Jacksonville Jaguars vs LA Rams Prediction 10/19/25 NFL Picks Today
LA Rams (4-2) vs. Jacksonville Jaguars (4-2)
October 19, 2025 9:30 am EDT
The Line: Jacksonville Jaguars +3; Over/Under: 44.5
(Get latest betting odds)
The Los Angeles Rams and the Jacksonville Jaguars meet in week 7 NFL action from Wembley Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Rams vs. Jacksonville Jaguars prediction.
Los Angeles Rams Recap
The Los Angeles Rams come into this game looking to build on their 17-3 win over Baltimore last time out to improve to 4-2 on the year. After this game, Los Angeles will have a bye before playing the New Orleans Saints at home.
Rams Alternate Wins & Losses In 5 Straight
Matthew Stafford has thrown for 1,684 yards, 12 touchdowns and 2 interceptions on 66.5% passing while Kyren Williams has rushed for 418 yards and 2 touchdowns to lead the Rams on the ground. Puka Nacua has a team-high 54 catches for 616 yards while Davante Adams has 26 grabs for 396 yards and 3 touchdowns. Four more Rams have 100+ receiving yards as well this season. On defense, Nate Landman has a team-high 58 total tackles including 30 solo tackles. Byron Young has a team-high 7.5 sacks while the Rams’ defense as a whole has combined for 19 sacks and 4 interceptions so far this season.
Why the Los Angeles Rams will win
- The Rams have won each of their last 14 Sunday games as favorites.
- The Jaguars have lost nine of their 10 previous October games against NFC West opponents.
- The Rams have covered the spread in each of their last eight Sunday games as favorites.
- The Jaguars have failed to cover the spread in seven of their last eight games against NFC West opponents.
Los Angeles Rams Player Prop Facts
- Kyren Williams has scored the first touchdown in each of his three previous October appearances against AFC opponents.
- Matthew Stafford has recorded 23+ completions in five of the Rams’ last six games against AFC South opponents.
- Kyren Williams has recorded 72+ rushing yards in 12 of his last 16 Sunday appearances.
- Matthew Stafford has recorded 252+ passing yards in 10 of his last 11 appearances against AFC South opponents.
- Kyren Williams has scored at least one touchdown in each of his last six October appearances.
- Kyren Williams has scored the last touchdown in three of his last four October appearances with the Rams as favorites.
- Kyren Williams has recorded 14+ receiving yards in each of the Rams’ last five games.
- Kyren Williams has recorded 87+ rushing and receiving yards in each of the Rams’ last four games.
- Heading into Week 7, Matthew Stafford ranks 1st in the NFL in passing yards (1684) this season.
Jacksonville Jaguars Recap
The Jacksonville Jaguars come into this game looking to bounce back from a 20-12 loss at the hands of the Seattle Seahawks last time out to sit at 4-2 this season. After this game, Jacksonville will head on the road for a game against the Las Vegas Raiders.
Jaguars Have Three-Game Win Streak Snapped
Trevor Lawrence has thrown for 1,324 yards, 8 touchdowns and 5 interceptions on 61.1% passing while Travis Etienne Jr. leads the Jaguars on the ground with 470 rushing yards and 2 touchdowns. Brian Thomas Jr. has a team-high 24 catches for 334 yards and a touchdown while Brenton Strange has 204 receiving yards. Travis Hunter, Dyami Brown and Parker Washington all have 100+ receiving yards as well this season. On defense, Foyesade Oluokun has a team-high 53 total tackles while Devin Lloyd has a team-high 4 interceptions. Arik Armstead also has 3.5 sacks to lead the Jaguars. Jacksonville’s defense as a whole has combined for 8 sacks and 10 interceptions so far this season.
Why the Jacksonville Jaguars will win
- The Jaguars have won four of their last five games as underdogs at neutral venues.
- The Rams have lost four of their last five games following a win.
- The Jaguars have covered the spread in five of their last six games following a loss.
- The Rams have failed to cover the spread in each of their last three Week 7 games.
Jacksonville Jaguars Player Prop Facts
- Brian Thomas has scored at least one touchdown in four of the Jaguars’ last five games as slight underdogs (<+3.5 points).
- Trevor Lawrence has recorded 234+ passing yards in each of the Jaguars’ last three October games against NFC opponents.
- Travis Etienne has recorded 15+ receiving yards in seven of the Jaguars’ last eight Sunday games as underdogs.
- Dawuane Smoot has recorded the equal-most defensive targets of any player (2) yet to allow a completion this season.
Total Points Facts
- Each of the Rams’ last nine Week 7 games have gone UNDER the total points line.
- Each of the Jaguars’ last six games following a loss have gone UNDER the total points line.
- Eight of the last nine Sunday games at Wembley Stadium have gone UNDER the total points line.
Los Angeles Rams vs. Jacksonville Jaguars Prediction
I’m on the under here. I get the case to be made for either team, but I think these are two teams that don’t get enough credit for how solid they’ve been defensively up to this point in the year. This to me feels like a 23-20 kind of game that just sneaks in under the number regardless of which way it goes. Give me the under.