LA Rams vs Arizona Cardinals Prediction 10/18/26 NFL Picks Today

The Arizona Cardinals and the Los Angeles Rams meet in week 6 NFL action from SoFi Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Cardinals vs. Los Angeles Rams prediction.

Arizona Cardinals Recap

The Arizona Cardinals come into this game looking to bounce back from a 45-21 loss at the hands of the Detroit Lions last time out to sit at 1-4 this season. After this game, the Cardinals will head home for a game against the Denver Broncos.

Cardinals Drop 4 Straight

Jacoby Brissett has thrown for 1,110 yards, 9 touchdowns and 5 interceptions on 66.3% passing while Jeremiyah Love leads the Arizona Cardinals in rushing with 245 yards and a touchdown. Tyler Allgeier sits behind Love on the ground with 119 yards and a touchdown. Trey McBride leads the Cardinals in receiving with 308 yards and 42 catches along with 3 touchdowns, while Michael Wilson trails with 288 yards and 29 catches along with a touchdown. On defense, Budda Baker has a team-high 36 tackles while the Cardinals’ defense as a whole has combined for 11 sacks and 3 interceptions.

Los Angeles Rams Recap

The Los Angeles Rams come into this game looking to bounce back from a 37-34 loss at the hands of the Buffalo Bills last time out to sit at 2-3 this season. After this game, the Rams will head on the road for a game against the Las Vegas Raiders.

Rams Alternate Wins & Losses In First 5 Games

Matthew Stafford has thrown for 1,572 yards, 9 touchdowns and 6 interceptions on 64.4% passing while Kyren Williams leads the Los Angeles Rams in rushing with 343 yards and 4 touchdowns. Blake Corum sits behind Williams on the ground with 181 yards and a touchdown. Davante Adams leads the Rams in receiving with 441 yards and 27 catches along with 4 touchdowns, while Puka Nacua trails with 337 yards and 31 catches along with a touchdown. On defense, Nate Landman has a team-high 41 tackles while the Rams’ defense as a whole has combined for 8 sacks and 4 interceptions.

Arizona Cardinals @ Los Angeles Rams Betting Trends: Week 6

Why the Los Angeles Rams will win

• The Cardinals have lost each of their last 12 day games against NFC opponents.
• The Rams have won each of their last eight home games against starting rookie QBs.
• The Rams have covered the spread in each of their last eight home games against starting rookie QBs.
• The Cardinals have failed to cover the spread in seven of their last eight October road games against NFC opponents.
• The Cardinals have lost the first half in each of their last eight road games against NFC West opponents.
• The Rams have scored the first touchdown in each of their last seven Week 6 day games.
• The Cardinals have lost the first quarter in four of their last five road games against teams that held a losing record.

Why the Arizona Cardinals will win

• The Rams have lost four of their last five October games as home favorites against NFC West opponents.
• The Cardinals have won six of their last eight games as road underdogs when playing with a rest advantage.
• The Cardinals have covered the spread in seven of their last eight games as road underdogs when playing with a rest advantage.
• The Rams have failed to cover the spread in each of their last four games without Tutu Atwell.
• The Rams have lost the first half in six of their last seven October games against NFC West opponents.
• The Rams have lost the first quarter in four of their last five Week 6 games as favorites.

Total Points Facts

• Each of the Rams’ last six Sunday day games have gone OVER the total points line.
• Each of the Cardinals’ last six games in October have gone OVER the total points line.
• Each of the last three Sunday games at SoFi Stadium have gone UNDER the total points line.

Los Angeles Rams Player Prop Facts

• Davante Adams has scored the first touchdown in three of his last four appearances at SoFi Stadium.
• Davante Adams has scored two touchdowns in three of his last four appearances at SoFi Stadium.
• Kyren Williams has scored the last touchdown in each of his four previous October appearances with the Rams as home favorites.
• Blake Corum has recorded 45+ rushing yards in seven of the Rams’ last eight day games.
• Blake Corum has recorded 61+ rushing and receiving yards in each of the Rams’ last seven games played on the West Coast.
• Matthew Stafford has recorded 317+ passing yards in each of the Rams’ last four games.
• Davante Adams has recorded 61+ receiving yards in nine of his last 10 appearances in day games with a total points line of at least 50.0.
• Matthew Stafford has recorded 24+ completions in each of the Rams’ last eight games as favorites with a total points line of at least 50.0.
• Kyren Williams has scored at least one touchdown in each of the Rams’ last six games against NFC opponents.
• Heading into Week 6, Matthew Stafford ranks 1st in the NFL in passing yards (1572) this season.

Arizona Cardinals Player Prop Facts

• Trey McBride has recorded 65+ receiving yards in each of the Cardinals’ last eight Sunday games as road underdogs.
• Jacoby Brissett has recorded 243+ passing yards in each of the Cardinals’ last seven games as heavy underdogs (>+7.0 points).
• Jacoby Brissett has recorded 25+ completions in four of the Cardinals’ last five games as heavy underdogs (>+7.0 points).
• Jacoby Brissett has recorded 10+ rushing yards in each of his last eight October appearances with his team as an underdog.
• James Conner has scored at least one touchdown in each of his last seven appearances against teams that held a losing record.
• James Conner has recorded 77+ rushing and receiving yards in each of his last 13 appearances following a home loss.
• Heading into Week 6, Trey McBride ranks 1st in the NFL in receptions (42) this season.

Matchup/League Facts

• Rams – seven different players have recorded 50+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
• Rams – five different players have recorded 60+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
• Heading into Week 6, the Cardinals rank 32nd in the NFL in points allowed per game (32.4) this season.
• Heading into Week 6, the Cardinals rank 32nd in the NFL in Q3 opponent points per game (9.0) this season.

Arizona Cardinals vs. Los Angeles Rams Prediction

I’m on the Rams in this one. I get the case to be made for an underdog in certain spots, but the Rams might be the most talented 2-3 team you’ll see and the Cardinals are just flat out a mess defensively. I don’t think the Cardinals have it in them to hang around in a spot like this so give me the Rams at home here laying the massive number.