Chiefs vs Eagles Prediction 9/14/25 NFL Picks Today

The Philadelphia Eagles and the Kansas City Chiefs meet Sunday in NFL action from Arrowhead Stadium. Here’s a Chiefs vs Eagles prediction. We will look at this from a betting perspective and determine the best Chiefs vs Eagles pick.

Philadelphia Eagles Betting Preview

The Eagles had a pretty good showing overall in the preseason, going 2-1 despite a couple of tepid efforts scoring-wise. Philly opened things up with a 34-27 victory over the Cincinnati Bengals, but then took their first exhibition defeat with a 22-13 outcome against the Cleveland Browns. Game three was another victory however as Philadelphia powered out a 19-17 road win over the New York Jets. In that one Philly’s Kyle McCord threw for 136 yards and a pick on 15-of-35 passing. Montrell Johnson led the rush with 15 carries for 57 yards and a touchdown, while Terrace Marshall topped the receivers on five catches for 51 yards.

In their season-opening matchup versus the rival Dallas Cowboys on Thursday, Philadelphia had a battle on their hands following a 21-20 advantage in the first half. The Eagles could only muster a field goal in the second, but that was enough in a 24-20 victory. Quarterback Jalen Hurts was 19-of-23 for 152 yards and also led the rushing attack with 14 carries for 62 yards and two touchdowns. Saquon Barkley carried 18 times for 60 yards and a score of his own, and Jahan Dotson was the top receiver with three catches for 59 yards.

Kansas City Chiefs Betting Preview

Over on the Chiefs’ side, they went 0-3 during the preseason and gave up quite a bit scoring-wise along the way. Kansas City hasn’t won a game since the Conference Championships against Buffalo back on January 26, but we’ll get to that in a minute. In exhibition play the Chiefs lost to the Cardinals 20-17, the Seahawks 33-16 and the Bears 29-27 this year. In the matchup with Chicago, Kansas City was up 20-10 at the break and 27-10 by the end of the third quarter. After a 19-0 run from there however, the Chiefs had a preseason loss. QB Patrick Mahomes was 8-of-13 for 143 yards and a score in that one, and Tyquan Thornton’s 58-yard catch put him atop the receivers for the day.

In their Week 1 matchup versus the Los Angeles Chargers on Friday, the Chiefs were down 13-6 going into the second half. Kansas City couldn’t make the comeback from there and eventually fell 27-21 by game’s end. Mahomes was 24-of-39 for 258 yards and a touchdown this time, while also leading the rush with 57 yards and a touchdown on six carries. Hollywood Brown was the team’s leading receiver with 10 catches for 99 yards in all. JuJu Smith-Schuster added five catches for 55 yards, and Travis Kelce caught the touchdown.

Philadelphia Eagles @ Kansas City Chiefs Betting Trends: Week 2

Why the Kansas City Chiefs will win

• The Chiefs have won each of their last 12 games at GEHA Field at Arrowhead Stadium.
• The Eagles have lost each of their last three Week 2 games as road favorites.
• The Chiefs have covered the spread in each of their last seven games as underdogs following a loss.
• The Eagles have failed to cover the spread in seven of their last eight Week 2 games.
• The Chiefs have won the first half in seven of their last eight home games.
• The Chiefs have scored the first touchdown in each of their last five home games.
• The Chiefs have won the first quarter in each of their last eight home games against reigning Super Bowl champions.

Why the Philadelphia Eagles will win

• The Eagles have won each of their last nine games against AFC opponents.
• The Chiefs have lost three of their last four games against NFC East opponents on a winning streak.
• The Eagles have covered the spread in eight of their last nine games as favorites following a Division win.
• The Chiefs have failed to cover the spread in five of their last six Sunday games against teams that held a winning record.
• Reigning Super Bowl Champions have won the first quarter in each of their last six Week 2 games.
• The Eagles have won the first half in each of their last 13 Sunday games.
• The Eagles have scored the first touchdown in each of their last nine games as favorites against AFC opponents.

Total Points Facts

• Seven of the Chiefs’ last eight September games as underdogs have gone OVER the total points line.
• Four of the Eagles’ last five road openers as favorites have gone OVER the total points line.

Kansas City Chiefs Player Prop Facts

• Marquise Brown has scored a touchdown in each of his five previous home appearances against NFC East opponents.
• Elijah Mitchell has recorded 62+ rushing and receiving yards in each of his six previous appearances with his team as an underdog.
• Rashee Rice has recorded 64+ receiving yards in seven of his last eight Sunday regular season appearances.
• Kareem Hunt has recorded 49+ rushing yards in each of his last six appearances with the Chiefs as underdogs.
• Patrick Mahomes has recorded 26+ completions in five of the Chiefs’ last six regular season home games.
• Heading into Week 2, Marquise Brown ranks T1st in the NFL in receptions (10) this season.

Philadelphia Eagles Player Prop Facts

• Jalen Hurts has scored two or more touchdowns in four of the Eagles’ last five road games against teams with a losing record.
• DeVonta Smith has scored a touchdown in each of his last six appearances against AFC opponents.
• Saquon Barkley has recorded 111+ rushing and receiving yards in seven of the Eagles’ last eight road games.
• DeVonta Smith has recorded 64+ receiving yards in each of his last seven appearances against AFC opponents.
• Jalen Hurts has recorded 221+ passing yards in five of the Eagles’ last six games against AFC opponents.
• Saquon Barkley has recorded 118+ rushing yards in seven of his last eight Sunday appearances with the Eagles as favorites.
• Jalen Hurts has recorded 19+ completions in five of the Eagles’ last six September games.
• Heading into Week 2, Jalen Hurts ranks T1st in the NFL in touchdowns (2) this season.

Matchup/League Facts

• Chiefs – one different players have recorded 2.0 sacks or more in a game this season – equal-most in the NFL, heading into Week 2.
• Heading into Week 2, the Chiefs rank T1st in the NFL in 4th down percentage (100.0%) this season.
• Eagles – one different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 2.
• Eagles – two different players have recorded 50+ rushing yards in a game this season – equal-most in the NFL, heading into Week 2.

Chiefs vs Eagles Prediction

I’m staying with Philly. Regardless of the outcome however, this Super Bowl rematch should be a fun one to watch. The Eagles had some major issues in their season-opening win over Dallas, namely nine penalties for 110 yards and just three points in the second half. It was enough to get the win thanks to some opportunistic defense however, and Philadelphia held the ball for 34:52 as opposed to Dallas’ 25:08. Otherwise, the offensive numbers were pretty pedestrian: 302 total yards (144 passing), 4.9 yards per play and 20 first downs. I’d like to see a little more fire in the proverbial belly this weekend.

As for the Chiefs, they need to find a running game in Week 2. Mahomes accounted for 57 of the team’s 98 rushing yards, and KC went just 5-of-14 on third-down tries. The 10 penalties for 71 yards didn’t help matters either. I like a cleaner effort in this one, but I don’t think Kansas City will stay close enough to cover.