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Chiefs vs Seahawks Prediction 10/25/26 NFL Picks Today

Kansas City Chiefs (5-0) vs. Seattle Seahawks (3-3)
October 25, 2026 8:20 pm EDT
The Line: Seattle Seahawks -3; Over/Under: 42.5
(Get latest betting odds)

In this article, we will formulate a Chiefs vs Seahawks Prediction for this NFL Week 6 game on Sunday, October 25th. Let’s take a look at the prediction for this NFL matchup.

Seattle Seahawks Preview

The Seattle Seahawks have a 3-3 record this season are sitting on the 2nd place of the NFC West. They are coming off a 14-17 road loss against the Broncos and will face the Bears, the Cardinals and the Raiders next.

Offensively, the Seahawks average 24.7 points per game, ranking 13th in the NFL, while defensively, they allow 20.3 points per game, which is 7th. Seattle averages 332.2 total yards per game (225 passing and 107.2 rushing), while allowing 237.3 total yards per game (96 rushing and 141.3 passing).

Sam Darnold leads the Seahawks with 1033 passing yards with 60.4% completed passes and seven touchdowns. Emanuel Wilson leads the team in rushing yards with 303, while Jaxon Smith-Njigba has 49 receptions for a team-high 717 receiving yards. Defensively, Ernest Jones has a team-high 59 total tackles (31 of them solo), while Byron Murphy, Leonard Williams and Ernest Jones lead the team in sacks, with 3 each.

Kansas City Chiefs Preview

The Kansas City Chiefs have a 5-0 record this season are sitting on the 1st place of the AFC West. They are coming off a 22-6 home win against the Chargers and will face the Broncos, the Jets and the Falcons next.

Offensively, the Chiefs average 28 points per game, ranking 5th in the NFL, while defensively, they allow 16.6 points per game, which is 2nd. Kansas City averages 414 total yards per game (254.2 passing and 159.8 rushing), while allowing 306 total yards per game (88.8 rushing and 217.2 passing).

Patrick Mahomes leads the Chiefs with 1309 passing yards with 66.5% completed passes and nine touchdowns. Kenneth Walker III leads the team in rushing yards with 665, while Travis Kelce has 20 receptions for a team-high 299 receiving yards. Defensively, Nick Bolton has a team-high 48 total tackles (23 of them solo).

Kansas City Chiefs @ Seattle Seahawks Betting Trends: Week 7

 

Why the Seattle Seahawks will win

  • The Seahawks have won each of their last seven games when playing with a rest advantage.
  • The Chiefs have lost five of their last six games without Jalen Royals.
  • The Seahawks have covered the spread in each of their last seven games when playing with a rest advantage.
  • The Chiefs have failed to cover the spread in each of their last six games without Jalen Royals.
  • The Seahawks have won the first quarter in eight of their last nine games against teams that held a winning record.
  • Reigning Super Bowl champions have won the first half in each of their last six Week 7 games.
  • The Seahawks have scored the first touchdown in each of their last eight home games against AFC West opponents.

Why the Kansas City Chiefs will win

  • The Chiefs have won each of their last 11 games against NFC opponents on a losing streak.
  • The Seahawks have lost three of their last four games as favorites.
  • The Chiefs have covered the spread in each of their last nine October games against NFC opponents.
  • The Seahawks have failed to cover the spread in seven of their last eight games as favorites against AFC West opponents.
  • The Chiefs have won the first half in 10 of their last 11 Week 7 games.
  • The Seahawks have lost the first quarter in each of their last four night games at Lumen Field following a loss.

Total Points Facts

  • Each of the Seahawks’ last six October games as home favorites have gone OVER the total points line.
  • Eight of the Chiefs’ last nine games without Jalen Royals have gone UNDER the total points line.
  • Each of the last five Sunday night games between teams from different conferences have gone OVER the total points line.

Seattle Seahawks Player Prop Facts

  • Jaxon Smith-Njigba has scored at least one touchdown in each of the Seahawks’ last seven home games against teams on a winning streak.
  • Sam Darnold has recorded 240+ passing yards in seven of his last eight appearances following a loss.
  • Cooper Kupp has recorded 32+ receiving yards in each of his 10 previous appearances in night games against AFC opponents.
  • Sam Darnold has recorded 21+ completions in three of the Seahawks’ last four night games.
  • Cooper Kupp has recorded 32+ rushing and receiving yards in each of his 10 previous appearances in night games against AFC opponents.
  • Heading into Week 7, Jaxon Smith-Njigba ranks 1st in the NFL in receiving yards (717) this season.

Kansas City Chiefs Player Prop Facts

  • Kenneth Walker III has scored two touchdowns in four of the Chiefs’ last five games.
  • Kenneth Walker III has recorded 111+ rushing and receiving yards in each of his last six appearances on the West Coast.
  • Kenneth Walker III has recorded 29+ receiving yards in each of his last five appearances against NFC West opponents.
  • Kenneth Walker III has scored at least one touchdown in each of his last four appearances with his team as a road underdog against NFC opponents.
  • Justin Fields has recorded 46+ rushing yards in each of his last seven October appearances with his team as an underdog against NFC opponents.
  • Heading into Week 7, Kenneth Walker III ranks 1st in the NFL in rushing yards (665) this season.

Matchup/League Facts

  • Heading into Week 7, the Seahawks rank 1st in the NFL in yards allowed per game (237.3) this season.
  • Heading into Week 7, the Seahawks rank 1st in the NFL in passing yards allowed per game (141.3) this season.
  • Heading into Week 7, the Chiefs rank 1st in the NFL in yards per game (414.0) this season.
  • Heading into Week 7, the Chiefs are the only team to average over 250.0 passing yards and 125.0 rushing yards this season.

Chiefs vs Seahawks Prediction

In this Chiefs vs Seahawks Prediction, the Seahawks are coming as -2.5 home favorites. The Chiefs have been undefeated this season but they have been banged up and entering this game as +2.5 road dogs. The Chiefs are a top-5 team in football both offensively and defensively but the Seahawks also have the 7th-best defense in the league, as both teams allow just 36.9 points per game combined this season. Given the fact that the offensive line of the Chiefs is stripped of its depth, I will not pick a side and expect a low-scoring affair today. Both teams are coming off very low-scoring games, with 28 and 31 total points, so take the under 42.5 points in this one.

Nikos Lagouretos's Free Pick: Under 42.5

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