Lions vs Browns Prediction 9/28/25 NFL Picks Today

In this article we will formulate a Lions vs Browns prediction for this NFL game on Sunday, September 28th at Ford Field in Detroit, Michigan. Let’s take a look at the prediction for this week 4 matchup.

Detroit Lions Betting Preview

The Detroit Lions are 2-1 this season after they defeated Baltimore by a score of 38-30 in their last game. Detroit was tied at 14 at the half and tied at 21 headed into the fourth, but they scored 17 points in the final quarter for the victory. The Lions out gained Baltimore by a total of 426-318, went 7-14 on third downs, and won the turnover battle by a total of 1-0 in the game. Jared Goff went 20-28 for 202 yards and one touchdown, while David Montgomery rushed 12 times for 151 yards and two scores. Amon-Ra St. Brown led the receivers with seven catches for 77 yards and one touchdown in the win. The Detroit defense recorded seven sacks and six tackles for loss in the victory. 

Detroit started the season with a 27-13 loss to Green Bay, but they did win their second game by a score of 52-21 against Chicago. The Lions are averaging 34.3 points per game with 245.3 passing yards and 149.0 rushing yards per game, while they are allowing 26.0 points against per game this season. Jared Goff has completed 77.9% of his passes for 761 yards, seven touchdowns, and one interception, while Amon-Ra St. Brown has caught 20 passes for 237 yards and four scores. David Montgomery has led the rushing attack with 233 yards and three touchdowns on 34 carries this season. 

Cleveland Browns Betting Preview

The Cleveland Browns are 1-2 this year after they defeated Green Bay by a score of 13-10 last time out. Cleveland trailed 10-0 in the fourth quarter, but they blocked a potential winning field goal and managed to kick their own field goal at the end of regulation for the win. The Browns were out gained by a total of 230-221, went 4-13 on third downs, and tied the turnover battle at one in the game. Joe Flacco went 21-36 for 142 yards and one interception, while Quinshon Judkins carried the ball 18 times for 94 yards and one score. David Njoku led the Cleveland receivers with five catches for 40 yards in the game. The Cleveland defense recorded five sacks and six tackles for loss in the victory. 

Cleveland started the season with a 17-16 loss to Cincinnati and a 41-17 loss to Baltimore in their first two games. The Browns are averaging 15.3 points per game with 203.7 passing yards and 86.7 rushing yards per game, while they are allowing 22.7 points against per game this season. Joe Flacco has completed 61.1% of his passes for 631 yards, two touchdowns, and four interceptions, while Harold Fannin Jr has caught 15 passes for 136 yards. Quinshon Judkins has led the rushing attack with 155 yards and one touchdown on 28 carries this year. 

Why the Lions will beat the Browns

• The Browns have lost each of their last 16 interstate games when playing with a rest advantage.
• The Lions have won each of their last eight games following a road win.
• The Browns have failed to cover the spread in each of their last seven road games when playing with a rest advantage.
• The Lions have covered the spread in each of their last six Sunday games against teams that held a losing record.
• The Lions have won the first quarter in eight of their last nine home games.
• The Lions have scored the first touchdown in eight of their last nine home games.
• The Lions have won the first half in each of their last 13 Sunday games against teams that held a losing record.

Why the Browns will beat the Lions

• The Lions have lost four of their last five games as favorites against AFC North opponents.
• The Browns have won each of their last two September games as underdogs against NFC opponents.
• The Browns have covered the spread in five of their last six games against NFC North opponents.
• The Lions have failed to cover the spread in four of their last five games as favorites against AFC North opponents.
• The Lions have lost the first quarter in three of their last four games as favorites against AFC opponents.
• The Browns have won the first half in five of their last six games against the Lions.

Total Points Facts

• Each of the Browns’ last nine road games following a win have gone OVER the total points line.
• Each of the Lions’ last five Week 4 home games have gone OVER the total points line.
• Four of the last five Sunday games at Ford Field have gone OVER the total points line.

Detroit Lions Player Prop Facts

• Jahmyr Gibbs has scored the first touchdown in four of the Lions’ last five games.
• Jahmyr Gibbs has scored two or more touchdowns in four of the Lions’ last five games following a win.
• Jared Goff has recorded 243+ passing yards in 11 of his last 12 September appearances with his team as a home favorite.
• Jahmyr Gibbs has recorded 69+ rushing yards in each of the Lions’ last eight games following a road win.
• Jahmyr Gibbs has scored at least one touchdown in each of the Lions’ last seven games as favorites.
• Kalif Raymond has recorded 12+ receiving yards in each of his last nine home appearances against AFC opponents.
• Jahmyr Gibbs has recorded 99+ rushing and receiving yards in each of the Lions’ last 10 games against AFC opponents.
• Jared Goff has recorded 24+ completions in five of the Lions’ last six home games against AFC opponents.
• Heading into Week 4, Amon-Ra St. Brown ranks T1st in the NFL in touchdowns (4) this season.

Cleveland Browns Player Prop Facts

• Jerry Jeudy has recorded 51+ receiving yards in each of his seven previous September road appearances.
• Joe Flacco has recorded 222+ passing yards in 20 of his last 24 appearances with his team as an underdog following a win.
• Jerome Ford has recorded 32+ rushing and receiving yards in 11 of his last 12 appearances with the Browns as road underdogs.
• Deshaun Watson has scored a touchdown in three of his five previous Week 4 appearances.
• Jerome Ford has recorded 14+ rushing yards in each of his last seven appearances with the Browns as road underdogs.
• Deshaun Watson has recorded 21+ completions in each of his last six September appearances.
• Heading into Week 4, Dylan Sampson ranks T1st amongst qualified players for catch rate (100.0%) this season.

Matchup/League Facts

• Lions – three different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 4.
• Lions – two different players have recorded 70+ rushing yards in a game this season – equal-most in the NFL, heading into Week 4.
• Heading into Week 4, the Browns rank 1st in the NFL in yards allowed per game (204.3) this season.
• Heading into Week 4, the Browns rank 1st in the NFL in rushing yards allowed per game (57.3) this season.

Lions vs Browns Prediction 

Detroit rolls into this matchup after dismantling Baltimore last week and they have plenty of momentum coming into this game. The Lions have looked very strong offensively in their last two games, but this Cleveland defense is still very good. The Browns are not a good offensive team, but they have not allowed many yards to the Packers or Ravens in their last two games. On the other side, the Detroit defense has been great in their last two games and their d-line really showed up last week. Take the under here. 

David Racey went 8-0 (100%) in the NFL last week and he is #1 on the NFL leaderboard. Click here for his premium plays for this week!