NFL Picks

Kansas City Chiefs vs Buffalo Bills 10/16/22 NFL Picks, Predictions, Odds

Buffalo Bills (4-1) vs. Kansas City Chiefs (4-1)
October 16, 2022 4:25 pm EDT
The Line: Kansas City Chiefs +2.5 / Buffalo Bills -2.5; Over/Under: +53.5
(Get latest betting odds)

The Kansas City Chiefs and Buffalo Bills square off Sunday in a week 6 NFL game from Arrowhead Stadium.

The Buffalo Bills will look to build on back-to-back wins after a 38-3 win over the Steelers to improve to 4-1 on the year as a result. Josh Allen has thrown for 1,651 yards, 14 touchdowns and 4 interceptions on 66.8% passing while also leading the Bills on the ground with 225 rushing yards this season. Stefon Diggs leads Buffalo’s receiving group with 39 grabs for 508 yards and 5 TDs while Gabriel Davis has 309 receiving yards and 3 TDs as well this season. Three other Bills have 100+ receiving yards as well on the year. On defense, Matt Milano has a team-high 29 total tackles while Von Miller and Greg Rousseau each have a team-high 4 sacks this season.

The Kansas City Chiefs will try to build on back-to-back wins of their own after also climbing to 4-1 with a narrow 30-29 win over Las Vegas on Monday night last time out. Patrick Mahomes has thrown for 1,398 yards, 15 touchdowns and 2 interceptions on 66.7% passing while Clyde Edwards-Helaire has a team-high 223 rushing yards and a pair of touchdowns. Travis Kelce leads KC’s receiving group with 33 grabs for 347 receiving yards and 7 TDs while JuJu Smith-Schuster has 257 receiving yards as well. Marquez Valdes-Scantling also has 258 receiving yards and Mecole Hardman and the aforementioned Edwards-Helaire each have 100+ receiving yards as well this season. On defense, Nick Bolton has a team-high 37 total tackles with a pair of sacks while L’Jarius Snead has a team-high 3 sacks as well this season.

Buffalo is 7-2-2 ATS in their last 11 games overall and 2-5-1 ATS in their last 8 games against a team with a winning record while the under is 6-2 in their last 8 October games. Kansas City is 6-2 ATS in their last 8 home games and 7-3 ATS in their last 10 games against a team with a winning record while the over is 10-3 in their last 13 games overall.

I get the case to be made across the board in this one but I’m not sure where else to look but the over. KC’s offense is alive once again and should feast on a banged up Bills secondary, while Buffalo looked really good against the Steelers last week and have more than enough offensive firepower to match scores with the Chiefs here. Get your popcorn. This one’s going to be good. Give me the over.

Chris Ruffolo's Free Pick: Over 53.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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