Ravens vs Bills Prediction 9/7/25 NFL Picks Today

In this article, we will formulate a Ravens vs Bills Prediction for this NFL Week 1 game on Sunday, September 7^th at the Highmark Stadium. Let’s take a look at the prediction for this NFL matchup.

Buffalo Bills Preview

Buffalo finished the preseason with a 1-2 record. They lost at home by the Giants 25-34, and in Chicago by 0-38, while winning their final game in Tampa Bay by 23-19.

Offensively, Buffalo finished the preseason averaging 16.0 points per game, while allowing 30.3 points per game defensively. The Bills averaged 80.0 rushing yards and 234.7 passing yards per game. They allowed 98.3 rushing yards per game and 290.0 passing yards per game.

Shane Buechele led the Bills in the preseason with 36/46 completed passes and 380 total passing yards. He also had 1 touchdown and 0 interceptions. Mitchell Trubisky had 16/26 passes for 193 passing yards and 1 touchdown, while Mike White added 12/24 passes for 166 passing yards and 2 touchdowns. Frank Gore Jr. led the team in rushing yards, with 104 and 1 touchdown, while Tyrell Shavers had a team-high 9 caught passes for 123 receiving yards, and had 1 touchdown.

Defensively, Joe Andreessen had a team-high 16 total tackles, while Kameron Cline had a team-high 2.0 total sacks, and Trevon Diggs had a team-high 1 interception.

Baltimore Ravens Preview

Baltimore finished the preseason with a perfect 3-0 record. They won Indianapolis at home by 24-16, Dallas on the road by 31-13 and Washington on the road by 30-3.

Offensively, Baltimore finished the preseason averaging 15.0 points per game, while allowing 17.0 points per game defensively. The Ravens averaged 104.3 rushing yards and 176.7 passing yards per game. They allowed 121.7 rushing yards per game and 151.7 passing yards per game.

Cooper Rush led the Ravens in the preseason with 27/39 completed passes and 273 passing yards. He also had 1 touchdown and 3 interceptions. Devin Leary had 25/45 passes for 167 passing yards and 1 interception. D’Ernest Johnson led the team in rushing yards, with 163 and 2 touchdowns, while LaJohntay Wester had a team-high 9 caught passes for 69 receiving yards.

Defensively, Jay Higgins IV had a team-high 15 total tackles, 6 of them solo, while Trenton Simpson had a team-high 1.5 total sacks.

Why the Buffalo Bills will win

• The Bills have won each of their last 10 home games.
  The Ravens have lost four of their five previous games at Highmark Stadium.
  The home team has covered the spread in seven of the last eight games between the Ravens and Bills.
  The Ravens have failed to cover the spread in three of their last four Sunday games.
  The Bills have won the first quarter in four of their last five season openers.
  The Bills have scored the first touchdown in four of their last five Week 1 games.
  The Bills have won the first half in seven of their last eight home games in September.

Why the Baltimore Ravens will win

• The Ravens have won each of their last eight games before a Division game.
  The Bills have lost four of their last five September games against AFC North opponents.
  The Ravens have covered the spread in each of their last six road games before a Division game.
  The Bills have failed to cover the spread in each of their last five September games against AFC North opponents.
  The Ravens have won the first quarter in each of their last seven September games against AFC East opponents.
  The Ravens have scored the first touchdown in each of their last 11 Sunday games.
  The Ravens have won the first half in each of their last seven September games against AFC East opponents.

Total Points Facts

• Seven of the Bills’ last eight home games in September have gone OVER the total points line.
  Each of the Ravens’ last four road games in September have gone OVER the total points line.

Matchup/League Facts

• Bills – three different players recorded 80+ rushing yards in a game last season – equal-most in the NFL.
  Bills – 10 different players recorded 50+ receiving yards in a game last season – equal-most in the NFL.
  Ravens – two different players recorded 100+ rushing yards in a game last season – equal-most in the NFL.
  Ravens – 17 different players recorded 1.0 sacks or more in a game last season – equal-most in the NFL.

Ravens vs Bills Prediction

Both teams were tied 1-1 wins last season, with each one winning at home. Buffalo won by 27-25 and Baltimore 35-10. The Bills are 3-1 in their last 4 meetings against the Ravens, but the Ravens are 4-2-1 against the spread in their last 7 meetings. Under is 6-1-1 in their last 8 meetings.

In this Ravens vs Bills Prediction, the Bills are coming as -1-point home favorites. Buffalo was 12-8-0 ATS last season and cover the spread in all but three home games in 2024. The Ravens haven’t covered the spread on the road in Week 1 since 2019. The Ravens had a perfect preseason, and while they were underwhelming offensively, with just 15 points per game, they were dominating on the defensive end, allowing just 17 points per game. Buffalo was not that better offensively in the preseason, with just 16 points per game, and went scoreless in one of their three preseason games. Both of their meetings last season had an average of 48.5 total points, and under is 6-1-1 in their last 8 meetings. I expect another low-scoring affair today, so take the under 52.5 points in this one.