks and Emmanuel Forbes Jr. has 3 interceptions.
Arizona Cardinals Betting Preview
The Arizona Cardinals lost to the Jaguars and Buccaneers, and play the Texans next. The Arizona Cardinals have lost 4 straight games. Jacoby Brissett is completing 67.6 percent of his passes for 2,188 yards, 13 touchdowns, and 4 interceptions. Trey McBride and Marvin Harrison Jr. have combined for 1,473 receiving yards and 12 touchdowns, while Michael Wilson has 50 receptions.
The Arizona Cardinals ground game is averaging 100.6 yards per contest, and Bam Knight leads the way with 255 yards and 4 touchdowns. Defensively, Arizona is allowing 25.3 points and 332.2 yards per game. Budda Baker leads the Arizona Cardinals with 87 tackles, Josh Sweat has 11 sacks and Dadrion Taylor-Demerson has 2 interceptions.
Why the Arizona Cardinals will win
- The underdogs have won three of the Rams’ last four Week 14 games.
- The Rams have lost two of their last three games as heavy favorites (>-7.0 points).
- The Cardinals have covered the spread in each of their last six games as underdogs without Michael Carter.
- The Rams have failed to cover the spread in three of their last four games as favorites against NFC West opponents.
- The Rams have lost the first quarter in three of their last four games as heavy favorites (>-7.0 points).
- The Cardinals have won the first half in six of their last seven Sunday home games.
- The Cardinals have scored the first touchdown in nine of their last 11 Sunday home games.
Why the Los Angeles Rams will win
- The Cardinals have lost each of their last 10 December home games against NFC West opponents.
- The Rams have won each of their last eight games in December.
- The Cardinals have failed to cover the spread in each of their last 10 December home games against NFC West opponents.
- The Rams have covered the spread in each of their last six road games against teams that held a losing record.
- The Rams have won the first quarter in five of their last six games.
- The Cardinals have lost the first half in each of their last 10 games as underdogs against NFC West opponents.
- The Rams have scored the first touchdown in each of their last seven games.
Total Points Facts
- Each of the Cardinals’ last eight Sunday home games have gone OVER the total points line.
- Eight of the Rams’ last nine games as favorites following a loss have gone UNDER the total points line.
- Eighteen of the last 22 Sunday games at State Farm Stadium have gone OVER the total points line.
Arizona Cardinals Player Prop Facts
- Trey McBride has scored at least one touchdown in seven of the Cardinals’ last eight games as underdogs against NFC opponents.
- Jacoby Brissett has recorded 25+ completions in five of the Cardinals’ last six Sunday games.
- Jacoby Brissett has recorded 16+ rushing yards in five of the Cardinals’ last six Sunday games.
- Jacoby Brissett has recorded 258+ passing yards in each of the Cardinals’ last seven games.
- Elijah Higgins has recorded 17+ receiving yards in each of the Cardinals’ last six December games as underdogs.
- Michael Carter has recorded 28+ rushing and receiving yards in each of his last six appearances following a loss.
- Heading into Week 14, Trey McBride ranks 1st in the NFL in receptions (88) this season.
Los Angeles Rams Player Prop Facts
- Colby Parkinson has scored a touchdown in each of the Rams’ last three games played on the West Coast.
- Colby Parkinson has recorded 27+ receiving yards in three of the Rams’ last four games.
- Blake Corum has recorded 42+ rushing yards in four of his last five road appearances against NFC opponents.
- Blake Corum has recorded 53+ rushing and receiving yards in each of the Rams’ last three road games against NFC opponents.
- Matthew Stafford has recorded 287+ passing yards in each of his last three Week 14 appearances.
- Matthew Stafford has recorded 23+ completions in each of his last four Week 14 appearances.
- Heading into Week 14, Matthew Stafford ranks 1st in the NFL in passing touchdowns (32) this season.
Matchup/League Facts
- Heading into Week 14, the Cardinals have suffered the equal-most losses when leading after Q3 this season (5).
- Heading into Week 14, the Cardinals have suffered the equal-most losses when leading at HT this season (5).
- Rams – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 14.
- Heading into Week 14, the Rams rank 32nd in the NFL in kickoff return yards per game (74.3) this season.
Cardinals vs Rams Prediction
The Cardinals aren’t winning games and are a below average team on both sides of the ball, so you can make a case for the points. However, the Rams haven’t lost two straight games this season, and I’m sure they’ll be eager to rebound from a bad loss to the Panthers. The Rams are a top-10 team in scoring offense and scoring defense, and they’re a profitable 8-4 ATS on the season. Only the Seahawks have a better cover percentage than the Rams. This feels like a bounce back game for the Rams, arguably the most consistent team in the league. I’ll lay the points.