The Buffalo Bills and the Los Angeles Chargers meet in week 16 NFL action from SoFi Stadium on Saturday night. Can the Bills continue their playoff push on the road? Or will the Chargers look to play spoiler with their new head coach? Let’s take a look with our Bills vs. Chargers Prediction.

Buffalo Bills Team Preview

The Buffalo Bills come into this game looking to build on back-to-back wins after a 31-10 win over Dallas last time out. Josh Allen has thrown for 3,541 yards, 26 touchdowns and 14 interceptions on 66.3% passing while James Cook leads the Bills with 968 rushing yards. Stefon Diggs has a team-high 91 receptions for 1,041 yards and 8 touchdowns while Gabe Davis has 39 grabs for 595 yards and 6 scores. Three more Bills have at least 400 receiving yards as well on the year. On defense, Terrel Bernard has a team-high 117 total tackles with 3.5 sacks and 3 interceptions while Leonard Floyd has a team-high 10.5 sacks this season. A.J. Epenesa and Ed Oliver each have 6.5 sacks as well on the year.

Buffalo Bills Team Facts

• The Bills have won each of their last eight games in December.
• The Bills have covered the spread in seven of their last eight games as favorites against AFC West opponents.
• The Bills have scored the first touchdown in seven of their last eight road games against AFC West opponents.
• The Bills have lost the first quarter in four of their last five games against teams that held a losing record.
• The Bills have won the first half in eight of their last nine December games against AFC opponents.

Los Angeles Chargers Team Preview

The Los Angeles Chargers come into this game looking for a bounce back, after a 63-21 dismantling loss at the hands of the Las Vegas Raiders last time out. Justin Herbert has thrown for 3,134 yards, 20 touchdowns and 7 interceptions on 65.1% passing while Austin Ekeler has a team-high 506 rushing yards with 5 touchdowns and Joshua Kelley has 404 rushing yards as well on the year. Keenan Allen leads the Chargers’ receiving group with 108 grabs for 1,243 yards and 7 touchdowns this season. On defense, Kenneth Murray Jr. has a team-high 103 total tackles while Khalil Mack has a team-high 15 sacks and Joey Bosa has 6.5 sacks.

Los Angeles Chargers Team Facts

• The Chargers have lost each of their last nine games as heavy underdogs (>+7.0 points).
• The Chargers have failed to cover the spread in seven of their last eight December games as home underdogs.
• The Chargers have won the first half in each of their last three games as heavy underdogs (>+7.0 points).
• The Chargers have scored the first touchdown in six of their last seven games following a road loss.
• The Chargers have won the first quarter in each of their last three games as heavy underdogs (>+7.0 points).

Matchup/League Facts

• The Chargers rank 2nd in the NFL in average punt return this season (16.4 yards).
• The Chargers rank 2nd in the NFL in punt return yards per game this season (25.7).
• The Bills rank 32nd in the NFL in total punt yards this season (1795).
• The Bills rank 1st in the NFL in 3rd down percentage this season (49.2%).

Bills vs. Chargers Prediction

I’m on the Bills here. I’ve just mentally checked out of my relationship with the Los Angeles Chargers as I’m just so done with this team and they’re simply watching their season go up in smoke with these injuries and coach firings and I think the Chargers have simply hit the point of no return. Give me the Bills, who are in the midst of the playoff hunt and are once again becoming a serious threat in the AFC East.