Colts vs Titans Prediction 10/18/26 NFL Picks Today

In this article we will formulate a Colts vs Titans prediction for this NFL game on Sunday, October 18th at Lucas Oil Stadium in Indianapolis, Indiana. Let’s take a look at the prediction for this week 6 matchup.

Indianapolis Colts Betting Preview

The Indianapolis Colts are 2-3 this year after they lost to the Steelers by a score of 34-22 in their last game. Indianapolis trailed 17-13 at halftime and just 24-22 in the fourth, but they allowed the last 10 points for the loss. The Colts were out gained by a total of 352-332, went 4-15 on third downs, and tied the turnover battle at zero in the game. Daniel Jones threw for 267 yards, while Tyler Warren caught seven passes for 83 yards. Jonathan Taylor rushed 15 times for 45 yards in the loss. 

Prior to that game, Indianapolis defeated the Commanders by a score of 30-13 and the Texans by a score of 19-17. The Colts have scored 24.8 points per game with 193.0 passing yards and 100.8 rushing yards per game, while they have allowed 27.6 points against per game this season. Daniel Jones has thrown for 1,021 yards with three touchdowns and four interceptions this year. 

Tennessee Titans Betting Preview

The Tennessee Titans are 0-5 this season after they lost to the Texans by a score of 26-3 in their last game. Tennessee trailed 12-3 at halftime and they were shutout in the second half in the ugly loss. The Titans were out gained by a total of 329-187, went 4-11 on third downs, and lost the turnover battle by a total of 2-0 in the game. Cam Ward threw for 170 yards and one interception, while Wan’Dale Robinson caught six passes for 53 yards. Tony Pollard rushed 14 times for 52 yards in the game. 

Prior to that loss, Tennessee lost to the Ravens by a score of 24-18 and the Giants by a score of 12-7. The Titans have scored 11.6 points per game with 163.8 passing yards and 82.6 rushing yards per game, while they have allowed 21.8 points against per game this season. Cam Ward has thrown for 896 yards with three touchdowns and three interceptions this season, while Carnell Tate has caught 23 passes for 274 yards. Tony Pollard has rushed 68 times for 273 yards and one score this year. 

Why the Indianapolis Colts will win

• The Titans have lost each of their last 11 games against AFC South opponents.
• The Colts have won each of their last 10 home games against AFC opponents on a losing streak.
• The Colts have covered the spread in each of their last six games against the Titans.
• The Titans have failed to cover the spread in 10 of their last 11 games against AFC South opponents.
• The Titans have lost the first quarter in three of their last four road games against teams that held a losing record.
• The Colts have scored the first touchdown in each of their last eight games at Lucas Oil Stadium.
• The Titans have lost the first half in each of their last 13 road games.

Why the Tennessee Titans will win

• The Colts have lost each of their last six games without DeForest Buckner.
• The Titans have won each of their last two games as road underdogs following a Division game.
• The Titans have covered the spread in each of their last four games as underdogs following a Division game.
• The Colts have failed to cover the spread in six of their last seven home games without Andrew Ogletree.
• The Colts have lost the first half in four of their last five games as favorites.
• The Colts have lost the first quarter in four of their last five October games as favorites against AFC opponents.
• The Titans have scored the first touchdown in each of their last four games following a home loss.

Total Points Facts

• Each of the Titans’ last six games against the Colts following a home loss have gone OVER the total points line.
• Eight of the Colts’ last nine games as favorites against the Titans have gone OVER the total points line.
• Three of the last four Sunday games at Lucas Oil Stadium have gone UNDER the total points line.

Indianapolis Colts Player Prop Facts

• Anthony Richardson has scored a touchdown in three of his four previous home appearances against AFC South opponents.
• Nick Westbrook-Ikhine has recorded 10+ receiving yards in 12 of his last 14 appearances with his team as a favorite following a loss.
• Heading into Week 6, Spencer Shrader ranks 1st in the NFL in made field goals (16) this season.

Tennessee Titans Player Prop Facts

• Wan’Dale Robinson has scored a touchdown in each of his last three Sunday appearances with his team as a road underdog.
• Cam Ward has recorded 222+ passing yards in each of the Titans’ last four October road games.
• Calvin Ridley has recorded 28+ receiving yards in each of his 16 previous road appearances against division opponents.
• Cam Ward has recorded 20+ completions in each of the Titans’ last six October games.
• Michael Carter has recorded 25+ rushing yards in each of his last six appearances against AFC opponents.
• Calvin Ridley has recorded 30+ rushing and receiving yards in each of his 16 previous road appearances against division opponents.
• Heading into Week 6, Carnell Tate has the equal-most targets without a receiving touchdown this season (37).

Matchup/League Facts

• Colts – five different players have recorded 60+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
• Heading into Week 6, the Colts rank 1st in the NFL in average kickoff return (29.8 yards) this season.
• Heading into Week 6, the Titans rank 32nd in the NFL in points per game (11.6) this season.
• Heading into Week 6, the Titans rank 32nd in the NFL in yards per game (246.4) this season.

Colts vs Titans Prediction 

Tennessee comes into this game looking for their first win of the season, but they have scored 10 points or fewer in three of their five games. The Titans are 0-2 on the road this year, while the Colts are 1-1 at home. Indianapolis has won two of their last three games, but played pretty poorly last week against Pittsburgh. The Colts have allowed 33+ points in three of their five games, but I don’t trust the Titans or Cam Ward to score consistently. Take the Colts to cover at home.