Panthers vs Saints Prediction 11/9/25 NFL Picks Today

David Racey

New Orleans Saints (1-8) vs. Carolina Panthers (5-4)
November 9, 2025 1:00 pm EDT
The Line: Carolina Panthers -5.5; Over/Under: 39.5
(Get latest betting odds)

In this article we will formulate a Panthers vs Saints prediction for this NFL game on Sunday, November 9th at Bank of America Stadium in Charlotte, North Carolina. Let’s take a look at the prediction for this week 10 matchup.

Carolina Panthers Betting Preview

The Carolina Panthers are 5-4 this year after they defeated Green Bay by a score of 16-13 in their last game. Carolina led 7-6 at halftime, but they blew a 13-6 lead late in the fourth, before winning on a last second field goal. The Panthers were out gained by a total of 369-265, went 4-10 on third downs, and won the turnover battle by a total of 2-1 in the game. Bryce Young went 11-20 for 102 yards and one interception, while Rico Dowdle rushed 25 times for 130 yards and two scores. Tetairoa McMillan led the receivers with four receptions for 46 yards in the win. The Carolina defense recorded one sack and four tackles for loss in the game.

Prior to that game, Carolina lost to the Bills by a score of 40-9, but did beat the Jets by a score of 13-6 before that. The Panthers have won four of their last five games and they are currently second in the NFC South standings. Carolina has scored 18.9 points per game with 170.9 passing yards and 139.8 rushing yards per game, while they have allowed 22.8 points against per game this season. Bryce Young has thrown for 1,390 yards, 11 touchdowns, and six interceptions, while Rico Dowdle has rushed for 735 yards and four scores on 131 carries this year.

New Orleans Saints Betting Preview

The New Orleans Saints are 1-8 this season after they lost to the Rams by a score of 34-10 in their last game. New Orleans trailed 20-10 at halftime and was outscored 14-0 in the second half for the blowout loss. The Saints were out gained by a total of 438-224, went 2-9 on third downs, and lost the turnover battle by a margin of 2-0 in the game. Tyler Shough went 15-24 for 176 yards, one touchdown, and one interception, while Taysom Hill rushed four times for 30 yards. Rashid Shaheed led the receivers with five catches for 68 yards in the loss. The NO defense recorded two sacks and four tackles for loss in the game.

Prior to that game, New Orleans lost to the Buccaneers by a score of 23-3 and the Bears by a score of 26-14. The Saints have lost four games in a row and they are currently last in the NFC South standings. New Orleans has scored 15.3 points per game with 197.6 passing yards and 89.6 rushing yards per game, while they have allowed 27.0 points against per game this season. Tyler Shough has thrown for 304 yards, one touchdown, and two interceptions, while Chris Olave has 55 receptions for 560 yards and three scores this season.

Why the Carolina Panthers will win

The Saints have lost each of their last eight road games in November.
The favorites have won each of the Saints’ last 15 games.
The Saints have failed to cover the spread in each of their last seven games before a Division game.
The favorites have covered the spread in eight of the Saints’ last nine games.
The favorites have won the first half in each of the Saints’ last nine games.
The Saints have lost the first quarter in eight of their last nine games.
The Panthers have scored the first touchdown in each of their last 10 Week 10 games.

Total Points Facts

Ten of the Panthers’ last 11 games at Bank of America Stadium have gone OVER the total points line.
Each of the Saints’ last five games have gone UNDER the total points line.
Four of the last five games between teams from the same division have gone OVER the total points line.

Carolina Panthers Player Prop Facts

Chuba Hubbard has recorded 28+ rushing yards in each of his last 25 appearances in Sunday games played on the East Coast.
Chuba Hubbard has scored at least one touchdown in each of the Panthers’ last four games at Bank of America Stadium against teams on a losing streak.
Andy Dalton has recorded 214+ passing yards in each of his last four November appearances with his team as a favorite.
Tommy Tremble has recorded 11+ receiving yards in each of his last eight home appearances against NFC opponents.
Chuba Hubbard has recorded 34+ rushing and receiving yards in each of his last 30 appearances on the East Coast.
Heading into Week 10, Bryce Young has recorded the equal-most pass attempts in a single game this season (55 vs Cardinals, Week 2).

New Orleans Saints Player Prop Facts

Alvin Kamara has recorded 39+ rushing yards in each of his last 10 appearances in Sunday games played on the East Coast.
Taysom Hill has scored at least one touchdown in each of his last three road appearances against NFC South opponents.
Spencer Rattler has recorded 218+ passing yards in each of his last three road appearances against NFC opponents.
Brandin Cooks has recorded 10+ receiving yards in each of his 42 previous appearances on the East Coast.
Brandin Cooks has recorded 16+ rushing and receiving yards in each of his 31 previous appearances against NFC South opponents.
Heading into Week 10, Spencer Rattler has thrown the equal-most interceptions in a single game this season (3 vs Bears, Week 7).

Matchup/League Facts

Heading into Week 10, the Panthers rank 1st in the NFL in 4th down attempts (21) this season.
Heading into Week 10, the Panthers rank 32nd in the NFL in Q2 opponent points per game (11.2) this season.
Heading into Week 10, the Saints rank 32nd in the NFL in time of possession per game (26:38) this season.
Heading into Week 10, the Saints rank 32nd in the NFL in 4th down percentage (29.4%) this season.