Seahawks vs Cardinals Prediction 9/20/26 NFL Picks Today

In this article, we will formulate a Seahawks vs Cardinals Prediction for this NFL Week 2 game on Sunday, September 20^th. Let’s take a look at the prediction for this NFL matchup.

Arizona Cardinals Preview

The Arizona Cardinals have a 1-0 record and are coming off a 26-14 road victory over the Los Angeles Chargers, where they outgained their opponents 393-268 yards and had 72 total plays. Arizona had 277 passing yards, 116 rushing yards, and 27/37 completed passes, while winning the turnover battle by 0-2. The Cardinals were 6/14 on third down conversions and 2/5 in the red zone.

Jacoby Brissett led Arizona with 27/37 passes, 277 passing yards, and one touchdown. Treshaun Allgeier had a team-high 61 rushing yards, while Trey McBride caught 9 passes for a team-high 95 receiving yards and 1 touchdown. Defensively, Jack Gibbens led the Cardinals with 7 total tackles, 5 of them solo, while Dante Stills had one sack.

Seattle Seahawks Preview

The Seattle Seahawks have a 1-0 record and are coming off a 13-10 home victory over the New England Patriots, where they outgained their opponents 285-277 yards and had 48 total plays. Seattle had 188 passing yards, 97 rushing yards, and 17/24 completed passes, while winning the turnover battle by 0-3. The Seahawks were 2/11 on third down conversions and 0/2 in the red zone.

Drew Lock led Seattle with 17/24 passes, 188 passing yards, and one touchdown. George Price had a team-high 52 rushing yards, while Jaxon Smith-Njigba caught 8 passes for a team-high 122 receiving yards and 1 touchdown. Defensively, Ernest Jones IV led the Seahawks with 13 total tackles, 8 of them solo, while Leonard Williams had one sack.

Seattle Seahawks @ Arizona Cardinals Betting Trends: Week 2

Why the Arizona Cardinals will win

• The Seahawks have lost each of their last seven road openers against NFC West opponents.
• The Cardinals have won eight of their last nine Week 2 home games.
• The Seahawks have failed to cover the spread in seven of their last eight games as favorites without Uchenna Nwosu.
• The Cardinals have covered the spread in seven of their last eight Week 2 games as underdogs.
• The home team has won the first quarter in each of the Cardinals’ last four Week 2 games.
• The Cardinals have scored the first touchdown in 11 of their last 13 Sunday home games.
• The home team has won the first half in each of the Cardinals’ last 10 Week 2 games.

Why the Seattle Seahawks will win

• The Cardinals have lost each of their last 13 games against opponents on a winning streak.
• The Seahawks have won each of their last 11 games.
• The Seahawks have covered the spread in each of their last six games when playing with a rest advantage.
• The Cardinals have failed to cover the spread in seven of their last eight home games.
• The Seahawks have won the first quarter in each of their last six games against teams that held a winning record.
• The Seahawks have scored the first touchdown in each of their last nine games as favorites against NFC West opponents.
• The Cardinals have lost the first half in each of their last 12 games as underdogs against NFC West opponents.

Total Points Facts

• Each of the Cardinals’ last eight September games as underdogs against NFC West opponents have gone UNDER the total points line.
• Each of the Seahawks’ last seven September games against NFC West opponents have gone UNDER the total points line.
• Nine of the last 10 Sunday games at State Farm Stadium have gone OVER the total points line.

Arizona Cardinals Player Prop Facts

• Jacoby Brissett has recorded 22+ completions in each of the Cardinals’ last four games against NFC West opponents.
• Jacoby Brissett has recorded 243+ passing yards in seven of the Cardinals’ last eight games against NFC opponents.
• Michael Wilson has recorded 52+ receiving yards in each of the Cardinals’ last six games.
• James Conner has recorded 86+ rushing yards in each of his last four home appearances against NFC West opponents.
• Kendrick Bourne has recorded 32+ rushing and receiving yards in each of his last six September appearances against NFC opponents.
• James Conner has scored at least one touchdown in each of his last four home appearances.
• Heading into Week 2, Chad Ryland ranks T1st in the NFL in made field goals (4) this season.

Seattle Seahawks Player Prop Facts

• Drew Lock has recorded 21+ completions in each of his last four road appearances as a starter.
• Drew Lock has recorded 210+ passing yards in three of his last four appearances as a starter.
• AJ Barner has recorded 24+ receiving yards in seven of the Seahawks’ last eight Sunday regular season road games.
• Zach Charbonnet has scored the first touchdown in each of his last three regular season appearances with the Seahawks as favorites.
• Zach Charbonnet has recorded 37+ rushing yards in eight of the Seahawks’ last nine road games against NFC opponents.
• Rashid Shaheed has recorded 42+ rushing and receiving yards in each of his last four September road appearances.
• Zach Charbonnet has scored a touchdown in each of the Seahawks’ last four regular season games as favorites against NFC West opponents.
• Heading into Week 2, Jaxon Smith-Njigba ranks T1st in the NFL in 20+ yard receiving touchdowns (1) this season.

Matchup/League Facts

• Cardinals – two different players have recorded 70+ receiving yards in a game this season – equal-most in the NFL, heading into Week 2.
• Heading into Week 2, the Cardinals rank T1st in the NFL in 4th down percentage against (0.0%) this season.
• Seahawks – three different players have recorded one interception or more in a game this season – most in the NFL, heading into Week 2.
• Heading into Week 2, the Seahawks rank T1st in the NFL in turnover differential (+3) this season.

Seahawks vs Cardinals Prediction

In this Seahawks vs Cardinals Prediction, the Seahawks are coming as -3.5 road favorites. Both teams are coming off wins in their opening games of the season and both looked excellent defensively, holding their opponents into just 14 and 10 points respectively. Seattle has been dominating Arizona in recent years, having won their last nine head-to-head meetings but they failed to cover the spread in their opening game at home, so I would rather go with the total in this one. Both teams went under in their first games, with 40 and 23 total points and two of their last three meetings in Arizona have also gone under. Take the under 40.5 in this one.